Gene Information gene info

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GENE：METTL17

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol METTL17
FullNmae methyltransferase like 17
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19280
EnsembleID ENSG00000165792
Uniprot Q9H7H0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
METTL17 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
METTL17 GO:0005515,GO:0005654,GO:0005759,GO:0006412,GO:0008757,GO:0032259,GO:0042274,GO:1904047

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR METTL17 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 METTL17 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 METTL17 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 METTL17 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP73 METTL17 19558638 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 METTL17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF METTL17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 METTL17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS METTL17 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000035CC3E METTL17 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD METTL17 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PPP1CB METTL17 25348397 N/A physical interaction ComPPI
ATXN1 METTL17 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
SF3B4 METTL17 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRT40 METTL17 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PNMA1 METTL17 24234451 25348397 25416956 26871637 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MDFI METTL17 14525934 16189514 24234451 25348397 26871637 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
FOSL2 METTL17 25348397 N/A physical interaction ComPPI
PPP1R12A METTL17 24234451 25348397 28330616 association pull down ComPPI,IntAct
KSR2 METTL17 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
TRIP6 METTL17 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAPK6 METTL17 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TRAF1 METTL17 24234451 25348397 25416956 26871637 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MDC1 METTL17 25348397 N/A physical interaction ComPPI
MID2 METTL17 25348397 N/A physical interaction ComPPI
TFIP11 METTL17 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CALCOCO2 METTL17 24234451 25348397 25416956 26871637 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HSPD1 METTL17 25348397 N/A physical interaction ComPPI
MYH9 METTL17 25348397 N/A physical interaction ComPPI
METTL17 CEP70 24234451 25348397 25416956 26871637 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
METTL17 CBY2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
METTL17 H1-1 25348397 N/A physical interaction ComPPI
MKI67 METTL17 24234451 26949251 association anti tag coimmunoprecipitation IntAct

Source Target Pmid Interactiontype Methods Database
URS00009C2556 METTL17 27087310 direct interaction,inhibition N/A NPInter

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