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GENE：MFF

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MFF
FullNmae mitochondrial fission factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24858
EnsembleID ENSG00000168958
Uniprot Q9GZY8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MFF apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MFF apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
MFF cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MFF GO:0000266,GO:0001836,GO:0005515,GO:0005739,GO:0005741,GO:0005777,GO:0005777,GO:0006626,GO:0006626,GO:0006626,GO:0008021,GO:0008053,GO:0010821,GO:0016559,GO:0031966,GO:0032991,GO:0042802,GO:0042803,GO:0043653,GO:0070584,GO:0090141,GO:0090141,GO:0090200,GO:0090314,GO:1900063

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR MFF 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 MFF 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF MFF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MFF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MFF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MFF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MFF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MFF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MFF 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 MFF 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00002FC5B0 MFF 20371350 23446348 23592263 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS0000330617 MFF 25416803 25431021 mrna cleavage,inhibition western blot TarBase
URS00001A7F58 MFF 20371350 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F MFF 20371350 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 MFF 20371350 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000195F5B MFF 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 MFF 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 MFF 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 MFF 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 MFF 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A MFF 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000058276F MFF 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A MFF 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B MFF 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC MFF 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB MFF 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 MFF 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 MFF 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE MFF 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 MFF 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC MFF 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C MFF 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 MFF 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000008DA94 MFF 25416803 28148392 mrna cleavage,inhibition experimental interaction detection,western blot TarBase

Source Target Pmid Interactiontype Methods Database
TOMM22 MFF 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
YWHAQ MFF 25348397 N/A physical interaction ComPPI
DNM1L MFF 24234451 25348397 26358295 physical association cross-linking study,physical interaction ComPPI,IntAct
DUSP22 MFF 25348397 N/A physical interaction ComPPI
TOMM20 MFF 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
DLST MFF 24234451 25348397 29128334 colocalization fluorescence microscopy ComPPI,IntAct
ILF3 MFF 25348397 N/A physical interaction ComPPI
MTNR1B MFF 24234451 25348397 26514267 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
PRKAA1 MFF 26816379 27898060 stimulant N/A OmniPath
MFF DNM1L 21149567 26358295 27898060 stimulant N/A OmniPath

Visualization










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