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GENE：MRM2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MRM2
FullNmae mitochondrial rRNA methyltransferase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16352
EnsembleID ENSG00000122687
Uniprot Q9UI43

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MRM2 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MRM2 GO:0000451,GO:0001510,GO:0005730,GO:0005739,GO:0005739,GO:0005759,GO:0006364,GO:0008650,GO:0008650,GO:0008650,GO:0008650,GO:0031167,GO:1902775

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 MRM2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 MRM2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TP53 MRM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003804D8 MRM2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004407DC MRM2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004900F1 MRM2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000353492 MRM2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 MRM2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 MRM2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002971AB MRM2 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
KBTBD7 MRM2 25348397 N/A physical interaction ComPPI
CAMK2D MRM2 25348397 N/A physical interaction ComPPI
BRCA1 MRM2 25348397 N/A physical interaction ComPPI
HSPD1 MRM2 25348397 N/A physical interaction ComPPI
SLC25A10 MRM2 25348397 N/A physical interaction ComPPI
MRPL12 MRM2 25348397 N/A physical interaction ComPPI
TSPAN5 MRM2 25348397 N/A physical interaction ComPPI

Visualization










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