GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
MRPL41
FullNmae
mitochondrial ribosomal protein L41
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:14492
EnsembleID
ENSG00000182154
Uniprot
Q8IXM3
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
MRPL41
cuproptosis
36010978
Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1.
Cuproptosis-related genes
Go Annotation:
GeneSymbol
Go id
MRPL41
GO:0003723,GO:0003735,GO:0003735,GO:0005515,GO:0005739,GO:0005743,GO:0005743,GO:0005762,GO:0005762,GO:0005762,GO:0006412,GO:0006412,GO:0006915,GO:0007049,GO:0032543,GO:1990904
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
ETS1
MRPL41
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
CTCF
MRPL41
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F4
MRPL41
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOS
MRPL41
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS00000C5969
MRPL41
19536157
25416803
mrna cleavage,inhibition
clip
TarBase
URS000029D793
MRPL41
19536157
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000EED18
MRPL41
19536157
25416803
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
EXOSC5
MRPL41
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
MRPL28
MRPL41
25348397
N/A
physical interaction
ComPPI
MRPL27
MRPL41
25348397
N/A
physical interaction
ComPPI
SMURF2
MRPL41
18157088
24234451
25348397
physical association
two hybrid
ComPPI,IntAct
NONO
MRPL41
25348397
N/A
physical interaction
ComPPI
NBR1
MRPL41
25348397
N/A
physical interaction
ComPPI
ABCD3
MRPL41
25348397
N/A
physical interaction
ComPPI
BTRC
MRPL41
25348397
N/A
physical interaction
ComPPI
KSR2
MRPL41
24234451
25348397
27086506
association
anti tag coimmunoprecipitation
ComPPI,IntAct
HNRNPL
MRPL41
25348397
N/A
physical interaction
ComPPI
CFTR
MRPL41
25348397
N/A
physical interaction
ComPPI
SOX2
MRPL41
25348397
N/A
physical interaction
ComPPI
TRIM63
MRPL41
18157088
24234451
25348397
physical association
two hybrid,pull down,physical interaction
ComPPI,IntAct
FUBP1
MRPL41
25348397
N/A
physical interaction
ComPPI
PLP2
MRPL41
25348397
N/A
physical interaction
ComPPI
CAND1
MRPL41
25348397
N/A
physical interaction
ComPPI
PDK1
MRPL41
24234451
25348397
29568061
association
proximity-dependent biotin identification
ComPPI,IntAct
AURKAIP1
MRPL41
24234451
25348397
29568061
association
proximity-dependent biotin identification
ComPPI,IntAct
TRIM55
MRPL41
25348397
N/A
physical interaction
ComPPI
GADD45GIP1
MRPL41
25348397
N/A
physical interaction
ComPPI
MRPL17
MRPL41
25348397
N/A
physical interaction
ComPPI
HNRNPA0
MRPL41
25348397
N/A
physical interaction
ComPPI
HSPD1
MRPL41
24234451
25348397
29568061
association
proximity-dependent biotin identification
ComPPI,IntAct
OGDH
MRPL41
25348397
N/A
physical interaction
ComPPI
ILF3
MRPL41
25348397
N/A
physical interaction
ComPPI
SLC25A10
MRPL41
25348397
N/A
physical interaction
ComPPI
MRPL44
MRPL41
25348397
N/A
physical interaction
ComPPI
MRPL20
MRPL41
25348397
N/A
physical interaction
ComPPI
MRPL4
MRPL41
25348397
N/A
physical interaction
ComPPI
MRPL12
MRPL41
25348397
N/A
physical interaction
ComPPI
MRPL19
MRPL41
25348397
N/A
physical interaction
ComPPI
SLX4
MRPL41
19596235
24234451
25348397
association
anti tag coimmunoprecipitation
ComPPI,IntAct
TP53
MRPL41
25348397
N/A
physical interaction
ComPPI
TSR1
MRPL41
25348397
N/A
physical interaction
ComPPI
MRPL10
MRPL41
25348397
N/A
physical interaction
ComPPI
TRMT61B
MRPL41
24234451
25348397
29568061
association
proximity-dependent biotin identification
ComPPI,IntAct
MRPL13
MRPL41
25348397
N/A
physical interaction
ComPPI
MRPL48
MRPL41
25348397
N/A
physical interaction
ComPPI
MRPL49
MRPL41
25348397
N/A
physical interaction
ComPPI
MRPL1
MRPL41
25348397
N/A
physical interaction
ComPPI
MRPL11
MRPL41
25348397
N/A
physical interaction
ComPPI
MRPL15
MRPL41
25348397
N/A
physical interaction
ComPPI
MRPL16
MRPL41
25348397
N/A
physical interaction
ComPPI
MRPL24
MRPL41
25348397
N/A
physical interaction
ComPPI
MRPL3
MRPL41
25348397
N/A
physical interaction
ComPPI
MRPL41
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL41
MRPL35
25348397
N/A
physical interaction
ComPPI
MRPL41
MRPS18A
25348397
N/A
physical interaction
ComPPI
MRPL41
MRPL34
25348397
N/A
physical interaction
ComPPI
Visualization