Gene Information gene info

GENE:MRPL53

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MRPL53
FullNmae mitochondrial ribosomal protein L53
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16684
EnsembleID ENSG00000204822
Uniprot Q96EL3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MRPL53 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MRPL53 GO:0005515,GO:0005739,GO:0005743,GO:0005743,GO:0005762,GO:0005762,GO:0005762,GO:0032543

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 MRPL53 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink

Source Target Pmid Interactiontype Methods Database
URS00001A7F58 MRPL53 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA MRPL53 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
SNRPC MRPL53 25348397 N/A physical interaction ComPPI
UBE2I MRPL53 25348397 N/A physical interaction ComPPI
MRPL53 USP44 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPL53 BABAM1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPL53 APP 25348397 N/A physical interaction ComPPI
MRPL53 MRRF 25348397 N/A physical interaction ComPPI
MRPL53 SPR 25348397 N/A physical interaction ComPPI
MRPL53 ZC3H11A 25348397 N/A physical interaction ComPPI
MRPL53 SUGP1 25348397 N/A physical interaction ComPPI
MRPL53 NABP2 25348397 N/A physical interaction ComPPI
MRPL53 RPS19 25348397 N/A physical interaction ComPPI
MRPL53 PFN1 25348397 N/A physical interaction ComPPI
MRPL53 RFX5 25348397 N/A physical interaction ComPPI
MRPL53 RPL38 25348397 N/A physical interaction ComPPI
MRPL53 PPIF 25348397 N/A physical interaction ComPPI
MRPL53 MPLKIP 25348397 N/A physical interaction ComPPI
MRPL53 RPS28 25348397 N/A physical interaction ComPPI
MRPL53 TAGLN 25348397 N/A physical interaction ComPPI
MRPL53 TPX2 25348397 N/A physical interaction ComPPI
MRPL53 UBE4B 25348397 N/A physical interaction ComPPI
MRPL53 PQBP1 25348397 N/A physical interaction ComPPI
MRPL53 PPIB 25348397 N/A physical interaction ComPPI
MRPL53 SCO2 25348397 N/A physical interaction ComPPI
MRPL53 UBE2L3 25348397 N/A physical interaction ComPPI
MRPL53 RBM27 25348397 N/A physical interaction ComPPI
MRPL53 VDAC3 25348397 N/A physical interaction ComPPI
MRPL53 SBDS 25348397 N/A physical interaction ComPPI
MRPL53 TBL2 25348397 N/A physical interaction ComPPI
MRPL53 TIAL1 25348397 N/A physical interaction ComPPI
MRPL53 THY1 25348397 N/A physical interaction ComPPI
MRPL53 MYC 21150319 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MRPL53 NPM1 25348397 N/A physical interaction ComPPI
MRPL53 KIF2A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MRPL53 TAX1BP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MRPL53 IKZF3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MRPL53 SSX2IP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MRPL53 MRPL4 25348397 N/A physical interaction ComPPI
MRPL53 MRPS30 25348397 N/A physical interaction ComPPI
MRPL53 MRPL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPL53 NDUFS3 25348397 N/A physical interaction ComPPI
MRPL53 MRPL12 25348397 N/A physical interaction ComPPI
MRPL53 SLC25A10 25348397 N/A physical interaction ComPPI
MRPL53 MRPL10 25348397 N/A physical interaction ComPPI
MRPL53 YBX1 22118625 24234451 25348397 association tandem affinity purification ComPPI,IntAct
MRPL53 HNRNPH1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MRPL53 ELOB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MRPL53 NFKBID 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MRPL53 THAP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MRPL53 PAX6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MRPL53 AURKAIP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPL53 HSPD1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPL53 PDK1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPL53 TRMT61B 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct

Visualization