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GENE：MRPS12

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MRPS12
FullNmae mitochondrial ribosomal protein S12
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10380
EnsembleID ENSG00000128626
Uniprot O15235

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MRPS12 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MRPS12 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MRPS12 GO:0003723,GO:0003735,GO:0003735,GO:0005515,GO:0005743,GO:0005743,GO:0005761,GO:0005763,GO:0005763,GO:0005763,GO:0005840,GO:0006412,GO:0032543,GO:0032543

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MRPS12 hsa:6183 path:hsa03010 Ribosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 MRPS12 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 MRPS12 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
MAD2L2 MRPS12 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
UNC119 MRPS12 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
EEA1 MRPS12 24234451 25348397 29568061 association pull down ComPPI,IntAct
MPHOSPH8 MRPS12 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBA1A MRPS12 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CDK7 MRPS12 24234451 25348397 29568061 association pull down ComPPI,IntAct
CRMP1 MRPS12 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RIF1 MRPS12 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
CKAP5 MRPS12 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TGOLN2 MRPS12 24234451 25348397 29568061 association pull down ComPPI,IntAct
MRPS12 ERG28 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MRPS12 RPS3 25348397 N/A physical interaction ComPPI
MRPS12 CNOT2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPS12 ZSCAN5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPS12 FBL 24234451 25348397 29568061 association pull down ComPPI,IntAct
SMARCB1 MRPS12 24234451 30108113 association pull down,proximity-dependent biotin identification IntAct

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