GENE：MRPS16
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | MRPS16 |
| FullNmae | mitochondrial ribosomal protein S16 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:14048 |
| EnsembleID | ENSG00000182180 |
| Uniprot | Q9Y3D3 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| MRPS16 | cuproptosis | 36010978 | Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. | Cuproptosis-related genes |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| MRPS16 | GO:0003735,GO:0003735,GO:0003735,GO:0005515,GO:0005739,GO:0005743,GO:0005743,GO:0005763,GO:0005763,GO:0005763,GO:0005829,GO:0006412,GO:0032543,GO:0032543 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| MRPS16 | hsa:51021 | path:hsa03010 | Ribosome - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000003ABC4 | MRPS16 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000033EBB8 | MRPS16 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000EC1BE | MRPS16 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000021D7C8 | MRPS16 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000F4AC3 | MRPS16 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00002E0524 | MRPS16 | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD002 | MRPS16 | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | MRPS16 | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000355E82 | MRPS16 | 21572407 23446348 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | MRPS16 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C1E1 | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002A8BC6 | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032AE90 | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E5ECC | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A760 | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000137EDE | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000019907A | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C5969 | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006372A | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004214BB | MRPS16 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C0099 | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000043C1C3 | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003FBC84 | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041FA2C | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CC4BD | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E728C | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B0B46 | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000076E54 | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E2232 | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031B6ED | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AD2AA | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EBD4B | MRPS16 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039A052 | MRPS16 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D814 | MRPS16 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075CC78 | MRPS16 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000045147B | MRPS16 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002AA55A | MRPS16 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001012BC | MRPS16 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000170CF4 | MRPS16 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A7F58 | MRPS16 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B989F | MRPS16 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FC5B0 | MRPS16 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C85B2 | MRPS16 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000021202F | MRPS16 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| RPS16 | MRPS16 | 25361965 | interaction type | N/A | PTMCode2 |
| MRPS16 | RPS16 | 25361965 | interaction type | N/A | PTMCode2 |
| MRPS16 | GFM1 | 25361965 | interaction type | N/A | PTMCode2 |
| GFM1 | MRPS16 | 25361965 | interaction type | N/A | PTMCode2 |
| RPS14 | MRPS16 | 25361965 | interaction type | N/A | PTMCode2 |
| MRPS16 | RPS14 | 25361965 | interaction type | N/A | PTMCode2 |
| MRPS11 | MRPS16 | 25361965 | interaction type | N/A | PTMCode2 |
| MRPS16 | MRPS11 | 25361965 | interaction type | N/A | PTMCode2 |
| MRPS7 | MRPS16 | 25361965 | interaction type | N/A | PTMCode2 |
| MRPS16 | MRPS7 | 25361965 | interaction type | N/A | PTMCode2 |
| TUFM | MRPS16 | 25361965 | interaction type | N/A | PTMCode2 |
| MRPS16 | TUFM | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| FAM50B | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| PSMD7 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| RRS1 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| SSBP1 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| PSMA5 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPU | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| TNIK | MRPS16 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| RPS6 | MRPS16 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| ZP3 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| VHL | MRPS16 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| PINX1 | MRPS16 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| CDC14B | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| SBF1 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| CAND1 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| PDK1 | MRPS16 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| HNRNPR | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| ELAVL1 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| PSMC1 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| PSMA7 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| AURKAIP1 | MRPS16 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| PRKAB1 | MRPS16 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| DUSP11 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| AGO1 | MRPS16 | 17932509 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| HSPD1 | MRPS16 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| MRPS34 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| MCC | MRPS16 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| SLC25A5 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| CEP76 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| COQ8A | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| PSMC2 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| ATXN10 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS26 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| MGST3 | MRPS16 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| MRPS9 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| SLX4 | MRPS16 | 19596235 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| PHLDA3 | MRPS16 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| MRPS25 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPDL | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS27 | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| TRMT61B | MRPS16 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| MRPL58 | MRPS16 | 20186120 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MCAT | MRPS16 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS16 | MRPS2 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS16 | MPV17 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS16 | TRMT10B | 25348397 | N/A | physical interaction | ComPPI |
| MRPS16 | COQ4 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS16 | FAM136A | 25348397 | N/A | physical interaction | ComPPI |
| MRPS16 | COQ5 | 24234451 25348397 27499296 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| SGG | MRPS16 | 25348397 | N/A | pull down | ComPPI |
| DALLY | MRPS16 | 24234451 25294943 25348397 | association | pull down | ComPPI,IntAct |
| MKI67 | MRPS16 | 24234451 26949251 | association | anti tag coimmunoprecipitation | IntAct |