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GENE：MRPS18A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MRPS18A
FullNmae mitochondrial ribosomal protein S18A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14515
EnsembleID ENSG00000096080
Uniprot Q9NVS2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MRPS18A immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MRPS18A cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MRPS18A GO:0003735,GO:0003735,GO:0003735,GO:0005739,GO:0005743,GO:0005743,GO:0005762,GO:0005762,GO:0005763,GO:0005763,GO:0006412,GO:0006412,GO:0032543,GO:0032543,GO:0070181

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MRPS18A hsa:55168 path:hsa03010 Ribosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP MRPS18A 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 MRPS18A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 MRPS18A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 MRPS18A 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MRPS18A 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MRPS18A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MRPS18A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MRPS18A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MRPS18A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MRPS18A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MRPS18A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MRPS18A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MRPS18A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MRPS18A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MRPS18A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MRPS18A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 MRPS18A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 MRPS18A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000BE495 MRPS18A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005485E8 MRPS18A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000047A67D MRPS18A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075C3F6 MRPS18A 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NOL12 MRPS18A 25348397 N/A physical interaction ComPPI
MRPL28 MRPS18A 25348397 N/A physical interaction ComPPI
JUN MRPS18A 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
BTRC MRPS18A 25348397 N/A physical interaction ComPPI
PDK1 MRPS18A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRIM25 MRPS18A 25348397 N/A physical interaction ComPPI
RPL6 MRPS18A 25348397 N/A physical interaction ComPPI
RPL13 MRPS18A 25348397 N/A physical interaction ComPPI
FOXL2 MRPS18A 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
AURKAIP1 MRPS18A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
FBXW11 MRPS18A 25348397 N/A physical interaction ComPPI
HNRNPA1 MRPS18A 25348397 N/A physical interaction ComPPI
CYLD MRPS18A 25348397 N/A physical interaction ComPPI
MRPL42 MRPS18A 25348397 N/A physical interaction ComPPI
MRPL4 MRPS18A 25348397 N/A physical interaction ComPPI
MGST3 MRPS18A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NIPSNAP1 MRPS18A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPL9 MRPS18A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
APP MRPS18A 25348397 N/A physical interaction ComPPI
MRPL10 MRPS18A 25348397 N/A physical interaction ComPPI
MRPL39 MRPS18A 25348397 N/A physical interaction ComPPI
TRMT61B MRPS18A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPL58 MRPS18A 20186120 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPL1 MRPS18A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPL41 MRPS18A 25348397 N/A physical interaction ComPPI
MRPL47 MRPS18A 25348397 N/A physical interaction ComPPI
MRPL50 MRPS18A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPS18A ZNF22 25348397 N/A physical interaction ComPPI
MRPS18A RBMS3 25348397 N/A physical interaction ComPPI
MRPS18A MRPS30 25348397 N/A physical interaction ComPPI
MRPS18A ZNF317 25348397 N/A physical interaction ComPPI
MRPS18A MRPL35 25348397 N/A physical interaction ComPPI

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