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GENE：MRPS21

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MRPS21
FullNmae mitochondrial ribosomal protein S21
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14046
EnsembleID ENSG00000266472
Uniprot P82921

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MRPS21 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MRPS21 GO:0003723,GO:0003735,GO:0003735,GO:0005743,GO:0005743,GO:0005763,GO:0005763,GO:0006412,GO:0032543,GO:0032543

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MRPS21 hsa:54460 path:hsa03010 Ribosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MRPS21 RNF2 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 MRPS21 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 MRPS21 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 MRPS21 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink

Source Target Pmid Interactiontype Methods Database
URS0000077AED MRPS21 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000029979D MRPS21 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000157F5 MRPS21 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000031E12 MRPS21 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075A9CF MRPS21 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001E3523 MRPS21 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003BD367 MRPS21 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 MRPS21 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000021202F MRPS21 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001A7F58 MRPS21 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000B989F MRPS21 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 MRPS21 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C85B2 MRPS21 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000939AF MRPS21 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075D814 MRPS21 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 MRPS21 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00005CCD18 MRPS21 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B MRPS21 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000035CC3E MRPS21 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC MRPS21 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA MRPS21 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000016C318 MRPS21 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002367FA MRPS21 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000027352D MRPS21 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003D4175 MRPS21 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 MRPS21 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00006097A6 MRPS21 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 MRPS21 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004283FE MRPS21 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000D2680 MRPS21 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NDUFAF3 MRPS21 25348397 N/A physical interaction ComPPI
CUL3 MRPS21 25348397 N/A physical interaction ComPPI
RPLP2 MRPS21 25348397 N/A physical interaction ComPPI
RNF2 MRPS21 25348397 N/A physical interaction ComPPI
TUBGCP3 MRPS21 25348397 N/A physical interaction ComPPI
CDC14B MRPS21 25348397 N/A physical interaction ComPPI
CAND1 MRPS21 25348397 N/A physical interaction ComPPI
HNRNPR MRPS21 25348397 N/A physical interaction ComPPI
ESR2 MRPS21 21182203 24234451 25348397 association affinity chromatography technology ComPPI,IntAct
RPL6 MRPS21 25348397 N/A physical interaction ComPPI
RBM42 MRPS21 25348397 N/A physical interaction ComPPI
AURKAIP1 MRPS21 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TRA2A MRPS21 25348397 N/A physical interaction ComPPI
DUSP11 MRPS21 25348397 N/A physical interaction ComPPI
LAMTOR2 MRPS21 25348397 N/A physical interaction ComPPI
LDHD MRPS21 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SHMT2 MRPS21 25348397 N/A physical interaction ComPPI
MYL12B MRPS21 25348397 N/A physical interaction ComPPI
HSPD1 MRPS21 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPS34 MRPS21 25348397 N/A physical interaction ComPPI
MGST3 MRPS21 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPS9 MRPS21 25348397 N/A physical interaction ComPPI
MRPS31 MRPS21 25348397 N/A physical interaction ComPPI
SLX4 MRPS21 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MYL12A MRPS21 25348397 N/A physical interaction ComPPI
NXF1 MRPS21 25348397 N/A physical interaction ComPPI
MOV10 MRPS21 25348397 N/A physical interaction ComPPI
RPS21 MRPS21 25348397 N/A physical interaction ComPPI
USP42 MRPS21 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP44 MRPS21 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFS2 MRPS21 25348397 N/A physical interaction ComPPI
MRPS21 MRPL58 20186120 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPS21 ZC3H3 25348397 N/A physical interaction ComPPI
MRPS21 TRMT10B 25348397 N/A physical interaction ComPPI
MRPS21 MRPS15 25348397 N/A physical interaction ComPPI
MRPS21 MRPS11 25348397 N/A physical interaction ComPPI
MRPS21 MRPS27 25348397 N/A physical interaction ComPPI
MRPS21 COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct

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