GENE：MRPS23
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | MRPS23 |
| FullNmae | mitochondrial ribosomal protein S23 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:14509 |
| EnsembleID | ENSG00000181610 |
| Uniprot | Q9Y3D9 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| MRPS23 | cuproptosis | 36010978 | Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. | Cuproptosis-related genes |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| MRPS23 | GO:0003723,GO:0003735,GO:0005515,GO:0005739,GO:0005739,GO:0005743,GO:0005743,GO:0005763,GO:0031965,GO:0032543 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ESR1 | MRPS23 | 18414489 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,chromatin immunoprecipitation assay | TFlink |
| ETS1 | MRPS23 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | MRPS23 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | MRPS23 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA3 | MRPS23 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | MRPS23 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| MYC | MRPS23 | 18414489 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| YBX1 | MRPS23 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | MRPS23 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | MRPS23 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | MRPS23 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | MRPS23 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | MRPS23 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | MRPS23 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | MRPS23 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | MRPS23 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | MRPS23 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00001A7F58 | MRPS23 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000F6E49 | MRPS23 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000D5FFC | MRPS23 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000048D44E | MRPS23 | 20371350 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CF056 | MRPS23 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000254A6 | MRPS23 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001067D1 | MRPS23 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000243FF1 | MRPS23 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003380CC | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EEF5F | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000008A99 | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000367985 | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C85B2 | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AB32B | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003B6B84 | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A760 | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000007F792 | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000086A4D | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A281 | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD002 | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000005CE28 | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000024CEE0 | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001496AE | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00005CC20C | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | MRPS23 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000475586 | MRPS23 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000075BDA4 | MRPS23 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| VCP | MRPS23 | 25348397 | N/A | physical interaction | ComPPI |
| DCUN1D1 | MRPS23 | 25348397 | N/A | physical interaction | ComPPI |
| H3C1 | MRPS23 | 24234451 25348397 29568061 | association | pull down | ComPPI,IntAct |
| AURKAIP1 | MRPS23 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| TRMT61B | MRPS23 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| MRPS23 | SRRM2 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | CUL3 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | CUL1 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | COPS5 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | CAND1 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | QARS1 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | SMURF1 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | FN1 | 19738201 24234451 25348397 | association | cross-linking study,physical interaction | ComPPI,IntAct |
| MRPS23 | VCAM1 | 19738201 22623428 24234451 25348397 | association | cross-linking study,physical interaction | ComPPI,IntAct |
| MRPS23 | C1QBP | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | ITGA4 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | PRKN | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | SMURF2 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | CEP250 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | CEP57 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | CEP76 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | TP53 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | TUBGCP3 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | TUBGCP4 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | USHBP1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| MRPS23 | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | FBXW11 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | TRA2A | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | RPL6 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | MRPS2 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | HNRNPA1 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | MRPS31 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | HSPB1 | 24234451 25277244 25348397 | physical association | reverse ras recruitment system,physical interaction | ComPPI,IntAct |
| MRPS23 | DAP3 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | MRPS22 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | PTCD3 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | ERBB3 | 24189400 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| MRPS23 | ZNF746 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | MRPS34 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | E4F1 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | MRPS11 | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | PPAN | 25348397 | N/A | physical interaction | ComPPI |
| MRPS23 | VHL | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| MRPS23 | ATG12 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| MRPS23 | AGO1 | 17932509 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| MRPS23 | SIRT4 | 24234451 25348397 25525879 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| MRPS23 | POLR1C | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| MRPS23 | AIFM1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| MRPS23 | HSPD1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| MRPS23 | FBL | 24234451 25348397 29568061 | association | pull down,proximity-dependent biotin identification | ComPPI,IntAct |
| MRPS23 | PDK1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| MRPS23 | SCO1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| MRPS23 | RPS6 | 24234451 25348397 29568061 | association | pull down | ComPPI,IntAct |