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GENE：MRPS25

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MRPS25
FullNmae mitochondrial ribosomal protein S25
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14511
EnsembleID ENSG00000131368
Uniprot P82663

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MRPS25 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MRPS25 GO:0003735,GO:0005739,GO:0005739,GO:0005743,GO:0005743,GO:0005763,GO:0032543

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 MRPS25 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 MRPS25 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MRPS25 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MRPS25 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MRPS25 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MRPS25 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MRPS25 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 MRPS25 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001C770D MRPS25 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016FD1A MRPS25 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000024DFCE MRPS25 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000061E50F MRPS25 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB16 MRPS25 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000605E00 MRPS25 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075C3F6 MRPS25 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 MRPS25 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 MRPS25 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000AF45F MRPS25 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC MRPS25 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C MRPS25 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002E177F MRPS25 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PCNA MRPS25 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPS5 MRPS25 25348397 N/A physical interaction ComPPI
KIFAP3 MRPS25 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
HNRNPU MRPS25 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
C1QBP MRPS25 25348397 N/A physical interaction ComPPI
RPS6 MRPS25 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
TUBGCP3 MRPS25 25348397 N/A physical interaction ComPPI
MME MRPS25 17342744 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CAND1 MRPS25 25348397 N/A physical interaction ComPPI
PDK1 MRPS25 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRIM25 MRPS25 25348397 N/A physical interaction ComPPI
AURKAIP1 MRPS25 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HNRNPAB MRPS25 25348397 N/A physical interaction ComPPI
TRA2A MRPS25 25348397 N/A physical interaction ComPPI
DDX56 MRPS25 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPD1 MRPS25 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPS34 MRPS25 25348397 N/A physical interaction ComPPI
CEP76 MRPS25 25348397 N/A physical interaction ComPPI
MRPS22 MRPS25 25348397 N/A physical interaction ComPPI
MRPS31 MRPS25 25348397 N/A physical interaction ComPPI
TP53 MRPS25 25348397 N/A physical interaction ComPPI
MRPS18B MRPS25 25348397 N/A physical interaction ComPPI
ERBB3 MRPS25 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MRPS25 MRPS7 25348397 N/A physical interaction ComPPI
MRPS25 MRPS16 25348397 N/A physical interaction ComPPI
MRPS25 ZC3H3 25348397 N/A physical interaction ComPPI
MRPS25 RPS8 25348397 N/A physical interaction ComPPI
MRPS25 MRPS11 25348397 N/A physical interaction ComPPI
TRMT61B MRPS25 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MKI67 MRPS25 24234451 26949251 association anti tag coimmunoprecipitation IntAct

Visualization










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