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GENE：MRPS2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MRPS2
FullNmae mitochondrial ribosomal protein S2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14495
EnsembleID ENSG00000122140
Uniprot Q9Y399

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MRPS2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MRPS2 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MRPS2 GO:0003735,GO:0003735,GO:0005739,GO:0005743,GO:0005743,GO:0005763,GO:0005763,GO:0005763,GO:0005763,GO:0032543,GO:0032543,GO:0061668

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MRPS2 hsa:51116 path:hsa03010 Ribosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 MRPS2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MRPS2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MRPS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MRPS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MRPS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MRPS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MRPS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MRPS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MRPS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 MRPS2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 MRPS2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EC1BE MRPS2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000B1C9 MRPS2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
MRPS2 MRPS7 25361965 interaction type N/A PTMCode2
MRPS7 MRPS2 25361965 interaction type N/A PTMCode2
MRPS2 RPS16 25361965 interaction type N/A PTMCode2
RPS16 MRPS2 25361965 interaction type N/A PTMCode2
MRPS2 MRPS11 25361965 interaction type N/A PTMCode2
MRPS11 MRPS2 25361965 interaction type N/A PTMCode2
MRPS2 TUFM 25361965 interaction type N/A PTMCode2
TUFM MRPS2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CUL5 MRPS2 25348397 N/A physical interaction ComPPI
TPD52L2 MRPS2 25348397 N/A physical interaction ComPPI
FASTKD3 MRPS2 20869947 24234451 25348397 association tandem affinity purification ComPPI,IntAct
ZBTB48 MRPS2 25348397 N/A physical interaction ComPPI
ZNF707 MRPS2 25348397 N/A physical interaction ComPPI
JUN MRPS2 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
DAP3 MRPS2 25348397 N/A physical interaction ComPPI
NTRK1 MRPS2 25348397 N/A physical interaction ComPPI
SSBP1 MRPS2 25348397 N/A physical interaction ComPPI
E4F1 MRPS2 25348397 N/A physical interaction ComPPI
HNRNPU MRPS2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
C1QBP MRPS2 25348397 N/A physical interaction ComPPI
RPS6 MRPS2 24234451 25348397 29568061 association pull down ComPPI,IntAct
TUBGCP3 MRPS2 25348397 N/A physical interaction ComPPI
CDC14B MRPS2 25348397 N/A physical interaction ComPPI
CAND1 MRPS2 25348397 N/A physical interaction ComPPI
PDK1 MRPS2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ESR1 MRPS2 21182203 24234451 25348397 association pull down ComPPI,IntAct
ESR2 MRPS2 21182203 24234451 25348397 association affinity chromatography technology,physical interaction ComPPI,IntAct
RPL6 MRPS2 25348397 N/A physical interaction ComPPI
RBM42 MRPS2 25348397 N/A physical interaction ComPPI
AURKAIP1 MRPS2 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TRA2A MRPS2 25348397 N/A physical interaction ComPPI
DUSP11 MRPS2 25348397 N/A physical interaction ComPPI
CEP250 MRPS2 25348397 N/A physical interaction ComPPI
TPD52 MRPS2 25348397 N/A physical interaction ComPPI
KLC2 MRPS2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPD1 MRPS2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
OGDH MRPS2 25348397 N/A physical interaction ComPPI
MRPS34 MRPS2 25348397 N/A physical interaction ComPPI
ACTA2 MRPS2 25348397 N/A physical interaction ComPPI
HNRNPA1 MRPS2 25348397 N/A physical interaction ComPPI
PTCD3 MRPS2 25348397 N/A physical interaction ComPPI
MRPS22 MRPS2 25348397 N/A physical interaction ComPPI
MGST3 MRPS2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPS9 MRPS2 25348397 N/A physical interaction ComPPI
MRPS31 MRPS2 25348397 N/A physical interaction ComPPI
APP MRPS2 25348397 N/A physical interaction ComPPI
TP53 MRPS2 25348397 N/A physical interaction ComPPI
MRPS18B MRPS2 25348397 N/A physical interaction ComPPI
MRPS5 MRPS2 25348397 N/A physical interaction ComPPI
MRPS14 MRPS2 25348397 N/A physical interaction ComPPI
MRPS7 MRPS2 25348397 N/A physical interaction ComPPI
MRPS35 MRPS2 25348397 N/A physical interaction ComPPI
MRPS27 MRPS2 25348397 N/A physical interaction ComPPI
RNF157 MRPS2 25348397 N/A physical interaction ComPPI
TRMT61B MRPS2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPS23 MRPS2 25348397 N/A physical interaction ComPPI
ZNF746 MRPS2 25348397 N/A physical interaction ComPPI
MRPL58 MRPS2 20186120 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ERAL1 MRPS2 25348397 N/A physical interaction ComPPI
GRSF1 MRPS2 25348397 N/A physical interaction ComPPI
MRPS11 MRPS2 25348397 N/A physical interaction ComPPI
MRPS15 MRPS2 25348397 N/A physical interaction ComPPI
MRPS16 MRPS2 25348397 N/A physical interaction ComPPI
MRPS2 HSD17B8 25348397 N/A physical interaction ComPPI
MRPS2 MRPS28 25348397 N/A physical interaction ComPPI
MRPS2 MRPS33 25348397 N/A physical interaction ComPPI
MRPS2 MRPS18C 25348397 N/A physical interaction ComPPI
MRPS2 ZC3H3 25348397 N/A physical interaction ComPPI
MRPS2 TRMT10B 25348397 N/A physical interaction ComPPI
MRPS2 ZNF133 25348397 N/A physical interaction ComPPI

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