GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
MRPS30
FullNmae
mitochondrial ribosomal protein S30
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:8769
EnsembleID
ENSG00000112996
Uniprot
Q9NP92
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
MRPS30
cuproptosis
36010978
Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1.
Cuproptosis-related genes
Go Annotation:
GeneSymbol
Go id
MRPS30
GO:0003723,GO:0003735,GO:0005739,GO:0005743,GO:0005743,GO:0005762,GO:0005762,GO:0005762,GO:0006915,GO:0032543
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
MRPS30
EGR1
19032775
23180781
physical association
anti tag coimmunoprecipitation
InnateDB
Source
Target
Pmid
Interactiontype
Methods
Database
E2F4
MRPS30
17531812
trascriptional regulation,stimulation
chromatin immunoprecipitation array
TFlink
ETS1
MRPS30
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
SMARCA4
MRPS30
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CEBPA
MRPS30
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
MRPS30
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F1
MRPS30
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
EGR1
MRPS30
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOXA1
MRPS30
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOS
MRPS30
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HNF4A
MRPS30
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
PRDM14
MRPS30
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
TP53
MRPS30
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS000040EE1D
MRPS30
21572407
25416803
mrna cleavage,inhibition
clip,clip
TarBase
URS000017EE98
MRPS30
21572407
25416803
mrna cleavage,inhibition
clip,clip
TarBase
URS000038718E
MRPS30
21572407
25416803
mrna cleavage,inhibition
clip,clip
TarBase
URS000047A67D
MRPS30
23313552
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000250A40
MRPS30
23313552
25416803
mrna cleavage,inhibition
clip
TarBase
URS00005ACA7C
MRPS30
23313552
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000355E82
MRPS30
23313552
25416803
mrna cleavage,inhibition
clip
TarBase
URS000006372A
MRPS30
23313552
25416803
mrna cleavage,inhibition
clip
TarBase
URS000075AAA0
MRPS30
23313552
25416803
mrna cleavage,inhibition
clip
TarBase
URS000050CCE0
MRPS30
23313552
25416803
mrna cleavage,inhibition
clip
TarBase
URS00001EFBE3
MRPS30
23313552
25416803
mrna cleavage,inhibition
clip
TarBase
URS00001C0099
MRPS30
23313552
25416803
mrna cleavage,inhibition
clip
TarBase
URS00003FBC84
MRPS30
23313552
25416803
mrna cleavage,inhibition
clip
TarBase
URS000041FA2C
MRPS30
23313552
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000AD02D
MRPS30
21572407
25416803
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
NPM1
MRPS30
25348397
N/A
physical interaction
ComPPI
RPL36AL
MRPS30
25348397
N/A
physical interaction
ComPPI
FOXB1
MRPS30
24234451
25348397
25609649
association
physical interaction,tandem affinity purification
ComPPI,IntAct
MRPL28
MRPS30
25348397
N/A
physical interaction
ComPPI
MRM3
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL27
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL40
MRPS30
25348397
N/A
physical interaction
ComPPI
ZMYND19
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL23
MRPS30
25348397
N/A
physical interaction
ComPPI
C1QBP
MRPS30
25348397
N/A
physical interaction
ComPPI
CFTR
MRPS30
25348397
N/A
physical interaction
ComPPI
PDK1
MRPS30
24234451
25348397
29568061
association
proximity-dependent biotin identification
ComPPI,IntAct
PMPCA
MRPS30
25348397
N/A
physical interaction
ComPPI
CLPP
MRPS30
25348397
N/A
physical interaction
ComPPI
RPL6
MRPS30
25348397
N/A
physical interaction
ComPPI
RPL13
MRPS30
25348397
N/A
physical interaction
ComPPI
ELAC2
MRPS30
25348397
N/A
physical interaction
ComPPI
AURKAIP1
MRPS30
24234451
25348397
29568061
association
proximity-dependent biotin identification
ComPPI,IntAct
GADD45GIP1
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL17
MRPS30
25348397
N/A
physical interaction
ComPPI
HSPD1
MRPS30
24234451
25348397
29568061
association
physical interaction,proximity-dependent biotin identification
ComPPI,IntAct
SLC25A10
MRPS30
25348397
N/A
physical interaction
ComPPI
HNRNPA1
MRPS30
25348397
N/A
physical interaction
ComPPI
CYLD
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL42
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL44
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL20
MRPS30
25348397
N/A
physical interaction
ComPPI
GTPBP10
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL4
MRPS30
25348397
N/A
physical interaction
ComPPI
FGF8
MRPS30
25348397
N/A
physical interaction
ComPPI
SLC25A3
MRPS30
25348397
N/A
physical interaction
ComPPI
MGST3
MRPS30
24234451
25348397
29568061
association
proximity-dependent biotin identification
ComPPI,IntAct
MRPL12
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL9
MRPS30
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
MRPL38
MRPS30
25348397
N/A
physical interaction
ComPPI
VPS26B
MRPS30
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
MRPL19
MRPS30
25348397
N/A
physical interaction
ComPPI
MALSU1
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL43
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL10
MRPS30
25348397
N/A
physical interaction
ComPPI
ARMC8
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL39
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL45
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL53
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL37
MRPS30
25348397
N/A
physical interaction
ComPPI
TRMT61B
MRPS30
24234451
25348397
29568061
association
proximity-dependent biotin identification
ComPPI,IntAct
MRPL13
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL48
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL49
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL51
MRPS30
25348397
N/A
physical interaction
ComPPI
RPS8
MRPS30
25348397
N/A
physical interaction
ComPPI
SIRT4
MRPS30
24234451
25348397
25525879
association
anti tag coimmunoprecipitation
ComPPI,IntAct
MRPL58
MRPS30
20186120
24234451
25348397
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
DDX28
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL1
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL11
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL14
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL15
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL16
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL18
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL2
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL22
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL24
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL3
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL32
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL41
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL46
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL47
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPL50
MRPS30
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
MRPL55
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPS18A
MRPS30
25348397
N/A
physical interaction
ComPPI
MRPS30
MRPL57
25348397
N/A
physical interaction
ComPPI
MRPS30
RPL26L1
25348397
N/A
physical interaction
ComPPI
MRPS30
MRPL21
25348397
N/A
physical interaction
ComPPI
MRPS30
MRPL33
25348397
N/A
physical interaction
ComPPI
MRPS30
MRPL35
25348397
N/A
physical interaction
ComPPI
MRPS30
MRPL30
25348397
N/A
physical interaction
ComPPI
MRPS30
RBFOX3
25348397
N/A
physical interaction
ComPPI
MRPS30
TRUB2
25348397
N/A
physical interaction
ComPPI
MRPS30
MRPL34
25348397
N/A
physical interaction
ComPPI
MRPS30
MRPL52
25348397
N/A
physical interaction
ComPPI
MRPS30
FOXL1
24234451
25348397
25609649
association
physical interaction,tandem affinity purification
ComPPI,IntAct
MRPS30
MEX3C
25348397
N/A
physical interaction
ComPPI
HSCB
MRPS30
24234451
25348397
28380382
association
anti bait coimmunoprecipitation
ComPPI,IntAct
Source
Target
Pmid
Interactiontype
Methods
Database
URS00009B9D45
MRPS30
27087310
direct interaction,inhibition
N/A
NPInter
Visualization