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GENE：MRPS5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MRPS5
FullNmae mitochondrial ribosomal protein S5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14498
EnsembleID ENSG00000144029
Uniprot P82675

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MRPS5 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MRPS5 GO:0003723,GO:0003735,GO:0005739,GO:0005743,GO:0005743,GO:0005763,GO:0005763,GO:0005763,GO:0006412,GO:0032543

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MRPS5 hsa:64969 path:hsa03010 Ribosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 MRPS5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MRPS5 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 MRPS5 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MRPS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MRPS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MRPS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MRPS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MRPS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MRPS5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 MRPS5 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00003CF1AD MRPS5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000260A3A MRPS5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000038718E MRPS5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 MRPS5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A MRPS5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 MRPS5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 MRPS5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000039A25B MRPS5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F MRPS5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 MRPS5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE MRPS5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 MRPS5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 MRPS5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 MRPS5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 MRPS5 22100165 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TUFM MRPS5 25348397 N/A physical interaction ComPPI
JUN MRPS5 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
CUL3 MRPS5 25348397 N/A physical interaction ComPPI
DAP3 MRPS5 25348397 N/A physical interaction ComPPI
NTRK1 MRPS5 25348397 N/A physical interaction ComPPI
YBX1 MRPS5 22118625 24234451 25348397 association tandem affinity purification ComPPI,IntAct
PDGFB MRPS5 25348397 N/A physical interaction ComPPI
E4F1 MRPS5 25348397 N/A physical interaction ComPPI
C1QBP MRPS5 25348397 N/A physical interaction ComPPI
RPS6 MRPS5 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
H3C1 MRPS5 24234451 25348397 29568061 association pull down ComPPI,IntAct
CAND1 MRPS5 25348397 N/A physical interaction ComPPI
PDK1 MRPS5 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HNRNPR MRPS5 25348397 N/A physical interaction ComPPI
ESR2 MRPS5 21182203 24234451 25348397 association affinity chromatography technology ComPPI,IntAct
RPL6 MRPS5 25348397 N/A physical interaction ComPPI
RPL13 MRPS5 25348397 N/A physical interaction ComPPI
RPL23 MRPS5 25348397 N/A physical interaction ComPPI
EEF2 MRPS5 25348397 N/A physical interaction ComPPI
RBM42 MRPS5 25348397 N/A physical interaction ComPPI
AURKAIP1 MRPS5 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TRA2A MRPS5 25348397 N/A physical interaction ComPPI
LUC7L MRPS5 25348397 N/A physical interaction ComPPI
FLOT1 MRPS5 25348397 N/A physical interaction ComPPI
AGO1 MRPS5 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DDX56 MRPS5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPD1 MRPS5 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPS34 MRPS5 25348397 N/A physical interaction ComPPI
ILF3 MRPS5 25348397 N/A physical interaction ComPPI
HNRNPA1 MRPS5 25348397 N/A physical interaction ComPPI
PTCD3 MRPS5 25348397 N/A physical interaction ComPPI
FBL MRPS5 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
MRPS22 MRPS5 25348397 N/A physical interaction ComPPI
MRPS26 MRPS5 25348397 N/A physical interaction ComPPI
MRPS31 MRPS5 25348397 N/A physical interaction ComPPI
RPL17 MRPS5 25348397 N/A physical interaction ComPPI
SDHB MRPS5 25348397 N/A physical interaction ComPPI
TP53 MRPS5 25348397 N/A physical interaction ComPPI
NXF1 MRPS5 25348397 N/A physical interaction ComPPI
CCDC59 MRPS5 25348397 N/A physical interaction ComPPI
MRPS5 MRPL24 25348397 N/A physical interaction ComPPI
MRPS5 CORO1C 25348397 N/A physical interaction ComPPI
MRPS5 ZMPSTE24 25348397 N/A physical interaction ComPPI
MRPS5 MOV10 25348397 N/A physical interaction ComPPI
MRPS5 MRPS2 25348397 N/A physical interaction ComPPI
MRPS5 ZC3H3 25348397 N/A physical interaction ComPPI
MRPS5 RPS8 25348397 N/A physical interaction ComPPI
MRPS5 MRPS7 25348397 N/A physical interaction ComPPI
MRPS5 MRPS11 25348397 N/A physical interaction ComPPI
MRPS5 MRPS24 25348397 N/A physical interaction ComPPI
MRPS5 RPL18 25348397 N/A physical interaction ComPPI
TRMT61B MRPS5 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct

Source Target Pmid Interactiontype Methods Database
URS00009C4515 MRPS5 27087310 direct interaction,inhibition N/A NPInter

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