GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
MRRF
FullNmae
mitochondrial ribosome recycling factor
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:7234
EnsembleID
ENSG00000148187
Uniprot
Q96E11
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
MRRF
cuproptosis
36010978
Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1.
Cuproptosis-related genes
Go Annotation:
GeneSymbol
Go id
MRRF
GO:0005515,GO:0005739,GO:0005739,GO:0005759,GO:0006412,GO:0032790,GO:0043023
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
MRRF
UBB
23180781
24816145
ubiquitination reaction
ubiquitinase assay
InnateDB
Source
Target
Pmid
Interactiontype
Methods
Database
TFAP2C
MRRF
20629094
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
SMARCA4
MRRF
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F1
MRRF
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F4
MRRF
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
ETS1
MRRF
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOXA1
MRRF
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOS
MRRF
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
GATA2
MRRF
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
MITF
MRRF
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
TAL1
MRRF
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS000015A0D9
MRRF
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS00005D35D9
MRRF
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS00003E226A
MRRF
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS00005ACA7C
MRRF
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000AA464
MRRF
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000367985
MRRF
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000334286
MRRF
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS000017CCCB
MRRF
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000BB229
MRRF
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS00001DABC0
MRRF
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000B989F
MRRF
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS000032AE90
MRRF
23446348
25416803
mrna cleavage,inhibition
clip
TarBase
URS00003E5ECC
MRRF
23446348
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000085F64
MRRF
22927820
23313552
23824327
24906430
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS000076B539
MRRF
22927820
23313552
23824327
24906430
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS0000544FF1
MRRF
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000EEE35
MRRF
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000041E949
MRRF
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000346991
MRRF
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00002C02E4
MRRF
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000007F792
MRRF
23824327
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS0000148B91
MRRF
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000100748
MRRF
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000005A8ED
MRRF
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000C4DB5
MRRF
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00000AD002
MRRF
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00002578DA
MRRF
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000075C4B1
MRRF
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS0000308E4D
MRRF
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
ZNF408
MRRF
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
FHL3
MRRF
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
PPIB
MRRF
25348397
N/A
physical interaction
ComPPI
KRT40
MRRF
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
MKNK2
MRRF
25348397
N/A
physical interaction
ComPPI
TSFM
MRRF
25348397
N/A
physical interaction
ComPPI
SCP2
MRRF
25348397
N/A
physical interaction
ComPPI
SYP
MRRF
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
BANP
MRRF
25348397
N/A
physical interaction
ComPPI
RBMS1
MRRF
25348397
N/A
physical interaction
ComPPI
CLPP
MRRF
24234451
25348397
26058080
association
proximity-dependent biotin identification
ComPPI,IntAct
FBH1
MRRF
25348397
N/A
physical interaction
ComPPI
PPIF
MRRF
25348397
N/A
physical interaction
ComPPI
SARNP
MRRF
25348397
N/A
physical interaction
ComPPI
MED4
MRRF
25348397
N/A
physical interaction
ComPPI
MMAB
MRRF
25348397
N/A
physical interaction
ComPPI
SKA1
MRRF
25348397
N/A
physical interaction
ComPPI
TUBA1C
MRRF
25348397
N/A
physical interaction
ComPPI
NDUFA7
MRRF
25348397
N/A
physical interaction
ComPPI
SRPRB
MRRF
25348397
N/A
physical interaction
ComPPI
APP
MRRF
25348397
N/A
physical interaction
ComPPI
DBT
MRRF
25348397
N/A
physical interaction
ComPPI
RPS19
MRRF
25348397
N/A
physical interaction
ComPPI
SLIRP
MRRF
25348397
N/A
physical interaction
ComPPI
MRPL53
MRRF
25348397
N/A
physical interaction
ComPPI
ANAPC15
MRRF
25348397
N/A
physical interaction
ComPPI
MRPL58
MRRF
20186120
24234451
25348397
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
MRRF
CDV3
25348397
N/A
physical interaction
ComPPI
MRRF
NDUFA2
25348397
N/A
physical interaction
ComPPI
MRRF
HCCS
25348397
N/A
physical interaction
ComPPI
MRRF
NFS1
25348397
N/A
physical interaction
ComPPI
MRRF
LYRM7
25348397
N/A
physical interaction
ComPPI
MRRF
IBA57
25348397
N/A
physical interaction
ComPPI
MRRF
ARX
25348397
N/A
physical interaction
ComPPI
MRRF
CT55
25348397
N/A
physical interaction
ComPPI
MRRF
FAM9B
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
Visualization