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GENE：MTBP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MTBP
FullNmae MDM2 binding protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7417
EnsembleID ENSG00000172167
Uniprot Q96DY7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MTBP mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MTBP cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MTBP GO:0000776,GO:0000776,GO:0000785,GO:0007049,GO:0007089,GO:0008285,GO:0031396,GO:0034501,GO:0034501,GO:0045839

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MTBP hsa:27085 path:hsa04110 Cell cycle - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CEBPA MTBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MTBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MTBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MTBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CLK1 MTBP 25348397 N/A physical interaction ComPPI
MDM2 MTBP 10906133 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
EGFR MTBP 25348397 N/A physical interaction ComPPI
CDK8 MTBP 24234451 25348397 26496610 29568061 association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ZEB2 MTBP 24234451 25348397 26028330 association anti tag coimmunoprecipitation ComPPI,IntAct
CCNA2 MTBP 25348397 N/A physical interaction ComPPI

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