Gene Information gene info

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GENE：MTIF3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MTIF3
FullNmae mitochondrial translational initiation factor 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29788
EnsembleID ENSG00000122033
Uniprot Q9H2K0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MTIF3 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MTIF3 GO:0003743,GO:0005515,GO:0005739,GO:0005739,GO:0008135,GO:0032790,GO:0032790,GO:0043022,GO:0043024,GO:0070124,GO:0070124

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 MTIF3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MTIF3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C MTIF3 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 MTIF3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 MTIF3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 MTIF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 MTIF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MTIF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
IGF1R MTIF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MTIF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 MTIF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 MTIF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
TMEM11 MTIF3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BCL2L1 MTIF3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MTIF3 PAXIP1 25348397 N/A physical interaction ComPPI
MTIF3 MAPK1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MTIF3 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MTIF3 COQ8A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MTIF3 VAMP4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MTIF3 STX6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MTIF3 THBD 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MTIF3 TMEM97 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MTIF3 SCD 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MTIF3 LAPTM4B 25348397 N/A two hybrid ComPPI
MTIF3 ORMDL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MTIF3 SNX2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

Source Target Pmid Interactiontype Methods Database
URS00008BEDD2 MTIF3 27087310 direct interaction,inhibition N/A NPInter

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