Gene Information gene info

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GENE：MTO1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MTO1
FullNmae mitochondrial tRNA translation optimization 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19261
EnsembleID ENSG00000135297
Uniprot Q9Y2Z2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MTO1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MTO1 GO:0003723,GO:0005739,GO:0005829,GO:0030488,GO:0050660,GO:0070899

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 MTO1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 MTO1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MTO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MTO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MTO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 MTO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001A405B MTO1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C48FA MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F373E MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF MTO1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 MTO1 23313552 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003E2232 MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000031B6ED MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000086A4D MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000048D44E MTO1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 MTO1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000183BED MTO1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 MTO1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000028BB8 MTO1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001AFC71 MTO1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
LRP1 MTO1 25348397 N/A physical interaction ComPPI
DNAJC7 MTO1 25348397 N/A physical interaction ComPPI
SUV39H1 MTO1 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TENT5A MTO1 25348397 N/A physical interaction ComPPI
KDM1A MTO1 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
C4BPB MTO1 25348397 N/A physical interaction ComPPI
IL13RA2 MTO1 25348397 N/A physical interaction ComPPI
RABL2A MTO1 25348397 N/A physical interaction ComPPI
IARS2 MTO1 25348397 N/A physical interaction ComPPI
BBS7 MTO1 25348397 N/A physical interaction ComPPI
MTO1 CCNJL 25348397 N/A physical interaction ComPPI
MTO1 CRTAC1 25348397 N/A physical interaction ComPPI

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