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GENE：mTOR

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol mTOR
FullNmae mechanistic target of rapamycin kinase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3942
EnsembleID ENSG00000198793
Uniprot P42345

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MTOR immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MTOR autophagy 20526321 Here we show that mTOR signalling in rat kidney cells is inhibited during initiation of autophagy, but reactivated by prolonged starvation. retulator signature
MTOR autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
MTOR apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
mTOR cuproptosis 38330710 Some signaling pathways involved in copper homeostasis and lipid metabolism are closely related to the initiation and progression of tumors. mTOR regulates SREBP and other lipid metabolic regulators and effectors, and mTOR inhibitors can block the expression of genes associated with adipogenesis and prevent nuclear accumulation of SREBP. mTOR is also closely related to cuproptosis. regulator

Go Annotation:

GeneSymbol Go id
MTOR GO:0000139,GO:0001002,GO:0001003,GO:0001006,GO:0001156,GO:0001558,GO:0002296,GO:0003007,GO:0003179,GO:0004672,GO:0004674,GO:0004674,GO:0004674,GO:0004674,GO:0005515,GO:0005524,GO:0005634,GO:0005635,GO:0005654,GO:0005737,GO:0005741,GO:0005764,GO:0005764,GO:0005765,GO:0005765,GO:0005789,GO:0005829,GO:0005829,GO:0006112,GO:0006207,GO:0006468,GO:0006468,GO:0006468,GO:0006954,GO:0006974,GO:0007010,GO:0007040,GO:0007281,GO:0007584,GO:0008361,GO:0009267,GO:0009408,GO:0009791,GO:0010507,GO:0010507,GO:0010507,GO:0010507,GO:0010592,GO:0010628,GO:0010718,GO:0010831,GO:0012505,GO:0016020,GO:0016020,GO:0016236,GO:0016241,GO:0016242,GO:0016242,GO:0016301,GO:0016301,GO:0016310,GO:0016605,GO:0018105,GO:0018105,GO:0018105,GO:0019228,GO:0030163,GO:0030307,GO:0030425,GO:0030838,GO:0031295,GO:0031529,GO:0031641,GO:0031648,GO:0031667,GO:0031669,GO:0031669,GO:0031669,GO:0031670,GO:0031929,GO:0031929,GO:0031929,GO:0031931,GO:0031931,GO:0031931,GO:0031931,GO:0031932,GO:0031932,GO:0031932,GO:0032516,GO:0032869,GO:0032956,GO:0033173,GO:0034198,GO:0035264,GO:0038202,GO:0038202,GO:0042752,GO:0042802,GO:0043022,GO:0043066,GO:0043200,GO:0043276,GO:0045335,GO:0045670,GO:0045727,GO:0045792,GO:0045821,GO:0045945,GO:0045948,GO:0046777,GO:0046889,GO:0046889,GO:0048266,GO:0048511,GO:0048709,GO:0048714,GO:0050731,GO:0050882,GO:0051219,GO:0051496,GO:0051549,GO:0051647,GO:0051897,GO:0055013,GO:0060048,GO:0070885,GO:0071230,GO:0071233,GO:0071456,GO:0071456,GO:0071470,GO:0090559,GO:0106310,GO:1900034,GO:1900181,GO:1901796,GO:1901838,GO:1903691,GO:1904059,GO:1904690,GO:1905672,GO:1905857,GO:1990253,GO:2000785

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MTOR hsa:2475 path:hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human)
MTOR hsa:2475 path:hsa01522 Endocrine resistance - Homo sapiens (human)
MTOR hsa:2475 path:hsa04012 ErbB signaling pathway - Homo sapiens (human)
MTOR hsa:2475 path:hsa04066 HIF-1 signaling pathway - Homo sapiens (human)
MTOR hsa:2475 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
MTOR hsa:2475 path:hsa04136 Autophagy - other - Homo sapiens (human)
MTOR hsa:2475 path:hsa04140 Autophagy - animal - Homo sapiens (human)
MTOR hsa:2475 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
MTOR hsa:2475 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
MTOR hsa:2475 path:hsa04152 AMPK signaling pathway - Homo sapiens (human)
MTOR hsa:2475 path:hsa04211 Longevity regulating pathway - Homo sapiens (human)
MTOR hsa:2475 path:hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human)
MTOR hsa:2475 path:hsa04218 Cellular senescence - Homo sapiens (human)
MTOR hsa:2475 path:hsa04371 Apelin signaling pathway - Homo sapiens (human)
MTOR hsa:2475 path:hsa04613 Neutrophil extracellular trap formation - Homo sapiens (human)
MTOR hsa:2475 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)
MTOR hsa:2475 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)
MTOR hsa:2475 path:hsa04714 Thermogenesis - Homo sapiens (human)
MTOR hsa:2475 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
MTOR hsa:2475 path:hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)
MTOR hsa:2475 path:hsa04920 Adipocytokine signaling pathway - Homo sapiens (human)
MTOR hsa:2475 path:hsa04930 Type II diabetes mellitus - Homo sapiens (human)
MTOR hsa:2475 path:hsa04931 Insulin resistance - Homo sapiens (human)
MTOR hsa:2475 path:hsa04935 Growth hormone synthesis, secretion and action - Homo sapiens (human)
MTOR hsa:2475 path:hsa05010 Alzheimer disease - Homo sapiens (human)
MTOR hsa:2475 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
MTOR hsa:2475 path:hsa05016 Huntington disease - Homo sapiens (human)
MTOR hsa:2475 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
MTOR hsa:2475 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
MTOR hsa:2475 path:hsa05131 Shigellosis - Homo sapiens (human)
MTOR hsa:2475 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
MTOR hsa:2475 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
MTOR hsa:2475 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
MTOR hsa:2475 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
MTOR hsa:2475 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
MTOR hsa:2475 path:hsa05200 Pathways in cancer - Homo sapiens (human)
MTOR hsa:2475 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
MTOR hsa:2475 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)
MTOR hsa:2475 path:hsa05207 Chemical carcinogenesis - receptor activation - Homo sapiens (human)
MTOR hsa:2475 path:hsa05210 Colorectal cancer - Homo sapiens (human)
MTOR hsa:2475 path:hsa05212 Pancreatic cancer - Homo sapiens (human)
MTOR hsa:2475 path:hsa05214 Glioma - Homo sapiens (human)
MTOR hsa:2475 path:hsa05215 Prostate cancer - Homo sapiens (human)
MTOR hsa:2475 path:hsa05221 Acute myeloid leukemia - Homo sapiens (human)
MTOR hsa:2475 path:hsa05224 Breast cancer - Homo sapiens (human)
MTOR hsa:2475 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
MTOR hsa:2475 path:hsa05226 Gastric cancer - Homo sapiens (human)
MTOR hsa:2475 path:hsa05230 Central carbon metabolism in cancer - Homo sapiens (human)
MTOR hsa:2475 path:hsa05231 Choline metabolism in cancer - Homo sapiens (human)
MTOR hsa:2475 path:hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human)
MTOR hsa:2475 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MTOR DEPTOR 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16713974 17404308 17461779 17604271 17680028 18000759 18372248 18492954 19022819 19143635 19143636 19151919 19446321 19568798 19706736 19864431 20547845 20805416 21157483 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 26192618 27331412 28216025 interaction type N/A ACSN
MTOR MLST8 10702316 10722653 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15268862 15314020 15749884 15755954 15905173 16286006 16469695 16556040 16678438 16679021 16713974 16915281 17052453 17053147 17277771 17368478 17404308 17461779 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18481918 18492954 18566586 18570873 18614546 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20027184 20138985 20338997 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21533173 21621563 21708191 21981924 22504639 23087689 23180781 24795729 24973821 25002027 25682865 25730849 26159692 26192618 26597054 27328425 27331412 27510662 27572739 28216025 9069260 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
MTOR RPTOR 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15268862 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17277771 17368478 17386266 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 18519641 18614546 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 23180781 24795729 24973821 25002027 25682865 25730849 26159692 26192618 26597054 27328425 27331412 27510662 27572739 28216025 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
MTOR MAPKAP1 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17043309 17277771 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18614546 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 23180781 24795729 24973821 25002027 25730849 26159692 26192618 27331412 28216025 9069260 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
MTOR PRR5 12408816 12906785 16469695 17461779 17680028 18492954 18566586 19022819 19143635 19568798 21157483 21981924 23087689 23180781 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
MTOR RICTOR 10722653 11274345 11756498 12408816 12906785 15268862 16469695 16556040 16678438 17043309 17277771 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18614546 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 23180781 24795729 24973821 25002027 25730849 26159692 26192618 27331412 28216025 9069260 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
MTOR PPARGC1A 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
MTOR YY1 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
RAC1 MTOR 10702316 10722653 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16556040 16678438 16713974 17404308 17461779 17604271 17680028 18000759 18372248 18481918 18492954 18570873 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19720745 19864431 20027184 20138985 20338997 20547845 20805416 21157483 21474067 21533173 21621563 21708191 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 26192618 27331412 28216025 9069260 interaction type N/A ACSN
MTOR EIF4E 11108711 12150925 12408816 12709531 12844354 12867079 12906785 15314020 15755954 15905173 16286006 16469695 16679021 17368478 17680028 18391071 18492954 19022819 19339977 19568798 19597330 19864431 20647036 20932932 21157483 21177869 21233202 21981924 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26192618 28216025 interaction type N/A ACSN
MTOR EIF4B 12150925 12408816 12844354 12867079 12906785 15755954 15905173 16286006 16469695 16679021 17368478 17680028 18391071 18492954 19022819 19339977 19568798 19597330 19864431 20647036 21157483 21177869 21233202 21981924 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
MTOR RPS6 12150925 12408816 12844354 12867079 12906785 15755954 15905173 16286006 16469695 16679021 17368478 17680028 18391071 18492954 19022819 19339977 19568798 19597330 19864431 20647036 21157483 21177869 21233202 21981924 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
RHEB MTOR 12906785 15854902 15878852 16098514 16636147 17470430 17604271 18466115 18550814 19022819 19143635 20226003 21071413 23087689 23180781 23331499 26192618 interaction type,stimulation,physical association anti tag coimmunoprecipitation,pull down ACSN,InnateDB,SignaLink,SignaLink
MTOR FOXP3 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
SQSTM1 MTOR 15340068 16252010 20531300 21981924 25002027 26192618 26587781 28574505 interaction type N/A ACSN
MTOR MYC 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
MTOR MMP2 12150925 12408816 12906785 15755954 16469695 17680028 18492954 19022819 19568798 19864431 19930715 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 26192618 26597054 27328425 27510662 27572739 28216025 interaction type N/A ACSN
PTP4A3 MTOR 17409395 19440036 19945467 20609352 21084277 23691193 24030100 24376839 24696260 25136802 26192618 26597054 27328425 27572739 interaction type N/A ACSN
MTOR MMP9 12150925 12408816 12906785 15755954 16469695 17680028 18492954 19022819 19568798 19864431 19930715 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 26192618 26597054 27328425 27510662 27572739 28216025 interaction type N/A ACSN
PML MTOR 16915281 20452955 23180781 26192618 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
MTOR ESRRA 12150925 12408816 12533512 12906785 15755954 16314495 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
MTOR COX5A 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
MTOR IDH3A 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
MTOR GZMA 12150925 12408816 12906785 15749884 15755954 16469695 16713974 17404308 17604271 17680028 18372248 18492954 19022819 19143636 19446321 19568798 19706736 19864431 20547845 20805416 21157483 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
MTOR IL10 12150925 12408816 12906785 15749884 15755954 16469695 16713974 17404308 17604271 17680028 18372248 18492954 19022819 19143636 19446321 19568798 19706736 19864431 20547845 20805416 21157483 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
MTOR IFNG 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19143636 19446321 19568798 19706736 19864431 20805416 21157483 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
MTOR GZMB 12150925 12408816 12906785 15749884 15755954 16469695 16713974 17404308 17604271 17680028 18372248 18492954 19022819 19143636 19446321 19568798 19706736 19864431 20547845 20805416 21157483 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
MTOR AKT1 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 26192618 27331412 28216025 9812896 interaction type N/A ACSN
MTOR SGK1 10722653 11274345 11756498 12408816 12906785 16469695 17461779 17680028 18000759 18492954 18570873 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20338997 21157483 21474067 21981924 23087689 23180781 24795729 24973821 25002027 25730849 26159692 26192618 27331412 28216025 interaction type,phosphorylation reaction in-gel kinase assay ACSN,InnateDB
PRKCA MTOR 10679481 10871288 16492141 18851840 20027184 21474067 26192618 interaction type N/A ACSN
CUL1 MTOR 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18636226 18787170 18931676 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
RBX1 MTOR 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18636226 18787170 18931676 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
SKP1 MTOR 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18636226 18787170 18931676 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
MTOR ATG13 11274345 11756498 12150925 12408816 12906785 15755954 16469695 17680028 18000759 18492954 19022819 19151919 19225151 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 26192618 27331412 28216025 interaction type N/A ACSN
EIF4EBP1 MTOR 12150926 12604610 12747827 15066126 16824195 17517883 17693255 17991864 20537536 23180781 9465032 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay,protein kinase assay InnateDB
RICTOR MTOR 15268862 15467718 15718470 15809305 16603397 16919458 16962653 17277771 17461779 17545609 17599906 17604271 18030348 18339839 18411301 18505677 18566586 18570873 18614546 18925875 19114562 19145465 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,two hybrid,in-gel kinase assay,protein kinase assay InnateDB
RPTOR MTOR 12150925 12150926 12718876 15066126 15268862 15467718 15809305 16603397 16847060 16919458 16962653 17043309 17277771 17461779 17599906 17604271 18030348 18570873 18614546 18676370 19114562 19145465 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAPKAP1 MTOR 16919458 16962653 17277771 17461779 18030348 18566586 18570873 23180781 physical association anti tag coimmunoprecipitation InnateDB
FKBP8 MTOR 17991864 23180781 physical association anti tag coimmunoprecipitation InnateDB
PRR5 MTOR 17461779 17599906 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
PRR5L MTOR 17461779 18030348 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,pull down,in-gel kinase assay InnateDB
MLST8 MTOR 12718876 15066126 16919458 17277771 18030348 23180781 physical association anti tag coimmunoprecipitation InnateDB
AKT1S1 MTOR 17277771 17517883 17604271 18030348 18570873 19114562 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,pull down,in-gel kinase assay,protein kinase assay InnateDB
MTOR AKT1S1 17277771 17386266 23180781 physical association anti tag coimmunoprecipitation InnateDB
HSPA1B MTOR 18505677 23180781 physical association anti tag coimmunoprecipitation InnateDB
TSC2 MTOR 18411301 23180781 phosphorylation reaction protein kinase assay InnateDB
CLIP1 MTOR 12231510 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
GPHN MTOR 10325225 23180781 physical association pull down InnateDB
MTOR MTOR 10579915 10702316 10942774 12747827 16870609 17510057 17517883 19225151 19346248 19690328 19864431 21383122 21460634 22692423 23180781 26467481 9204908 9334222 9335553 9465032 phosphorylation reaction,physical association,up-regulates activity,down-regulates activity anti tag coimmunoprecipitation,in-gel kinase assay InnateDB,Signor
FKBP1A MTOR 23180781 9334222 physical association pull down InnateDB
YWHAQ MTOR 10664457 23180781 physical association anti tag coimmunoprecipitation InnateDB
PRKAR1A MTOR 16963469 23180781 physical association anti tag coimmunoprecipitation InnateDB
PRKCD MTOR 10698949 15952059 23180781 physical association anti tag coimmunoprecipitation InnateDB
RPS6KB1 MTOR 15760907 23180781 physical association anti tag coimmunoprecipitation InnateDB
MTOR TRAF2 14743216 23180781 physical association tandem affinity purification InnateDB
TELO2 MTOR 18160036 23180781 physical association anti tag coimmunoprecipitation InnateDB
STAT3 MTOR 10660304 15522880 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
IRS1 MTOR 15952059 23180781 physical association anti tag coimmunoprecipitation InnateDB
RRAGB MTOR 18497260 23180781 physical association anti tag coimmunoprecipitation InnateDB
MTOR RRAGC 18497260 23180781 physical association anti tag coimmunoprecipitation InnateDB
STAT1 MTOR 12807916 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF3B MTOR 16286006 23180781 physical association anti tag coimmunoprecipitation InnateDB
PREX1 MTOR 17565979 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
PREX2 MTOR 17565979 23180781 physical association anti tag coimmunoprecipitation InnateDB
RHEBL1 MTOR 16098514 23180781 physical association anti tag coimmunoprecipitation InnateDB
YWHAZ MTOR 15161933 23180781 physical association pull down InnateDB
MTOR ABL1 10753870 23180781 physical association anti tag coimmunoprecipitation InnateDB
UBQLN1 MTOR 11853878 23180781 physical association anti tag coimmunoprecipitation,two hybrid,pull down InnateDB
MTOR CHUK 18490760 18519641 23180781 physical association anti tag coimmunoprecipitation InnateDB
ATG13 MTOR 19211835 19225151 23180781 phosphorylation reaction in-gel kinase assay InnateDB
MTOR IKBKB 18519641 23180781 physical association anti tag coimmunoprecipitation InnateDB
ULK1 MTOR 19225151 23180781 phosphorylation reaction in-gel kinase assay InnateDB
ULK2 MTOR 19225151 23180781 phosphorylation reaction in-gel kinase assay InnateDB
DAP MTOR 20537536 23180781 phosphorylation reaction protein kinase assay InnateDB
SUZ12 MTOR 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
MTOR TERT 15843522 23180781 physical association anti tag coimmunoprecipitation InnateDB
ABL1 MTOR 10753870 21071413 23331499 stimulation N/A SignaLink,SignaLink
NOTCH1 MTOR 19265851 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AKT1S1 MTOR 20005715 interaction type N/A PSP
EIF4EBP1 MTOR 20005715 interaction type N/A PSP
IRS1 MTOR 20005715 interaction type N/A PSP
RPTOR MTOR 20005715 interaction type N/A PSP
TRAF2 MTOR 20005715 interaction type N/A PSP,SignaLink
YWHAQ MTOR 20005715 interaction type N/A PSP
YWHAZ MTOR 20005715 interaction type N/A PSP,SignaLink
RPTOR MTOR 12150925 12150925 12150926 12150926 12604610 12665511 12719976 15066126 15268862 15268862 15459249 15467718 16183647 16354680 16603397 16631613 16798736 16837165 16847060 16919458 17043309 17461779 20005715 20005715 20427287 21045808 21071413 N/A N/A SignaLink
YWHAQ MTOR 20005715 20005715 N/A N/A SignaLink
IRS1 MTOR 20005715 20005715 N/A N/A SignaLink
EIF4EBP1 MTOR 10971657 12150925 12150926 12747827 15854902 20005715 20005715 21071413 9465032 N/A N/A SignaLink
AKT1S1 MTOR 17277771 18988627 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR MTOR 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 MTOR 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 MTOR 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MTOR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MTOR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MTOR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MTOR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MTOR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MTOR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MTOR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC MTOR N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001A405B MTOR 23292834 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00002E92A8 MTOR 22983984 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000157026 MTOR 21383697 22299047 23292834 rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00001C308D MTOR 22299047 rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000157026 MTOR 21383697 21878637 22299047 22751686 23173671 23292834 23762265 23893385 24030073 24312487 24637915 24668416 24810364 25348507 25416803 27158364 28387375 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,chromatin immunoprecipitation assay,rna immunoprecipitation,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS0000508C13 MTOR 21898400 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001C308D MTOR 22299047 24668416 25416803 26259252 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00002E92A8 MTOR 22983984 25416803 26687302 27072960 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001A405B MTOR 23270926 23292834 23778488 24030073 25416803 26744318 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000EC1BE MTOR 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 MTOR 25311506 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000003BF62 MTOR 25416803 27097372 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000052E1A6 MTOR 25416803 26998071 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr TarBase
URS0000184017 MTOR 25416803 27315344 mrna cleavage,inhibition experimental interaction detection,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS0000367985 MTOR 24469061 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001F0C23 MTOR 25416803 26622553 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS000007D64A MTOR 25416803 26238185 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000049704B MTOR 25416803 27095304 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CHUK MTOR 22135298 phosphorylation N/A PhosphoSite
MTOR RPTOR 22135298 phosphorylation N/A PhosphoSite
MTOR EIF4EBP1 22135298 phosphorylation N/A PhosphoSite
MTOR ANKRD17 22135298 phosphorylation N/A PhosphoSite
MTOR EEF2K 22135298 phosphorylation N/A PhosphoSite
MTOR SRRM2 22135298 phosphorylation N/A PhosphoSite
MTOR MTOR 22135298 phosphorylation N/A PhosphoSite
MTOR ELL 22135298 phosphorylation N/A PhosphoSite
MTOR ULK1 22135298 phosphorylation N/A PhosphoSite
MTOR BRD9 22135298 phosphorylation N/A PhosphoSite
MTOR DEPTOR 22135298 phosphorylation N/A PhosphoSite
MTOR RPS6KB1 22135298 phosphorylation N/A PhosphoSite
MTOR ESR1 22135298 phosphorylation N/A PhosphoSite
MTOR WASHC2A 22135298 phosphorylation N/A PhosphoSite
MTOR TFEB 22135298 phosphorylation N/A PhosphoSite
MTOR SRRM1 22135298 phosphorylation N/A PhosphoSite
MTOR DAP 22135298 phosphorylation N/A PhosphoSite
MTOR BAG3 22135298 phosphorylation N/A PhosphoSite
MTOR RPRD1B 22135298 phosphorylation N/A PhosphoSite
MTOR PATL1 22135298 phosphorylation N/A PhosphoSite
MTOR GRB10 22135298 phosphorylation N/A PhosphoSite
MTOR UVRAG 22135298 phosphorylation N/A PhosphoSite
MTOR SGK1 22135298 phosphorylation N/A PhosphoSite
MTOR APBA3 22135298 phosphorylation N/A PhosphoSite
MTOR AKT1 22135298 phosphorylation N/A PhosphoSite
MTOR ZNRF2 22135298 phosphorylation N/A PhosphoSite
MTOR AKT1S1 22135298 phosphorylation N/A PhosphoSite
MTOR OXSR1 22135298 phosphorylation N/A PhosphoSite
MTOR ISCU 22135298 phosphorylation N/A PhosphoSite
MTOR LARP6 22135298 phosphorylation N/A PhosphoSite
MTOR DNMT1 22135298 phosphorylation N/A PhosphoSite
MTOR MYC 22135298 phosphorylation N/A PhosphoSite
MTOR MAPKAP1 22135298 phosphorylation N/A PhosphoSite
MTOR DUSP10 22135298 phosphorylation N/A PhosphoSite
MTOR AMBRA1 22135298 phosphorylation N/A PhosphoSite
MTOR HSF1 22135298 phosphorylation N/A PhosphoSite
MTOR UBR4 22135298 phosphorylation N/A PhosphoSite
MTOR LARP1 22135298 phosphorylation N/A PhosphoSite
MTOR ZNF768 22135298 phosphorylation N/A PhosphoSite
MTOR MAF1 22135298 phosphorylation N/A PhosphoSite
MTOR AMOTL2 22135298 phosphorylation N/A PhosphoSite
MTOR MYCN 22135298 phosphorylation N/A PhosphoSite
MTOR WNK1 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 MTOR 22135298 phosphorylation N/A PhosphoSite
AKT1 MTOR 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
SGTB MTOR 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TNFAIP3 MTOR 25348397 26043155 27898060 N/A physical interaction ComPPI,OmniPath
STAT1 MTOR 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
TRAF6 MTOR 25348397 N/A physical interaction ComPPI
VCP MTOR 25348397 N/A physical interaction ComPPI
FKBP1A MTOR 10089303 14525934 17148612 22664266 24234451 25348397 29997244 8662507 physical association beta galactosidase complementation,bioluminescence resonance energy transfer,biophysical,experimental interaction detection,molecular sieving,x-ray crystallography,physical interaction,biochemical,in vitro,luminescence based mammalian interactome mapping,proximity ligation assay ComPPI,HPRD,IntAct
LAMTOR4 MTOR 22980980 24234451 25348397 association cross-linking study ComPPI,IntAct
RACK1 MTOR 21376236 24234451 25348397 colocalization cosedimentation through density gradient ComPPI,IntAct
DPEP1 MTOR 25348397 N/A physical interaction ComPPI
BCL2L1 MTOR 25348397 N/A anti bait coimmunoprecipitation,anti bait coimmunoprecipitation,phosphorylation reaction,physical interaction,physical interaction,protein kinase assay ComPPI
MAPK8 MTOR 25348397 N/A physical interaction ComPPI
PRKCA MTOR 25348397 N/A physical interaction ComPPI
FBXW7 MTOR 25348397 N/A physical interaction ComPPI
PRKCD MTOR 25348397 N/A physical interaction ComPPI
PRKDC MTOR 24234451 24365180 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SUMO1 MTOR 25348397 N/A physical interaction ComPPI
EP300 MTOR 25348397 N/A physical interaction ComPPI
GSK3B MTOR 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDIA3 MTOR 25348397 N/A physical interaction ComPPI
YWHAZ MTOR 15161933 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
PRKAR1A MTOR 25348397 N/A physical interaction ComPPI
IRS2 MTOR 25348397 N/A physical interaction ComPPI
PRKAA1 MTOR 14525934 14970221 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PLD2 MTOR 14525934 16837165 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
RUVBL1 MTOR 20371770 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
BAG6 MTOR 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ILK MTOR 25348397 N/A physical interaction ComPPI
PDPK1 MTOR 11438723 14525934 24234451 25348397 physical association beta lactamase complementation,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
DIAPH1 MTOR 25348397 N/A physical interaction ComPPI
XPO6 MTOR 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
METAP2 MTOR 25348397 N/A physical interaction ComPPI
IKBKB MTOR 25348397 N/A physical interaction ComPPI
NFKBIA MTOR 25348397 N/A physical interaction ComPPI
RPS6KA1 MTOR 14525934 15905173 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
EIF4EBP1 MTOR 10364159 10779345 10942774 11438723 11691836 11777913 12105188 12150926 12665511 14525934 24234451 25348397 8083223 9092573 9405468 9465032 phosphorylation reaction experimental interaction detection,physical interaction,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
TERT MTOR 25348397 N/A physical interaction,in vivo ComPPI
PA2G4 MTOR 25348397 N/A physical interaction ComPPI
CFTR MTOR 25348397 N/A physical interaction ComPPI
SQSTM1 MTOR 25348397 N/A physical interaction ComPPI
STK38 MTOR 19875983 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3C MTOR 25348397 N/A physical interaction ComPPI
RAB1A MTOR 24234451 25348397 25446900 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,proximity ligation assay ComPPI,IntAct
EIF3F MTOR 14525934 16541103 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
RAP1A MTOR 25348397 N/A physical interaction ComPPI
RAP2A MTOR 25348397 N/A physical interaction ComPPI
XPO1 MTOR 25348397 N/A physical interaction ComPPI
YWHAQ MTOR 10664457 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TRAF2 MTOR 14743216 24234451 25241761 25348397 physical association physical interaction,tandem affinity purification,proximity ligation assay ComPPI,IntAct
RPS6 MTOR 25348397 N/A physical interaction ComPPI
RPS6KB1 MTOR 11279232 11914378 12604610 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SYNCRIP MTOR 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EGFR MTOR 25348397 N/A physical interaction ComPPI
SEPTIN2 MTOR 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HTT MTOR 25348397 N/A physical interaction ComPPI
IRS1 MTOR 11287630 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HSPA4 MTOR 25348397 N/A physical interaction ComPPI
SKP2 MTOR 25348397 N/A physical interaction ComPPI
GNB5 MTOR 25348397 N/A physical interaction ComPPI
PPP2R2A MTOR 25348397 N/A physical interaction ComPPI
RHEB MTOR 14525934 15854902 15878852 16098514 16631613 18550814 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CHUK MTOR 25348397 N/A physical interaction ComPPI
SIRT1 MTOR 21471201 24234451 25348397 phosphorylation reaction,association anti bait coimmunoprecipitation,physical interaction,protein kinase assay ComPPI,IntAct
RPL7 MTOR 21376236 24234451 25348397 colocalization cosedimentation through density gradient ComPPI,IntAct
PRKN MTOR 25348397 N/A physical interaction ComPPI
GNG2 MTOR 25348397 N/A physical interaction ComPPI
GPHN MTOR 10325225 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
VIPR2 MTOR 25348397 N/A physical interaction ComPPI
PDK1 MTOR 25348397 N/A physical interaction ComPPI
RP2 MTOR 25348397 N/A physical interaction ComPPI
CDC37 MTOR 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CD244 MTOR 25348397 N/A physical interaction ComPPI
FKBP8 MTOR 25348397 N/A physical interaction ComPPI
SGK1 MTOR 24234451 25348397 27451907 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL5 MTOR 25348397 N/A physical interaction ComPPI
XPO4 MTOR 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CD274 MTOR 25348397 N/A physical interaction ComPPI
TRIM25 MTOR 25348397 N/A physical interaction ComPPI
NCBP1 MTOR 18423201 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBQLN1 MTOR 11853878 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
DDB1 MTOR 25348397 N/A physical interaction ComPPI
NBN MTOR 25348397 N/A physical interaction ComPPI
GTF3C2 MTOR 20543138 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TERF1 MTOR 25348397 N/A physical interaction ComPPI
HTR6 MTOR 25348397 N/A physical interaction ComPPI
ESR1 MTOR 25348397 N/A physical interaction ComPPI
HNRNPD MTOR 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GNB2 MTOR 25348397 N/A physical interaction ComPPI
MTOR RPS6KB2 11733037 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MTOR MLST8 12408816 12718876 14525934 15066126 17461779 20562859 24234451 25348397 26348909 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,molecular sieving,x-ray crystallography,physical interaction,ion exchange chromatography,in vivo,inference by socio-affinity scoring ComPPI,HPRD,IntAct
MTOR RICTOR 14525934 15718470 16221682 16603397 17461779 17565979 18339839 18566587 19446321 19875983 21045808 21376236 22307628 23263282 23953116 24036451 24234451 24375676 25348397 27043084 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cosedimentation through density gradient,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
MTOR RHEBL1 14525934 16098514 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
MTOR AKT1S1 19446321 23953116 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct
MTOR RPTOR 12150925 12150926 12408816 14525934 15066126 16354680 1683716516603397 17461779 17565979 18955708 19446321 19619545 19875983 21045808 21614075 22424946 23263282 23953116 24036451 24234451 24375676 25348397 25446900 26348909 26678875 27043084 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cosedimentation through density gradient,experimental interaction detection,light scattering,molecular sieving,x-ray crystallography,physical interaction,electron tomography,in vitro,in vivo,proximity ligation assay,solid phase assay ComPPI,HPRD,IntAct
MTOR STAT3 14525934 15522880 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MTOR AKT1 10910062 11438723 14525934 24234451 24670654 25241761 25348397 phosphorylation reaction,physical association anti tag coimmunoprecipitation,beta lactamase complementation,experimental interaction detection,phosphorylation reaction,physical interaction,protein kinase assay,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
MTOR ABL1 25348397 N/A physical interaction ComPPI
MTOR LRPAP1 25348397 N/A physical interaction ComPPI
MTOR CLIP1 12231510 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
MTOR EIF3B 18423201 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR MAPKAP1 17461779 18566587 19875983 21045808 21376236 24234451 24365180 25348397 colocalization,association anti bait coimmunoprecipitation,cosedimentation through density gradient,physical interaction ComPPI,IntAct
MTOR CFP 25348397 N/A physical interaction ComPPI
MTOR TTI1 20810650 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR TELO2 18160036 20801936 24234451 25348397 association affinity chromatography technology,anti bait coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
MTOR DEPTOR 19446321 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR PRR5 17461779 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR RPL23A 25348397 N/A physical interaction ComPPI
MTOR RPL26 21376236 24234451 25348397 colocalization,association anti bait coimmunoprecipitation,cosedimentation through density gradient,physical interaction ComPPI,IntAct
MTOR C7ORF25 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MTOR SIRT7 25348397 N/A physical interaction ComPPI
MTOR USP9X 25348397 N/A physical interaction ComPPI
MTOR RUVBL2 25348397 N/A physical interaction ComPPI
MTOR RRAGC 24234451 25348397 25446900 physical association physical interaction,proximity ligation assay ComPPI,IntAct
MTOR ULK1 23524951 24234451 25348397 25686248 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR RRAGD 25348397 N/A physical interaction ComPPI
MTOR PML 25348397 N/A physical interaction ComPPI
MTOR BRCA1 25348397 N/A physical interaction ComPPI
MTOR TP53 19619545 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR PREX1 17565979 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
MTOR PREX2 25348397 N/A pull down,physical interaction ComPPI
MTOR LARS1 22424946 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR AMBRA1 25348397 N/A physical interaction ComPPI
MTOR MTA2 25348397 N/A physical interaction ComPPI
MTOR GNB1 24462769 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MTOR GNB3 25348397 N/A physical interaction ComPPI
MTOR RRAGB 25348397 N/A physical interaction ComPPI
MTOR PRR5L 17461779 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR EIF4E 18423201 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR IKBKG 25348397 N/A physical interaction ComPPI
MTOR GADD45A 25348397 N/A physical interaction ComPPI
MTOR SHMT2 25348397 N/A physical interaction ComPPI
MTOR MOV10 25348397 N/A physical interaction ComPPI
MTOR NXF1 25348397 N/A physical interaction ComPPI
MTOR MAF1 20543138 24234451 25348397 phosphorylation reaction phosphorylation reaction,physical interaction,protein kinase assay ComPPI,IntAct
MTOR LAMTOR2 22980980 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
MTOR SUZ12 25348397 N/A physical interaction ComPPI
MTOR GTF3C1 25348397 N/A physical interaction ComPPI
MTOR BSG 25348397 N/A physical interaction ComPPI
MTOR VSIG2 25348397 N/A physical interaction ComPPI
MTOR CA14 25348397 N/A physical interaction ComPPI
MTOR NT5E 25348397 N/A physical interaction ComPPI
MTOR LYPD3 25348397 N/A physical interaction ComPPI
MTOR SCN2B 25348397 N/A physical interaction ComPPI
MTOR MLXIP 25348397 N/A physical interaction ComPPI
MTOR MLXIPL 25348397 N/A physical interaction ComPPI
MTOR TRMT61A 25348397 N/A physical interaction ComPPI
MTOR LLGL2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR YEATS4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR VPS16 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR NAF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR ASPM 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR ZSCAN26 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR BRAT1 25348397 N/A physical interaction ComPPI
MTOR MAP3K3 25348397 N/A physical interaction ComPPI
MTOR DCP2 25348397 N/A physical interaction ComPPI
MTOR MTMR3 24234451 25348397 26787466 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR ZNRF2 25348397 N/A physical interaction ComPPI
MTOR FBXO8 25348397 N/A physical interaction ComPPI
MTOR LEFTY1 25348397 N/A physical interaction ComPPI
MTOR SCN3B 25348397 N/A physical interaction ComPPI
MTOR NTRK3 25348397 N/A physical interaction ComPPI
MTOR NPY2R 25348397 N/A physical interaction ComPPI
MTOR CD83 25348397 N/A physical interaction ComPPI
MTOR PACC1 25348397 N/A physical interaction ComPPI
MTOR THADA 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MTOR SMDT1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MTOR ZUP1 25348397 N/A physical interaction ComPPI
MTOR GTF3C5 20543138 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR FBXO9 23263282 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR RPS9 17461779 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MTOR ARHGAP8 25348397 N/A anti tag coimmunoprecipitation ComPPI
MTOR RPS16 21376236 24234451 25348397 colocalization cosedimentation through density gradient ComPPI,IntAct
MTOR LAMTOR1 22980980 24234451 25348397 association cross-linking study ComPPI,IntAct
MTOR LAMTOR5 22980980 24234451 25348397 association cross-linking study ComPPI,IntAct
MTOR TPCN2 23394946 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
MTOR TPCN1 23394946 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
MTOR PIH1D1 24036451 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RPL23 MTOR 25348397 N/A physical interaction ComPPI
EIF4EBP2 MTOR 25348397 N/A physical interaction ComPPI
MTOR MTOR 10702316 11438723 12030785 14525934 16870609 24234451 24670654 phosphorylation reaction,physical association beta lactamase complementation,experimental interaction detection,protein kinase assay HPRD,IntAct
CLN6 MTOR 24234451 30177828 association anti tag coimmunoprecipitation IntAct
MTOR FKBP1A 10089303 15268862 15284440 15467718 15796538 17145710 17991864 26344197 27898060 7822316 8662507 9334222 N/A N/A OmniPath
FKBP1A MTOR 10089303 15268862 15284440 15467718 15796538 17145710 17991864 26344197 27898060 7822316 8662507 9334222 inhibition N/A OmniPath
MTOR GPHN 10325225 27898060 N/A N/A OmniPath
GPHN MTOR 10325225 27898060 N/A N/A OmniPath
PRKCD MTOR 10698949 15952059 27898060 N/A N/A OmniPath
CHUK MTOR 18490760 18519641 27898060 N/A N/A OmniPath
MTOR CHUK 18490760 18519641 27898060 N/A N/A OmniPath
MTOR TRAF2 14743216 25241761 27898060 N/A N/A OmniPath
TRAF2 MTOR 14743216 25241761 27898060 stimulant N/A OmniPath
MTOR DNMT1 26351843 27898060 N/A N/A OmniPath
MTOR AKT1S1 17277771 17386266 17510057 17517883 17604271 18030348 18372248 18570873 19114562 19446321 27898060 inhibition N/A OmniPath
AKT1S1 MTOR 17277771 17386266 17510057 17517883 17604271 18030348 18372248 18570873 19114562 19446321 27898060 inhibition N/A OmniPath
MTOR DAP 16602700 17081983 18669648 20537536 27898060 stimulant N/A OmniPath
RPS6KA1 MTOR 10910062 15905173 18691976 19664994 27898060 N/A N/A OmniPath
ULK1 MTOR 19225151 19690328 21460630 25686248 27898060 N/A N/A OmniPath
MTOR ULK1 10995454 17595159 19225151 19690328 21258367 21383122 21460630 21460634 25126726 25499913 25686248 27898060 inhibition N/A OmniPath
MTOR ATG13 19211835 19211837 19225151 19258318 27898060 inhibition N/A OmniPath
MTOR MLST8 12408816 12718876 12719976 15066126 15268862 15459249 16183647 16798736 16919458 17277771 17461779 18030348 18505677 18614546 18851840 19446321 20427287 20562859 20801936 21321085 22084251 22258093 23636326 26186194 27898060 N/A N/A OmniPath
MLST8 MTOR 12408816 12718876 12719976 15066126 15268862 15459249 16183647 16798736 16919458 17277771 17461779 18030348 18505677 18614546 18851840 19446321 20427287 20562859 20801936 21321085 22084251 22258093 23636326 26186194 27898060 stimulant N/A OmniPath
AKT1 MTOR 10567225 10910062 11438723 14970221 15388791 15625077 15718470 15829723 15899889 15905173 18505677 18566586 18566587 18691976 19079619 19244117 19664994 20153512 20484036 21045808 21157483 21177249 21343617 21592956 21602892 22084251 23172666 23872070 25241761 27898060 inhibition,stimulant N/A OmniPath
MTOR AKT1 10910062 11438723 14761976 14970221 15047712 15718470 15829723 17013611 18505677 18566586 18566587 20333297 21045808 21157483 21177249 21343617 21592956 22084251 23872070 25241761 27898060 8978681 9736715 stimulant N/A OmniPath
IRS1 MTOR 11287630 15952059 16354680 27898060 N/A N/A OmniPath
MTOR IRS1 11287630 15952059 16354680 27898060 9335553 inhibition N/A OmniPath
PML MTOR 16915281 27898060 N/A N/A OmniPath
MTOR RICTOR 15268862 15467718 15718470 15809305 16183647 16221682 16603397 16919458 16962653 17043309 17277771 17386266 17461779 17545609 17565979 17599906 17604271 18030348 18339839 18411301 18505677 18566586 18566587 18570873 18614546 18664580 18851840 18925875 19114562 19145465 19446321 19619545 19875983 20427287 20801936 20978191 21045808 21177249 21321085 21343617 21376236 22084251 22285861 22544753 22990118 23297343 23872070 23953116 24375676 25897075 27898060 N/A N/A OmniPath
RICTOR MTOR 15268862 15467718 15718470 15809305 16183647 16221682 16603397 16919458 16962653 17043309 17277771 17386266 17461779 17545609 17565979 17599906 17604271 18030348 18339839 18411301 18505677 18566586 18566587 18570873 18614546 18664580 18851840 18925875 19114562 19145465 19446321 19619545 19875983 20427287 20801936 20978191 21045808 21177249 21321085 21343617 21376236 22084251 22285861 22544753 22990118 23297343 23872070 23953116 24375676 25897075 27898060 N/A N/A OmniPath
YWHAZ MTOR 15161933 27898060 N/A N/A OmniPath
MTOR RHEB 15772076 15854902 15878852 16098514 16631613 16915281 17470430 18075516 18550814 20006481 27898060 N/A N/A OmniPath
RHEB MTOR 15772076 15854902 15878852 16098514 16631613 16915281 17470430 18075516 18550814 20006481 27898060 stimulant N/A OmniPath
STAT1 MTOR 12807916 19553685 25241761 27898060 N/A N/A OmniPath
MTOR STAT1 12807916 19553685 25241761 27898060 N/A N/A OmniPath
MTOR AMBRA1 23524951 27898060 N/A N/A OmniPath
MTOR EIF4EBP1 10364159 10471835 10779345 10942774 10971657 11410517 11438723 11553333 11691836 11777913 11799119 12105188 12150925 12150926 12271141 12370290 12588975 12604610 12665511 12747827 12912989 15066126 15459249 15767663 15854902 16288292 16339216 16354698 16798736 16824195 17287340 17386266 17487921 17510057 17517883 17693255 17991864 18030348 18056483 18220336 18337751 18669648 18722121 18767875 18955708 19413330 19651622 19664995 19690332 19804365 20068231 20537536 20616057 21460630 22071574 25686248 25702871 25762619 26170285 27898060 8083223 8895571 9092573 9204908 9405468 9465032 9826548 inhibition,stimulant N/A OmniPath
MTOR JAK1 15659558 27898060 N/A N/A OmniPath
PIK3CA MTOR 18721898 27898060 stimulant N/A OmniPath
SUZ12 MTOR 24457600 27898060 N/A N/A OmniPath
ABL1 MTOR 10753870 27898060 inhibition,stimulant N/A OmniPath
MTOR HSF1 15760475 22496356 22768106 24126052 24516381 24589236 24746225 24954509 25024384 25406061 25728673 25752395 25963659 26010766 26359349 27898060 N/A N/A OmniPath
MTOR HDAC1 11602581 27898060 N/A N/A OmniPath
MTOR EIF4EBP3 14967450 16288292 27898060 inhibition,stimulant N/A OmniPath
MTOR GRB10 15952796 21659604 27898060 stimulant N/A OmniPath
MTOR ULK2 19211836 19225151 27898060 inhibition N/A OmniPath
MTOR MYCN 19111882 25100564 27898060 N/A N/A OmniPath
TSC2 MTOR 12271141 18411301 27898060 inhibition,stimulant N/A OmniPath
MTOR EIF4EBP2 14967450 16288292 23100465 27898060 inhibition,stimulant N/A OmniPath
MAPK1 MTOR 10910062 27898060 N/A N/A OmniPath
SGK1 MTOR 18570873 20338997 27898060 N/A N/A OmniPath
MTOR SGK1 10191262 11096081 11832334 11956329 12023960 15461589 16982696 18456663 18570873 18925875 19232516 20110348 20338997 20832730 25384981 25797247 25918246 27898060 9764820 stimulant N/A OmniPath
NOTCH1 MTOR 19265851 27898060 stimulant N/A OmniPath
MTOR MAF1 17081983 18669648 19690332 20233713 20516213 20543138 27898060 inhibition N/A OmniPath
MTOR RPS6KA2 15060135 27898060 stimulant N/A OmniPath
MTOR RPTOR 12150925 12150926 12408816 12665511 12718876 12719976 12747827 15066126 15268862 15459249 15467718 15661536 15809305 16183647 16354680 16603397 16631613 16798736 16837165 1683716516603397 16847060 16919458 16962653 17043309 17277771 17386266 17461779 17565979 17599906 17604271 18030348 18505677 18519641 18570873 18614546 18664580 18676370 18722121 18851840 18955708 19114562 19145465 19346248 19446321 19619545 19864431 19875983 20169205 20381137 20427287 20801936 21045808 21071439 21177249 21321085 22258093 22356909 22424946 22493283 22544753 23297343 23872070 23911927 23953116 24337580 24375676 24403073 24516643 25007995 25332233 25446900 27898060 stimulant N/A OmniPath
RPTOR MTOR 12150925 12150926 12408816 12665511 12718876 12719976 12747827 15066126 15268862 15459249 15467718 15661536 15809305 16183647 16354680 16603397 16631613 16798736 16837165 1683716516603397 16847060 16919458 16962653 17043309 17277771 17386266 17461779 17565979 17599906 17604271 18030348 18505677 18519641 18570873 18614546 18664580 18676370 18722121 18851840 18955708 19114562 19145465 19346248 19446321 19619545 19864431 19875983 20169205 20381137 20427287 20801936 21045808 21071439 21177249 21321085 22258093 22356909 22424946 22493283 22544753 23297343 23872070 23911927 23953116 24337580 24375676 24403073 24516643 25007995 25332233 25446900 27898060 inhibition,stimulant N/A OmniPath
AKT2 MTOR 12782654 27898060 stimulant N/A OmniPath
MTOR PREX2 17565979 27898060 N/A N/A OmniPath
MTOR TELO2 18160036 20801936 27898060 N/A N/A OmniPath
TELO2 MTOR 18160036 20801936 27898060 stimulant N/A OmniPath
MTOR STAT3 10660304 15522880 16740698 18691976 23329839 27898060 stimulant N/A OmniPath
FKBP8 MTOR 17991864 27898060 inhibition N/A OmniPath
RPS6KB1 MTOR 10567225 10567431 10579915 10910062 10971657 11279232 11914378 12023960 12150925 12150926 12370290 12586835 12604610 12718876 12782654 12807916 14560963 14679009 15066126 15388791 15718470 15760907 15809305 15854902 15896331 15899889 15905173 16099428 16183647 16922504 17386266 18505677 18669648 18691976 19664994 20068231 22544753 27898060 9271440 9465032 stimulant N/A OmniPath
MTOR RPS6KB1 10567225 10567431 10579915 10910062 10971657 11279232 11500364 11914378 12023960 12150925 12150926 12370290 12586835 12604610 12718876 12782654 12807916 14560963 14679009 15066126 15388791 15718470 15760907 15809305 15854902 15896331 15899889 15905173 16099428 16183647 16922504 17386266 18326039 18505677 18669648 18691976 19570988 19664994 20068231 22544753 25936802 27898060 9271440 9465032 stimulant N/A OmniPath
MTOR YWHAQ 10664457 27898060 N/A N/A OmniPath
TSC1 MTOR 12271141 27898060 inhibition,stimulant N/A OmniPath
MTOR IKBKB 18490760 18519641 27898060 N/A N/A OmniPath
MTOR UVRAG 25533187 26139536 27898060 N/A N/A OmniPath
MTOR DUSP10 25568665 27898060 N/A N/A OmniPath
MTOR RHEBL1 16098514 27898060 N/A N/A OmniPath
RRAGC MTOR 18497260 21981924 24337580 25446900 27898060 inhibition N/A OmniPath
RRAGB MTOR 18497260 24337580 27898060 inhibition N/A OmniPath
MTOR APBA3 24164895 27898060 N/A N/A OmniPath
PRKAR1A MTOR 16963469 27898060 N/A N/A OmniPath
MTOR UBQLN1 11853878 27898060 N/A N/A OmniPath
UBQLN1 MTOR 11853878 27898060 N/A N/A OmniPath
MTOR WAS 12769847 27898060 N/A N/A OmniPath
EIF3B MTOR 16286006 18423201 21045808 27898060 N/A N/A OmniPath
PREX1 MTOR 17565979 27898060 N/A N/A OmniPath
MTOR RPS6KB2 11733037 11914378 14560963 17510057 23486913 27898060 stimulant N/A OmniPath
MTOR CLIP1 12231510 27898060 stimulant N/A OmniPath
MTOR PRR5L 17461779 18030348 27898060 N/A N/A OmniPath
PRR5L MTOR 17461779 18030348 27898060 N/A N/A OmniPath
MTOR MAPKAP1 16919458 16962653 17043309 17277771 17461779 18030348 18505677 18566586 18570873 18614546 18851840 19875983 21045808 21177249 22084251 27898060 N/A N/A OmniPath
PRR5 MTOR 17461779 17599906 18505677 27898060 N/A N/A OmniPath
MTOR TFEB 22343943 22692423 27898060 inhibition N/A OmniPath
RAG1 MTOR 22790199 27898060 stimulant N/A OmniPath
MTOR DEPTOR 19446321 22017875 22017877 27898060 inhibition N/A OmniPath
DEPTOR MTOR 19446321 22017875 22017877 27898060 inhibition N/A OmniPath
RAG2 MTOR 22790199 27898060 stimulant N/A OmniPath
MTMR3 MTOR 26787466 27898060 inhibition N/A OmniPath
MTOR ISCU 23508953 27898060 stimulant N/A OmniPath

Visualization










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