Gene Information gene info

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GENE：NAPA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NAPA
FullNmae NSF attachment protein alpha
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7641
EnsembleID ENSG00000105402
Uniprot P54920

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NAPA cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
NAPA GO:0000149,GO:0005483,GO:0005515,GO:0005829,GO:0005886,GO:0006886,GO:0006891,GO:0007420,GO:0010807,GO:0016020,GO:0016082,GO:0019905,GO:0030182,GO:0035249,GO:0035494,GO:0044877,GO:0045176,GO:0061025,GO:0070044,GO:0070062,GO:0098793,GO:0098978

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NAPA hsa:8775 path:hsa04721 Synaptic vesicle cycle - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IL7R NAPA 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB
STX4 NAPA 16189514 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
AR NAPA 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 NAPA 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TP63 NAPA 17521434 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 NAPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NAPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NAPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NAPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 NAPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NAPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NAPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NAPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 NAPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 NAPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 NAPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
STX1A NAPA 25361965 interaction type N/A PTMCode2
NAPA STX1A 25361965 interaction type N/A PTMCode2
GOSR1 NAPA 25361965 interaction type N/A PTMCode2
NAPA GOSR1 25361965 interaction type N/A PTMCode2
NAPA VAMP8 25361965 interaction type N/A PTMCode2
VAMP8 NAPA 25361965 interaction type N/A PTMCode2
NAPA GNA12 25361965 interaction type N/A PTMCode2
GNA12 NAPA 25361965 interaction type N/A PTMCode2
NAPA STX5 25361965 interaction type N/A PTMCode2
STX5 NAPA 25361965 interaction type N/A PTMCode2
NAPA STX4 25361965 interaction type N/A PTMCode2
STX4 NAPA 25361965 interaction type N/A PTMCode2
NAPA NSF 25361965 interaction type N/A PTMCode2
NSF NAPA 25361965 interaction type N/A PTMCode2
STX6 NAPA 25361965 interaction type N/A PTMCode2
NAPA STX6 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNAP29 NAPA 25348397 N/A physical interaction ComPPI
VAMP2 NAPA 25348397 N/A physical interaction ComPPI
STX12 NAPA 14525934 25348397 26186194 27898060 9507000 9817754 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
VCP NAPA 25348397 N/A physical interaction ComPPI
RINT1 NAPA 25348397 N/A physical interaction ComPPI
TRPC3 NAPA 14525934 15327778 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
CANX NAPA 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RPA1 NAPA 25348397 N/A physical interaction ComPPI
STAM2 NAPA 25348397 N/A physical interaction ComPPI
HNRNPL NAPA 25348397 N/A physical interaction ComPPI
SNAP25 NAPA 25348397 N/A physical interaction ComPPI
SNAP23 NAPA 14525934 16189514 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid pooling approach,two hybrid ComPPI,HPRD,IntAct
AP2A2 NAPA 25348397 N/A physical interaction ComPPI
STX4 NAPA 14525934 16189514 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid pooling approach,two hybrid ComPPI,HPRD,IntAct
RPA2 NAPA 25348397 N/A physical interaction ComPPI
RPA3 NAPA 25348397 N/A physical interaction ComPPI
UNC45A NAPA 25348397 N/A physical interaction ComPPI
NSF NAPA 14525934 15322554 20562859 24234451 25348397 27898060 7622514 9362506 physical association anti tag coimmunoprecipitation,experimental interaction detection,chromatography technology,physical interaction,in vivo ComPPI,HPRD,IntAct,OmniPath
STX1A NAPA 14525934 25348397 7622514 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
VAMP8 NAPA 14525934 25348397 27898060 9614193 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
NAPA STX7 14525934 25348397 26186194 27898060 9417091 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
NAPA GOSR2 14525934 25348397 27898060 9349823 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
NAPA GOSR1 25348397 N/A in vitro,in vivo ComPPI
NAPA BNIP1 14525934 15272311 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
NAPA STX5 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NAPA RTN4 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NAPA APP 25348397 N/A physical interaction ComPPI
NAPA DHX40 25348397 N/A physical interaction ComPPI
NAPA THUMPD3 25348397 N/A physical interaction ComPPI
NAPA DHX29 25348397 N/A physical interaction ComPPI
NAPA FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
NAPA VCAM1 19738201 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
NAPA ITGA4 25348397 N/A physical interaction ComPPI
NAPA ATP4A 25348397 N/A physical interaction ComPPI
NAPA RNF2 25348397 N/A physical interaction ComPPI
NAPA VTI1B 25348397 N/A physical interaction ComPPI
NAPA STX6 25348397 N/A physical interaction ComPPI
NAPA USE1 25348397 N/A physical interaction ComPPI
NAPA NAPG 25348397 N/A physical interaction ComPPI
NAPA TMEM171 25348397 N/A physical interaction ComPPI
NAPA SLC30A4 25348397 N/A physical interaction ComPPI
NAPA HSPB1 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
NAPA BET1 24234451 25348397 29568061 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NAPA HSPA4L 25348397 N/A physical interaction ComPPI
NAPA HYOU1 25348397 N/A physical interaction ComPPI
NAPA CAPZB 25348397 N/A physical interaction ComPPI
NAPA STX16 25348397 N/A physical interaction ComPPI
NAPA TRMT6 25348397 N/A physical interaction ComPPI
NAPA VAMP4 25348397 N/A physical interaction ComPPI
NAPA SEC22B 25348397 N/A physical interaction ComPPI
NAPA STXBP6 25348397 N/A physical interaction ComPPI
NAPA IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NAPA BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
NAPA KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
NAPA PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
NAPA OCRL 24234451 25107275 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NAPA RAB9A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NAPA TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
STX8 NAPA 10683148 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ATP6V1B2 NAPA 25348397 N/A physical interaction ComPPI
NAPA GNA12 14525934 15980433 27898060 N/A experimental interaction detection,two hybrid HPRD,OmniPath
IL7R NAPA 20167604 27898060 N/A N/A OmniPath

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