Gene Information gene info

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GENE：NARS2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NARS2
FullNmae asparaginyl-tRNA synthetase 2, mitochondrial
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26274
EnsembleID ENSG00000137513
Uniprot Q96I59

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NARS2 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
NARS2 GO:0003676,GO:0004816,GO:0004816,GO:0005524,GO:0005654,GO:0005739,GO:0005739,GO:0005739,GO:0005759,GO:0005829,GO:0006421,GO:0006421

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NARS2 hsa:79731 path:hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR NARS2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 NARS2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 NARS2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 NARS2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 NARS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NARS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NARS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NARS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NARS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 NARS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NARS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NARS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 NARS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 NARS2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 NARS2 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase

Source Target Pmid Interactiontype Methods Database
CHCHD2 NARS2 25348397 N/A physical interaction ComPPI
ISG15 NARS2 24234451 25348397 26259872 association pull down ComPPI,IntAct
RAB8B NARS2 25348397 N/A physical interaction ComPPI
GRK2 NARS2 25348397 N/A physical interaction ComPPI
CD70 NARS2 25348397 N/A physical interaction ComPPI
PDK1 NARS2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PDK4 NARS2 25348397 N/A physical interaction ComPPI
CLPP NARS2 24234451 25348397 26058080 association proximity-dependent biotin identification ComPPI,IntAct
NDUFS7 NARS2 25348397 N/A physical interaction ComPPI
OTC NARS2 25348397 N/A physical interaction ComPPI
CLEC2D NARS2 25348397 N/A physical interaction ComPPI
HSPD1 NARS2 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CHRM3 NARS2 25348397 N/A physical interaction ComPPI
TMEM70 NARS2 25348397 N/A physical interaction ComPPI
TRMT61B NARS2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct

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