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GENE：NDOR1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NDOR1
FullNmae NADPH dependent diflavin oxidoreductase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29838
EnsembleID ENSG00000188566
Uniprot Q9UHB4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NDOR1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NDOR1 cuproptosis 36313717 Proteins carrying iron-sulfur clusters are essential for the basic metabolism of all organisms. Eukaryotic iron-sulfur cluster assembly includes direct mitochondrial iron-sulfur cluster (ISC) co-assembly pathway and cytosolic iron-sulfur cluster assembly (CIA) pathway that uses active sulfur as substrate, these pathways containing protein complex (composed of cysteine desulfurase, a scaffold protein, auxiliary ISD11 protein, acyl carrier protein, frataxin, and ferredoxin), the related genes (including NFS1, ISD11, ACP1, ISCU2, FXN, FDX2, FDXR) and proteins of cytokine induced apoptosis inhibitor 1 (CIAPIN1), novel diflavin oxidoreductase 1 (NDOR1), nucleotide binding protein 2 (NUBP2), nucleotide binding protein 1 (NUBP1), iron-only hydrogenase-like protein 1 (IOP1), and Cytosolic iron-Sulfur assembly component 1 (CIAO1) Proteins carrying iron-sulfur cluster
NDOR1 cuproptosis 36313717 The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in聽Table S1. Genes of iron-sulfur cluster related proteins

Go Annotation:

GeneSymbol Go id
NDOR1 GO:0003958,GO:0005515,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0009055,GO:0010181,GO:0010181,GO:0016226,GO:0016491,GO:0016653,GO:0016731,GO:0022900,GO:0045111,GO:0048471,GO:0050660,GO:0050661,GO:0070402,GO:0071949

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 NDOR1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF NDOR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NDOR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NDOR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NDOR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NDOR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000035CC3E NDOR1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000482389 NDOR1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000AF45F NDOR1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000061E50F NDOR1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD NDOR1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000553F51 NDOR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BD6DC NDOR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009EA8F NDOR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002E728C NDOR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000ECE9C NDOR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004E02F2 NDOR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A NDOR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE NDOR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001F373E NDOR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000027F5F3 NDOR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000045ED38 NDOR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B NDOR1 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DLG4 NDOR1 25361965 interaction type N/A PTMCode2
NDOR1 DLG4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ZNF774 NDOR1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TCHP NDOR1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CYCS NDOR1 10625700 25348397 27898060 N/A physical interaction,in vitro ComPPI,OmniPath
NLK NDOR1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DLG4 NDOR1 25348397 N/A two hybrid,in vitro,in vivo ComPPI
MEOX1 NDOR1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBQLN2 NDOR1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPS2 NDOR1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBQLN1 NDOR1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDOR1 RNASEH2A 25348397 N/A physical interaction ComPPI
NDOR1 SKIV2L 25348397 N/A physical interaction ComPPI
NDOR1 SETD3 25348397 N/A physical interaction ComPPI
NDOR1 TCF4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NDOR1 MTUS2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NDOR1 CIAPIN1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NDOR1 CCDC33 25348397 N/A physical interaction ComPPI
NDOR1 EFHC2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NDOR1 LNX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDOR1 NAB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDOR1 CENATAC 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDOR1 ZBTB42 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDOR1 TEPSIN 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDOR1 GAS8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDOR1 PSMB6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDOR1 REXO1L1P 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDOR1 HOXB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDOR1 KIAA0408 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDOR1 ZNF620 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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