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GENE：NDUFAB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NDUFAB1
FullNmae NADH:ubiquinone oxidoreductase subunit AB1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7694
EnsembleID ENSG00000004779
Uniprot O14561

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NDUFAB1 cuproptosis 36353226 Given that cuproptosis is triggered by lipoylated TCA cycle proteins, the protein lipoylation-related genes (GCSH,聽LIAS,聽LIPT1,聽LIPT2,聽NDUFAB1, and聽NNAT) among the different risk groups were analyzed. driver

Go Annotation:

GeneSymbol Go id
NDUFAB1 GO:0000035,GO:0000036,GO:0000036,GO:0005504,GO:0005509,GO:0005515,GO:0005654,GO:0005739,GO:0005739,GO:0005739,GO:0005743,GO:0005743,GO:0005747,GO:0005747,GO:0005747,GO:0005747,GO:0005747,GO:0005759,GO:0006120,GO:0006633,GO:0009060,GO:0009249,GO:0016226,GO:0031966,GO:0031966,GO:0032981,GO:0042776,GO:0044571,GO:0140978,GO:1990229

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NDUFAB1 hsa:4706 path:hsa00190 Oxidative phosphorylation - Homo sapiens (human)
NDUFAB1 hsa:4706 path:hsa01100 Metabolic pathways - Homo sapiens (human)
NDUFAB1 hsa:4706 path:hsa04714 Thermogenesis - Homo sapiens (human)
NDUFAB1 hsa:4706 path:hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human)
NDUFAB1 hsa:4706 path:hsa04932 Non-alcoholic fatty liver disease - Homo sapiens (human)
NDUFAB1 hsa:4706 path:hsa05010 Alzheimer disease - Homo sapiens (human)
NDUFAB1 hsa:4706 path:hsa05012 Parkinson disease - Homo sapiens (human)
NDUFAB1 hsa:4706 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
NDUFAB1 hsa:4706 path:hsa05016 Huntington disease - Homo sapiens (human)
NDUFAB1 hsa:4706 path:hsa05020 Prion disease - Homo sapiens (human)
NDUFAB1 hsa:4706 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
NDUFAB1 hsa:4706 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
NDUFAB1 hsa:4706 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MT-ND1 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND2 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND3 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND4 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND4L NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND5 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND6 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA1 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA12 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA13 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA2 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA3 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA4 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA5 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA6 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA7 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA8 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA9 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFAB1 NDUFA10 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFAB1 NDUFA11 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFAB1 NDUFB10 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFAB1 NDUFB11 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFAB1 NDUFB7 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFAB1 NDUFC2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFAB1 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB1 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB3 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB4 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB5 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB6 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB8 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB9 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS1 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS2 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS3 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS4 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS5 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS6 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS7 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS8 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV3 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
GZMA NDUFAB1 11413196 14499263 15607806 16106370 18485875 26192618 8432729 interaction type N/A ACSN
NDUFAF2 NDUFAB1 15526035 16200211 16218961 17344420 20025615 20816094 26192618 interaction type N/A ACSN
ACAD9 NDUFAB1 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26192618 26989860 interaction type N/A ACSN
ECSIT NDUFAB1 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26192618 26989860 interaction type N/A ACSN
NDUFAF1 NDUFAB1 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26192618 26989860 interaction type N/A ACSN
AIFM1 NDUFAB1 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389 26192618 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
ETS1 NDUFAB1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 NDUFAB1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 NDUFAB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NDUFAB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NDUFAB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NDUFAB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NDUFAB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 NDUFAB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NDUFAB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NDUFAB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F2 NDUFAB1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 NDUFAB1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
NDUFAB1 NDUFB4 25361965 interaction type N/A PTMCode2
NDUFB4 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFB7 25361965 interaction type N/A PTMCode2
NDUFB7 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFS7 25361965 interaction type N/A PTMCode2
NDUFS7 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFB3 25361965 interaction type N/A PTMCode2
NDUFB3 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFB2 25361965 interaction type N/A PTMCode2
NDUFB2 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFA2 25361965 interaction type N/A PTMCode2
NDUFA2 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFA10 25361965 interaction type N/A PTMCode2
NDUFA10 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFB5 25361965 interaction type N/A PTMCode2
NDUFB5 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFA9 25361965 interaction type N/A PTMCode2
NDUFA9 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFB10 25361965 interaction type N/A PTMCode2
NDUFB10 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFS6 25361965 interaction type N/A PTMCode2
NDUFS6 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 OXSM 25361965 interaction type N/A PTMCode2
OXSM NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFC2 25361965 interaction type N/A PTMCode2
NDUFC2 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFS4 25361965 interaction type N/A PTMCode2
NDUFS4 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFB8 25361965 interaction type N/A PTMCode2
NDUFB8 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFA7 25361965 interaction type N/A PTMCode2
NDUFA7 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFS8 25361965 interaction type N/A PTMCode2
NDUFS8 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 MDH2 25361965 interaction type N/A PTMCode2
MDH2 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFA12 25361965 interaction type N/A PTMCode2
NDUFA12 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFA6 25361965 interaction type N/A PTMCode2
NDUFA6 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFV3 25361965 interaction type N/A PTMCode2
NDUFV3 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 MT-ND1 25361965 interaction type N/A PTMCode2
MT-ND1 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 MT-ND5 25361965 interaction type N/A PTMCode2
MT-ND5 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 MT-ND4 25361965 interaction type N/A PTMCode2
MT-ND4 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFS2 25361965 interaction type N/A PTMCode2
NDUFS2 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFA1 25361965 interaction type N/A PTMCode2
NDUFA1 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFS5 25361965 interaction type N/A PTMCode2
NDUFS5 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFA8 25361965 interaction type N/A PTMCode2
NDUFA8 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFB6 25361965 interaction type N/A PTMCode2
NDUFB6 NDUFAB1 25361965 interaction type N/A PTMCode2
NDUFAB1 NDUFA3 25361965 interaction type N/A PTMCode2
NDUFA3 NDUFAB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
BEX5 NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FHL3 NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
OIP5 NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KCTD9 NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BOLA1 NDUFAB1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
ATPAF2 NDUFAB1 25348397 N/A physical interaction ComPPI
PSMC3 NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP1R16A NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CNTF NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MRPL23 NDUFAB1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NIT1 NDUFAB1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
TLX3 NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
POP5 NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HINFP NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LNX1 NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SMYD3 NDUFAB1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SPATA20 NDUFAB1 25348397 N/A physical interaction ComPPI
THAP1 NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FEM1A NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP5F1A NDUFAB1 25348397 N/A physical interaction ComPPI
NTAQ1 NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GLDC NDUFAB1 25348397 N/A physical interaction ComPPI
NDUFS6 NDUFAB1 25348397 N/A physical interaction ComPPI
MGST3 NDUFAB1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ACP6 NDUFAB1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NDUFA6 NDUFAB1 12611891 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
VAC14 NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ETFA NDUFAB1 25348397 N/A physical interaction ComPPI
ETFB NDUFAB1 25348397 N/A physical interaction ComPPI
SDHB NDUFAB1 25348397 N/A physical interaction ComPPI
BBC3 NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDUFA9 NDUFAB1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLIRP NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MCCC2 NDUFAB1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NDUFS3 NDUFAB1 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPL11 NDUFAB1 25348397 N/A physical interaction ComPPI
MRPL46 NDUFAB1 25348397 N/A physical interaction ComPPI
NFS1 NDUFAB1 25348397 N/A physical interaction ComPPI
CCDC24 NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MIX23 NDUFAB1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
LYRM7 NDUFAB1 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
OXSM NDUFAB1 25348397 N/A physical interaction ComPPI
NT5C3A NDUFAB1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RBM18 NDUFAB1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NDUFAB1 SDHAF3 25348397 N/A physical interaction ComPPI
NDUFAB1 LYRM4 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFAB1 ETFRF1 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFAB1 NDUFA11 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFAB1 LYRM1 25348397 N/A physical interaction ComPPI
NDUFAB1 FMC1 25348397 N/A physical interaction ComPPI
NDUFAB1 NDUFAF5 25348397 N/A physical interaction ComPPI
NDUFAB1 ZNF19 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDUFAB1 LINC02875 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDUFAB1 MORN3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDUFAB1 SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
LYRM2 NDUFAB1 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
METTL3 NDUFAB1 24234451 29507755 association anti tag coimmunoprecipitation IntAct

Visualization










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