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GENE：NDUFB2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NDUFB2
FullNmae NADH:ubiquinone oxidoreductase subunit B2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7697
EnsembleID ENSG00000090266
Uniprot O95178

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NDUFB2 cuproptosis 36118866 FeS Cluster cuproptosis gene
NDUFB2 cuproptosis 36685880 A total of 43 CRGs were manually identified and used to investigate the effects of cuproptosis in HNSC in current study. cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
NDUFB2 GO:0005743,GO:0005743,GO:0005747,GO:0005747,GO:0005747,GO:0005747,GO:0006120,GO:0008137,GO:0009060,GO:0032981,GO:0032981,GO:0042776

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NDUFB2 hsa:4708 path:hsa00190 Oxidative phosphorylation - Homo sapiens (human)
NDUFB2 hsa:4708 path:hsa01100 Metabolic pathways - Homo sapiens (human)
NDUFB2 hsa:4708 path:hsa04714 Thermogenesis - Homo sapiens (human)
NDUFB2 hsa:4708 path:hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human)
NDUFB2 hsa:4708 path:hsa04932 Non-alcoholic fatty liver disease - Homo sapiens (human)
NDUFB2 hsa:4708 path:hsa05010 Alzheimer disease - Homo sapiens (human)
NDUFB2 hsa:4708 path:hsa05012 Parkinson disease - Homo sapiens (human)
NDUFB2 hsa:4708 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
NDUFB2 hsa:4708 path:hsa05016 Huntington disease - Homo sapiens (human)
NDUFB2 hsa:4708 path:hsa05020 Prion disease - Homo sapiens (human)
NDUFB2 hsa:4708 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
NDUFB2 hsa:4708 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
NDUFB2 hsa:4708 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MT-ND1 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND2 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND3 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND4 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND4L NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND5 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND6 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA1 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA7 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFA10 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFA11 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFA12 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFA13 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFA2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFA3 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFA4 12601012 12667446 15186778 15526035 15807660 16200211 16218961 16246152 17344420 18485875 19131594 20025615 20816094 23850759 26192618 interaction type N/A ACSN
NDUFB2 NDUFA5 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFA6 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFA8 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFA9 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFB10 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFB11 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFB3 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFB7 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFB8 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFC2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFS3 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFS4 12601012 12667446 15186778 15526035 15807660 16200211 16218961 16246152 17344420 18485875 19131594 20025615 20816094 23850759 26192618 interaction type N/A ACSN
NDUFB2 NDUFS5 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFS6 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFS7 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFV3 12601012 12667446 15186778 15526035 15807660 16200211 16218961 16246152 17344420 18485875 19131594 20025615 20816094 23850759 26192618 interaction type N/A ACSN
NDUFB4 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB5 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB6 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB9 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS1 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS2 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS8 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
GZMA NDUFB2 11413196 14499263 15607806 16106370 18485875 26192618 8432729 interaction type N/A ACSN
NDUFAF2 NDUFB2 15526035 16200211 16218961 17344420 20025615 20816094 26192618 interaction type N/A ACSN
ACAD9 NDUFB2 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26192618 26989860 interaction type N/A ACSN
ECSIT NDUFB2 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26192618 26989860 interaction type N/A ACSN
NDUFAF1 NDUFB2 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26192618 26989860 interaction type N/A ACSN
AIFM1 NDUFB2 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389 26192618 interaction type N/A ACSN
NDUFB2 EIF2S1 26192618 association N/A ACSN
NDUFB2 EIF2S2 26192618 association N/A ACSN
NDUFB2 EIF2S3 26192618 association N/A ACSN

Source Target Pmid Interactiontype Methods Database
E2F1 NDUFB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NDUFB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 NDUFB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NDUFB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 NDUFB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000016914 NDUFB2 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NDUFAB1 NDUFB2 25361965 interaction type N/A PTMCode2
NDUFB2 NDUFAB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PFKM NDUFB2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NDUFA6 NDUFB2 12611891 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B8167 NDUFB2 27087310 direct interaction,inhibition N/A NPInter

Visualization










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