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GENE：NDUFC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NDUFC1
FullNmae NADH:ubiquinone oxidoreductase subunit C1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7705
EnsembleID ENSG00000109390
Uniprot O43677

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NDUFC1 cuproptosis 36118866 FeS Cluster cuproptosis gene
NDUFC1 cuproptosis 36685880 A total of 43 CRGs were manually identified and used to investigate the effects of cuproptosis in HNSC in current study. cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
NDUFC1 GO:0005743,GO:0005743,GO:0005747,GO:0005747,GO:0005747,GO:0005747,GO:0006120,GO:0008137,GO:0009060,GO:0032981,GO:0042776

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NDUFC1 hsa:4717 path:hsa00190 Oxidative phosphorylation - Homo sapiens (human)
NDUFC1 hsa:4717 path:hsa01100 Metabolic pathways - Homo sapiens (human)
NDUFC1 hsa:4717 path:hsa04714 Thermogenesis - Homo sapiens (human)
NDUFC1 hsa:4717 path:hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human)
NDUFC1 hsa:4717 path:hsa04932 Non-alcoholic fatty liver disease - Homo sapiens (human)
NDUFC1 hsa:4717 path:hsa05010 Alzheimer disease - Homo sapiens (human)
NDUFC1 hsa:4717 path:hsa05012 Parkinson disease - Homo sapiens (human)
NDUFC1 hsa:4717 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
NDUFC1 hsa:4717 path:hsa05016 Huntington disease - Homo sapiens (human)
NDUFC1 hsa:4717 path:hsa05020 Prion disease - Homo sapiens (human)
NDUFC1 hsa:4717 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
NDUFC1 hsa:4717 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
NDUFC1 hsa:4717 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MT-ND1 NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND2 NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND3 NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND4 NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND4L NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND5 NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND6 NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA1 NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA7 NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB4 NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB5 NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB6 NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB9 NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFA10 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFA11 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFA12 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFA13 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFA2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFA3 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFA4 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFA5 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFA6 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFA8 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFA9 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFB10 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFB11 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFB3 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFB7 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFB8 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFC2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFS3 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFS4 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFS5 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFS6 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFS7 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFV3 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS1 NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS2 NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS8 NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 EIF2S3 16246152 23850759 26192618 association N/A ACSN
GZMA NDUFC1 11413196 14499263 15607806 16106370 18485875 26192618 8432729 interaction type N/A ACSN
NDUFAF2 NDUFC1 15526035 16200211 16218961 17344420 20025615 20816094 26192618 interaction type N/A ACSN
ACAD9 NDUFC1 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26192618 26989860 interaction type N/A ACSN
ECSIT NDUFC1 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26192618 26989860 interaction type N/A ACSN
NDUFAF1 NDUFC1 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26192618 26989860 interaction type N/A ACSN
AIFM1 NDUFC1 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389 26192618 interaction type N/A ACSN
NDUFC1 EIF2S1 26192618 association N/A ACSN
NDUFC1 EIF2S2 26192618 association N/A ACSN

Source Target Pmid Interactiontype Methods Database
AR NDUFC1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 NDUFC1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 NDUFC1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A NDUFC1 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SMARCA4 NDUFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NDUFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NDUFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 NDUFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 NDUFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NDUFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 NDUFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 NDUFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR NDUFC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NDUFC1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00009B8B73 NDUFC1 27087310 direct interaction,inhibition N/A NPInter

Visualization










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