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GENE：NDUFV1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NDUFV1
FullNmae NADH:ubiquinone oxidoreductase core subunit V1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7716
EnsembleID ENSG00000167792
Uniprot P49821

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NDUFV1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
NDUFV1 GO:0005515,GO:0005739,GO:0005743,GO:0005743,GO:0005743,GO:0005747,GO:0005747,GO:0005747,GO:0005747,GO:0005747,GO:0005829,GO:0006120,GO:0006120,GO:0006120,GO:0008137,GO:0009060,GO:0010181,GO:0042775,GO:0042776,GO:0046872,GO:0051287,GO:0051539

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NDUFV1 hsa:4723 path:hsa00190 Oxidative phosphorylation - Homo sapiens (human)
NDUFV1 hsa:4723 path:hsa01100 Metabolic pathways - Homo sapiens (human)
NDUFV1 hsa:4723 path:hsa04714 Thermogenesis - Homo sapiens (human)
NDUFV1 hsa:4723 path:hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human)
NDUFV1 hsa:4723 path:hsa04932 Non-alcoholic fatty liver disease - Homo sapiens (human)
NDUFV1 hsa:4723 path:hsa05010 Alzheimer disease - Homo sapiens (human)
NDUFV1 hsa:4723 path:hsa05012 Parkinson disease - Homo sapiens (human)
NDUFV1 hsa:4723 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
NDUFV1 hsa:4723 path:hsa05016 Huntington disease - Homo sapiens (human)
NDUFV1 hsa:4723 path:hsa05020 Prion disease - Homo sapiens (human)
NDUFV1 hsa:4723 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
NDUFV1 hsa:4723 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
NDUFV1 hsa:4723 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MT-ND1 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND2 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND3 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND4 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND4L NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND5 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND6 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA1 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA12 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA13 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA2 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA3 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA4 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA5 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA6 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA7 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA8 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA9 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFAB1 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB1 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB2 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB3 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB4 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB5 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB6 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB7 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB8 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB9 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFC1 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS1 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS2 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS3 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS4 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS5 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS6 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS7 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS8 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV1 NDUFA10 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV1 NDUFA11 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV1 NDUFB10 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV1 NDUFB11 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV1 NDUFC2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV3 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
GZMA NDUFV1 11413196 14499263 15607806 16106370 18485875 26192618 8432729 interaction type N/A ACSN
NDUFAF2 NDUFV1 15526035 16200211 16218961 17344420 20025615 20816094 26192618 interaction type N/A ACSN
ACAD9 NDUFV1 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26192618 26989860 interaction type N/A ACSN
ECSIT NDUFV1 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26192618 26989860 interaction type N/A ACSN
NDUFAF1 NDUFV1 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26192618 26989860 interaction type N/A ACSN
AIFM1 NDUFV1 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389 26192618 interaction type N/A ACSN
ADRB2 NDUFV1 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 NDUFV1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 NDUFV1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 NDUFV1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
E2F4 NDUFV1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 NDUFV1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 NDUFV1 17786189 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 NDUFV1 17786189 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NDUFV1 N/A trascriptional regulation,stimulation inferred by curator TFlink
MYC NDUFV1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005651EE NDUFV1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PSMD7 NDUFV1 25348397 N/A physical interaction ComPPI
COX5A NDUFV1 25348397 N/A physical interaction ComPPI
TIMMDC1 NDUFV1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFAF4 NDUFV1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
PAK5 NDUFV1 25348397 N/A physical interaction ComPPI
COPS5 NDUFV1 25348397 N/A physical interaction ComPPI
VAPA NDUFV1 25348397 N/A physical interaction ComPPI
SLC9A3R2 NDUFV1 25348397 N/A physical interaction ComPPI
ABCD3 NDUFV1 25348397 N/A physical interaction ComPPI
NIT1 NDUFV1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
STXBP1 NDUFV1 25348397 N/A physical interaction ComPPI
NPHP1 NDUFV1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
VDAC1 NDUFV1 24234451 25348397 29128334 colocalization fluorescence microscopy ComPPI,IntAct
EWSR1 NDUFV1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PDHA1 NDUFV1 25348397 N/A physical interaction ComPPI
MT-ND1 NDUFV1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RRM1 NDUFV1 25348397 N/A physical interaction ComPPI
VDAC2 NDUFV1 25348397 N/A physical interaction ComPPI
TPI1 NDUFV1 25348397 N/A physical interaction ComPPI
ATP1A1 NDUFV1 25348397 N/A physical interaction ComPPI
ATP1B1 NDUFV1 25348397 N/A physical interaction ComPPI
ANXA11 NDUFV1 25348397 N/A physical interaction ComPPI
ADRB2 NDUFV1 25348397 N/A physical interaction ComPPI
HTT NDUFV1 17500595 24234451 25348397 association pull down ComPPI,IntAct
PHB2 NDUFV1 25348397 N/A physical interaction ComPPI
PALLD NDUFV1 25348397 N/A physical interaction ComPPI
HTRA2 NDUFV1 25348397 N/A physical interaction ComPPI
PDK1 NDUFV1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
DNAJB11 NDUFV1 25348397 N/A physical interaction ComPPI
NOTCH2 NDUFV1 25348397 N/A physical interaction ComPPI
HNRNPR NDUFV1 25348397 N/A physical interaction ComPPI
TRIM25 NDUFV1 25348397 N/A physical interaction ComPPI
STMN1 NDUFV1 25348397 N/A physical interaction ComPPI
NDUFS7 NDUFV1 25348397 N/A physical interaction ComPPI
EEF2 NDUFV1 25348397 N/A physical interaction ComPPI
AURKAIP1 NDUFV1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
VPS29 NDUFV1 25348397 N/A physical interaction ComPPI
NDUFA13 NDUFV1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ERGIC1 NDUFV1 25348397 N/A physical interaction ComPPI
TOMM40 NDUFV1 25348397 N/A physical interaction ComPPI
HSPD1 NDUFV1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TCOF1 NDUFV1 25348397 N/A physical interaction ComPPI
ILF3 NDUFV1 25348397 N/A physical interaction ComPPI
NDUFV2 NDUFV1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POR NDUFV1 25348397 N/A physical interaction ComPPI
CPT1A NDUFV1 25348397 N/A physical interaction ComPPI
PNP NDUFV1 25348397 N/A physical interaction ComPPI
ATP6V0D1 NDUFV1 25348397 N/A physical interaction ComPPI
NDUFV1 MRPL58 20186120 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV1 NDUFS8 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV1 NDUFS3 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV1 NDUFS2 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV1 NDUFS1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV1 NDUFA9 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV1 NDUFB6 25348397 N/A physical interaction ComPPI
NDUFV1 NDUFB10 25348397 N/A physical interaction ComPPI
NDUFV1 PEDS1 25348397 N/A physical interaction ComPPI
NDUFV1 TIMM9 25348397 N/A physical interaction ComPPI
NDUFV1 MPST 25348397 N/A physical interaction ComPPI
NDUFV1 TOR1AIP1 25348397 N/A physical interaction ComPPI
NDUFV1 HSPA1L 25348397 N/A physical interaction ComPPI
NDUFV1 SDHA 25348397 N/A physical interaction ComPPI
NDUFV1 RNASET2 25348397 N/A physical interaction ComPPI
NDUFV1 NDUFA8 25348397 N/A physical interaction ComPPI
NDUFV1 MRPL45 25348397 N/A physical interaction ComPPI
NDUFV1 ATP5PB 25348397 N/A physical interaction ComPPI
NDUFV1 FH 25348397 N/A physical interaction ComPPI
NDUFV1 MTCH1 25348397 N/A physical interaction ComPPI
NDUFV1 NDUFA10 25348397 N/A physical interaction ComPPI
NDUFV1 NDUFA2 19688755 24234451 24344204 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,blue native page ComPPI,IntAct
NDUFV1 NDUFB8 25348397 N/A physical interaction ComPPI
NDUFV1 NDUFS4 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV1 UQCRB 25348397 N/A physical interaction ComPPI
NDUFV1 SDHB 25348397 N/A physical interaction ComPPI
NDUFV1 UQCRFS1 25348397 N/A physical interaction ComPPI
NDUFV1 NDUFA12 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV1 NDUFS5 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV1 NDUFA11 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV1 NDUFS6 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV1 OXCT1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV1 NDUFV3 24234451 24344204 25348397 30021884 association,physical association anti tag coimmunoprecipitation,cross-linking study,physical interaction ComPPI,IntAct
NDUFV1 MT-ND5 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV1 NDUFB4 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV1 GOLT1B 25348397 N/A physical interaction ComPPI
NDUFV1 FOXQ1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NDUFV1 NDUFA4 25348397 N/A physical interaction ComPPI
NDUFV1 NMES1 25348397 N/A physical interaction ComPPI
NDUFV1 OCIAD1 25348397 N/A physical interaction ComPPI
NDUFV1 COX6B1 25348397 N/A physical interaction ComPPI
NDUFV1 FMC1 25348397 N/A physical interaction ComPPI
NDUFV1 MTRES1 25348397 N/A physical interaction ComPPI
NDUFV1 COA3 25348397 N/A physical interaction ComPPI
NDUFV1 NDUFB11 25348397 N/A physical interaction ComPPI
NDUFV1 SIRT4 24234451 25348397 25525879 association anti tag coimmunoprecipitation ComPPI,IntAct
NDUFV1 NDUFA6 12611891 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
NDUFV1 AIFM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NDUFV1 COX14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NDUFV1 SFXN1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NDUFV1 DHRS4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NDUFV1 NDUFAF8 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NDUFV1 COQ3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NDUFV1 MIX23 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NDUFV1 OPA3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NDUFV1 SDHAF4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
PAICS NDUFV1 25348397 N/A physical interaction ComPPI
MGST3 NDUFV1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRMT61B NDUFV1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HSCB NDUFV1 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
NDUFV1 DRD2 24234451 28298427 physical association ubiquitin reconstruction IntAct

Visualization










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