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GENE：NDUFV2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NDUFV2
FullNmae NADH:ubiquinone oxidoreductase core subunit V2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7717
EnsembleID ENSG00000178127
Uniprot P19404

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NDUFV2 cuproptosis 36118866 FeS Cluster cuproptosis gene
NDUFV2 cuproptosis 36685880 A total of 43 CRGs were manually identified and used to investigate the effects of cuproptosis in HNSC in current study. cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
NDUFV2 GO:0003954,GO:0005515,GO:0005739,GO:0005743,GO:0005743,GO:0005747,GO:0005747,GO:0005747,GO:0005747,GO:0005747,GO:0006120,GO:0006120,GO:0006120,GO:0007399,GO:0008137,GO:0008137,GO:0009055,GO:0009060,GO:0042776,GO:0046872,GO:0048738,GO:0051537

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NDUFV2 hsa:4729 path:hsa00190 Oxidative phosphorylation - Homo sapiens (human)
NDUFV2 hsa:4729 path:hsa01100 Metabolic pathways - Homo sapiens (human)
NDUFV2 hsa:4729 path:hsa04714 Thermogenesis - Homo sapiens (human)
NDUFV2 hsa:4729 path:hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human)
NDUFV2 hsa:4729 path:hsa04932 Non-alcoholic fatty liver disease - Homo sapiens (human)
NDUFV2 hsa:4729 path:hsa05010 Alzheimer disease - Homo sapiens (human)
NDUFV2 hsa:4729 path:hsa05012 Parkinson disease - Homo sapiens (human)
NDUFV2 hsa:4729 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
NDUFV2 hsa:4729 path:hsa05016 Huntington disease - Homo sapiens (human)
NDUFV2 hsa:4729 path:hsa05020 Prion disease - Homo sapiens (human)
NDUFV2 hsa:4729 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
NDUFV2 hsa:4729 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
NDUFV2 hsa:4729 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MT-ND1 NDUFV2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND2 NDUFV2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND3 NDUFV2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND4 NDUFV2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND4L NDUFV2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND5 NDUFV2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
MT-ND6 NDUFV2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA1 NDUFV2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFA7 NDUFV2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB4 NDUFV2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB5 NDUFV2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB6 NDUFV2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFB9 NDUFV2 12847084 15186778 15526035 15807660 16186509 16200211 16218961 17344420 18199748 18360008 18485875 19131594 19509052 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS1 NDUFV2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS2 NDUFV2 12847084 15186778 15526035 15807660 16186509 16200211 16218961 17344420 18485875 19131594 19509052 20025615 20816094 26192618 interaction type N/A ACSN
NDUFS8 NDUFV2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFA10 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFA11 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFA12 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFA13 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFA2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFA3 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFA4 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFA5 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFA6 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFA8 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFA9 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFAB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFB1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFB10 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFB11 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFB2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFB3 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFB7 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFB8 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFC1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFC2 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFS3 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFS4 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFS5 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFS6 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFS7 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFV1 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
NDUFV2 NDUFV3 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094 26192618 interaction type N/A ACSN
GZMA NDUFV2 11413196 14499263 15607806 16106370 18485875 26192618 8432729 interaction type N/A ACSN
NDUFAF2 NDUFV2 15526035 16200211 16218961 17344420 20025615 20816094 26192618 interaction type N/A ACSN
ACAD9 NDUFV2 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26192618 26989860 interaction type N/A ACSN
ECSIT NDUFV2 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26192618 26989860 interaction type N/A ACSN
NDUFAF1 NDUFV2 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26192618 26989860 interaction type N/A ACSN
AIFM1 NDUFV2 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389 26192618 interaction type N/A ACSN
SEL1L NDUFV2 12847084 15186778 15526035 15807660 16186509 16200211 16218961 17344420 18199748 18360008 18485875 19131594 19509052 20025615 20816094 26192618 interaction type N/A ACSN
SYVN1 NDUFV2 12847084 15186778 15526035 15807660 16186509 16200211 16218961 17344420 18199748 18360008 18485875 19131594 19509052 20025615 20816094 26192618 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
AR NDUFV2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 NDUFV2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 NDUFV2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 NDUFV2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 NDUFV2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 NDUFV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NDUFV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NDUFV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NDUFV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NDUFV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NDUFV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NDUFV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 NDUFV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NDUFV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A NDUFV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NDUFV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NDUFV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 NDUFV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 NDUFV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 NDUFV2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 NDUFV2 17786189 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 NDUFV2 17786189 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
SRC NDUFV2 22135298 phosphorylation N/A PhosphoSite
NDUFA9 NDUFV2 25361965 interaction type N/A PTMCode2
NDUFV2 NDUFA9 25361965 interaction type N/A PTMCode2
NDUFA2 NDUFV2 25361965 interaction type N/A PTMCode2
NDUFV2 NDUFA2 25361965 interaction type N/A PTMCode2
NDUFS7 NDUFV2 25361965 interaction type N/A PTMCode2
NDUFV2 NDUFS7 25361965 interaction type N/A PTMCode2
NDUFS8 NDUFV2 25361965 interaction type N/A PTMCode2
NDUFV2 NDUFS8 25361965 interaction type N/A PTMCode2
NDUFV2 NDUFS2 25361965 interaction type N/A PTMCode2
NDUFS2 NDUFV2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
FOXB1 NDUFV2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NDUFAF4 NDUFV2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
FOXG1 NDUFV2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
JUN NDUFV2 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
VAPA NDUFV2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB7A NDUFV2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NIT1 NDUFV2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
VDAC1 NDUFV2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MT-ND1 NDUFV2 25348397 N/A physical interaction ComPPI
TPI1 NDUFV2 25348397 N/A physical interaction ComPPI
SYNCRIP NDUFV2 25348397 N/A physical interaction ComPPI
RASSF1 NDUFV2 25348397 N/A physical interaction ComPPI
UQCRC1 NDUFV2 25348397 N/A physical interaction ComPPI
CRMP1 NDUFV2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SUCLG2 NDUFV2 25348397 N/A physical interaction ComPPI
PDK1 NDUFV2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SVIL NDUFV2 25348397 N/A physical interaction ComPPI
NOTCH2 NDUFV2 25348397 N/A physical interaction ComPPI
NPC2 NDUFV2 25348397 N/A physical interaction ComPPI
SEPTIN9 NDUFV2 25348397 N/A physical interaction ComPPI
NDUFS7 NDUFV2 25348397 N/A physical interaction ComPPI
AURKAIP1 NDUFV2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NDUFA13 NDUFV2 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPD1 NDUFV2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CCNC NDUFV2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KAT5 NDUFV2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NDUFV2 SP110 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NDUFV2 NDUFS2 15250827 24234451 24344204 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV2 NDUFS3 15250827 24234451 24344204 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV2 NDUFS8 25348397 N/A physical interaction ComPPI
NDUFV2 NDUFS1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV2 NDUFV1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV2 NDUFB4 25348397 N/A physical interaction ComPPI
NDUFV2 NDUFV3 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV2 NDUFA10 25348397 N/A physical interaction ComPPI
NDUFV2 NPTN 25348397 N/A physical interaction ComPPI
NDUFV2 SURF1 25348397 N/A physical interaction ComPPI
NDUFV2 PITRM1 25348397 N/A physical interaction ComPPI
NDUFV2 TMED9 25348397 N/A physical interaction ComPPI
NDUFV2 SLC25A3 25348397 N/A physical interaction ComPPI
NDUFV2 TJP1 25348397 N/A physical interaction ComPPI
NDUFV2 SDHB 25348397 N/A physical interaction ComPPI
NDUFV2 SDHA 25348397 N/A physical interaction ComPPI
NDUFV2 PCYOX1 25348397 N/A physical interaction ComPPI
NDUFV2 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
NDUFV2 NDUFA8 25348397 N/A physical interaction ComPPI
NDUFV2 MT-CO2 25348397 N/A physical interaction ComPPI
NDUFV2 NDUFA6 12611891 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV2 NDUFA2 19688755 24234451 25348397 physical association physical interaction,blue native page ComPPI,IntAct
NDUFV2 NDUFB10 25348397 N/A physical interaction ComPPI
NDUFV2 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NDUFV2 NDUFA12 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV2 NDUFS4 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV2 NDUFS5 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV2 NDUFA9 15250827 24234451 24344204 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,blue native page ComPPI,IntAct
NDUFV2 NDUFA11 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV2 NDUFS6 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV2 MT-ND5 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV2 GOLT1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV2 MMGT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFV2 NDUFA4 25348397 N/A physical interaction ComPPI
NDUFV2 NMES1 25348397 N/A physical interaction ComPPI
NDUFV2 NDUFB11 25348397 N/A physical interaction ComPPI
NDUFV2 FAM114A2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDUFV2 GOLM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDUFV2 AIFM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NDUFV2 SFXN1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NDUFV2 NDUFAF8 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
MGST3 NDUFV2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRMT61B NDUFV2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HSCB NDUFV2 24234451 25348397 28380382 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
SRC NDUFV2 22823520 27898060 N/A N/A OmniPath

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