Gene Information gene info

  1. Home

GENE：NUBP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NUBP2
FullNmae NUBP iron-sulfur cluster assembly factor 2, cytosolic
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8042
EnsembleID ENSG00000095906
Uniprot Q9Y5Y2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NUBP2 cuproptosis 36313717 Proteins carrying iron-sulfur clusters are essential for the basic metabolism of all organisms. Eukaryotic iron-sulfur cluster assembly includes direct mitochondrial iron-sulfur cluster (ISC) co-assembly pathway and cytosolic iron-sulfur cluster assembly (CIA) pathway that uses active sulfur as substrate, these pathways containing protein complex (composed of cysteine desulfurase, a scaffold protein, auxiliary ISD11 protein, acyl carrier protein, frataxin, and ferredoxin), the related genes (including NFS1, ISD11, ACP1, ISCU2, FXN, FDX2, FDXR) and proteins of cytokine induced apoptosis inhibitor 1 (CIAPIN1), novel diflavin oxidoreductase 1 (NDOR1), nucleotide binding protein 2 (NUBP2), nucleotide binding protein 1 (NUBP1), iron-only hydrogenase-like protein 1 (IOP1), and Cytosolic iron-Sulfur assembly component 1 (CIAO1) Proteins carrying iron-sulfur cluster
NUBP2 cuproptosis 36313717 The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in聽Table S1. Genes of iron-sulfur cluster related proteins

Go Annotation:

GeneSymbol Go id
NUBP2 GO:0000166,GO:0005515,GO:0005524,GO:0005634,GO:0005814,GO:0005829,GO:0005929,GO:0016226,GO:0030030,GO:0031616,GO:0046872,GO:0051536,GO:0051539,GO:0140663

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 NUBP2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF NUBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NUBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NUBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 NUBP2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 NUBP2 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase

Source Target Pmid Interactiontype Methods Database
MAD2L2 NUBP2 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
CIAO1 NUBP2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
BAG3 NUBP2 25348397 N/A physical interaction ComPPI
KRTAP10-7 NUBP2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NUBP2 IGBP1 25348397 N/A physical interaction ComPPI
NUBP2 PEX19 25348397 N/A physical interaction ComPPI
NUBP2 RBBP6 25348397 N/A physical interaction ComPPI
NUBP2 RHOA 25348397 N/A physical interaction ComPPI
NUBP2 UBXN7 25348397 N/A physical interaction ComPPI
NUBP2 PAIP1 25348397 N/A physical interaction ComPPI
NUBP2 PPP2CA 25348397 N/A physical interaction ComPPI
NUBP2 PTMA 25348397 N/A physical interaction ComPPI
NUBP2 SRSF2 25348397 N/A physical interaction ComPPI
NUBP2 STAT6 25348397 N/A physical interaction ComPPI
NUBP2 STUB1 25348397 N/A physical interaction ComPPI
NUBP2 TARDBP 25348397 N/A physical interaction ComPPI
NUBP2 NUDC 25348397 N/A physical interaction ComPPI
NUBP2 PPP1R14B 25348397 N/A physical interaction ComPPI
NUBP2 PSMD6 25348397 N/A physical interaction ComPPI
NUBP2 RAD23B 25348397 N/A physical interaction ComPPI
NUBP2 YAP1 25348397 N/A physical interaction ComPPI
NUBP2 PABPC4 25348397 N/A physical interaction ComPPI
NUBP2 PSMD4 25348397 N/A physical interaction ComPPI
NUBP2 PSME1 25348397 N/A physical interaction ComPPI
NUBP2 PTMS 25348397 N/A physical interaction ComPPI
NUBP2 S100A9 25348397 N/A physical interaction ComPPI
NUBP2 SEC24A 25348397 N/A physical interaction ComPPI
NUBP2 USP9X 25348397 N/A physical interaction ComPPI
NUBP2 ZRANB2 25348397 N/A physical interaction ComPPI
NUBP2 H2AZ2 25348397 N/A physical interaction ComPPI
NUBP2 TNS2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NUBP2 KRTAP10-3 25348397 N/A physical interaction ComPPI
NUBP2 EGFR 25348397 N/A physical interaction ComPPI
NUBP2 CDK5 25348397 N/A physical interaction ComPPI
NUBP2 DCTN1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NUBP2 TRIM25 25348397 N/A physical interaction ComPPI
NUBP2 PTP4A3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NUBP2 MDFI 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NUBP2 INCA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NUBP2 TGM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2R2 NUBP2 25348397 N/A physical interaction ComPPI
PTGER4 NUBP2 24234451 28298427 physical association ubiquitin reconstruction IntAct

Visualization










  Return