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GENE：NUP133

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NUP133
FullNmae nucleoporin 133
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18016
EnsembleID ENSG00000069248
Uniprot Q8WUM0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NUP133 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NUP133 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
NUP133 GO:0000776,GO:0000972,GO:0005515,GO:0005635,GO:0005635,GO:0005643,GO:0005643,GO:0005829,GO:0006406,GO:0006606,GO:0006913,GO:0006999,GO:0016020,GO:0016973,GO:0017056,GO:0017056,GO:0021915,GO:0022008,GO:0031080,GO:0031080,GO:0031080,GO:0031965,GO:0048339,GO:0061053,GO:0072006

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NUP133 hsa:55746 path:hsa03013 Nucleocytoplasmic transport - Homo sapiens (human)
NUP133 hsa:55746 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 NUP133 19374776 23180781 physical association anti tag coimmunoprecipitation InnateDB
EED NUP133 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR NUP133 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 NUP133 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 NUP133 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 NUP133 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 NUP133 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 NUP133 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 NUP133 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NUP133 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NUP133 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NUP133 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NUP133 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 NUP133 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000FC8EB NUP133 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000032FC1A NUP133 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000022AAA NUP133 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 NUP133 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000272039 NUP133 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 NUP133 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F NUP133 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK2 NUP133 22135298 phosphorylation N/A PhosphoSite
NUP37 NUP133 25361965 interaction type N/A PTMCode2
NUP133 NUP37 25361965 interaction type N/A PTMCode2
NUP107 NUP133 25361965 interaction type N/A PTMCode2
NUP133 NUP107 25361965 interaction type N/A PTMCode2
NUP133 NUP98 25361965 interaction type N/A PTMCode2
NUP98 NUP133 25361965 interaction type N/A PTMCode2
NUP133 NUP43 25361965 interaction type N/A PTMCode2
NUP43 NUP133 25361965 interaction type N/A PTMCode2
NUP133 CENPF 25361965 interaction type N/A PTMCode2
CENPF NUP133 25361965 interaction type N/A PTMCode2
NUP133 NUP160 25361965 interaction type N/A PTMCode2
NUP160 NUP133 25361965 interaction type N/A PTMCode2
NUP133 SEH1L 25361965 interaction type N/A PTMCode2
SEH1L NUP133 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
VIM NUP133 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLE4 NUP133 25348397 N/A physical interaction ComPPI
LMNA NUP133 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
KEAP1 NUP133 25348397 N/A physical interaction ComPPI
CPSF7 NUP133 25348397 N/A physical interaction ComPPI
NONO NUP133 25348397 N/A physical interaction ComPPI
FLNC NUP133 25348397 N/A physical interaction ComPPI
KPNB1 NUP133 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUP85 NUP133 24234451 24315095 25348397 27194810 physical association affinity chromatography technology,bimolecular fluorescence complementation ComPPI,IntAct
UBC NUP133 25348397 N/A physical interaction ComPPI
NTRK1 NUP133 25348397 N/A physical interaction ComPPI
CANX NUP133 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PSAP NUP133 25348397 N/A physical interaction ComPPI
MYC NUP133 17314511 17353931 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
NUP98 NUP133 11564755 14525934 24234451 25348397 association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
TMPO NUP133 25348397 N/A physical interaction ComPPI
ACTR1A NUP133 25348397 N/A physical interaction ComPPI
RAF1 NUP133 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TCAP NUP133 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
RNF2 NUP133 25348397 N/A physical interaction ComPPI
UBE2A NUP133 25348397 N/A physical interaction ComPPI
WWOX NUP133 25348397 N/A physical interaction ComPPI
EED NUP133 25348397 N/A physical interaction ComPPI
DDX3X NUP133 25348397 N/A physical interaction ComPPI
HDAC11 NUP133 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUP153 NUP133 17363900 24234451 25348397 26496610 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RANBP2 NUP133 25348397 N/A physical interaction ComPPI
ZMYM2 NUP133 25348397 N/A physical interaction ComPPI
DYNC1H1 NUP133 25348397 N/A physical interaction ComPPI
SEC13 NUP133 25348397 N/A physical interaction ComPPI
CENPF NUP133 14525934 17363900 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
DDX1 NUP133 25348397 N/A physical interaction ComPPI
NUP50 NUP133 25348397 N/A physical interaction ComPPI
DDB1 NUP133 25348397 N/A physical interaction ComPPI
NUP54 NUP133 24234451 25348397 27194810 physical association two hybrid,two hybrid array ComPPI,IntAct
NUP133 NUP107 11564755 14525934 15146057 17360435 17363900 19674973 20676042 22939629 24234451 24927568 25348397 26344197 26496610 27194810 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,bimolecular fluorescence complementation,inference by socio-affinity scoring ComPPI,HPRD,IntAct,OmniPath
NUP133 SEH1L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUP133 NUP43 25348397 N/A physical interaction ComPPI
NUP133 NUP37 25348397 N/A physical interaction ComPPI
NUP133 SIRT7 25348397 N/A physical interaction ComPPI
NUP133 DBN1 25348397 N/A physical interaction ComPPI
NUP133 FBXO6 25348397 N/A physical interaction ComPPI
NUP133 OBSL1 25348397 N/A physical interaction ComPPI
NUP133 AHCTF1 24234451 24315095 25348397 physical association cross-linking study,electron microscopy,physical interaction ComPPI,IntAct
NUP133 C19ORF53 25348397 N/A physical interaction ComPPI
NUP133 NUP160 11564755 18046405 19706512 24234451 25139911 25348397 27898060 association coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
NUP133 IFI16 25348397 N/A physical interaction ComPPI
NUP133 POM121 25348397 N/A physical interaction ComPPI
NUP133 SENP2 25348397 N/A physical interaction ComPPI
NUP133 RPL26L1 25348397 N/A physical interaction ComPPI
NUP133 TMPO 25348397 N/A physical interaction ComPPI
NUP133 B9D2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NUP133 CDK4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUP133 FOXI2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NUP133 FOXL1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NUP133 FOXP3 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NUP133 FOXQ1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NUP133 PTPMT1 25348397 N/A physical interaction ComPPI
NUP133 SPAST 25348397 N/A physical interaction ComPPI
NUP133 TPTE2 25348397 N/A physical interaction ComPPI
NUP133 RPGRIP1L 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NUP133 BRCA1 25348397 N/A physical interaction ComPPI
NUP133 NXF1 18596238 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NUP133 LRRK2 24234451 24725412 24947832 25348397 association protein array,tandem affinity purification ComPPI,IntAct
NUP133 AAAS 24234451 25348397 27194810 physical association two hybrid,two hybrid array ComPPI,IntAct
NUP133 RAE1 24234451 25348397 27194810 physical association two hybrid,two hybrid array ComPPI,IntAct
NUP133 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
NUP133 TOMM20 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
H1-4 NUP133 24234451 30021884 physical association cross-linking study IntAct
CDK2 NUP133 17360435 27898060 N/A N/A OmniPath

Visualization










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