Gene Information gene info

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GENE：OGDHL

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol OGDHL
FullNmae oxoglutarate dehydrogenase L
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25590
EnsembleID ENSG00000197444
Uniprot Q9ULD0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
OGDHL cuproptosis 36324575 TCA and copper malnutrition-related genes (CDKN2A, IDH1, OGDHL, IDH3G, IDH3B, GLS, DLAT, LIPT1)聽were finally included. copper malnutrition-related genes

Go Annotation:

GeneSymbol Go id
OGDHL GO:0004591,GO:0005515,GO:0005739,GO:0005759,GO:0006096,GO:0006099,GO:0006099,GO:0006103,GO:0030976,GO:0045252,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
OGDHL hsa:55753 path:hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human)
OGDHL hsa:55753 path:hsa00785 Lipoic acid metabolism - Homo sapiens (human)
OGDHL hsa:55753 path:hsa01100 Metabolic pathways - Homo sapiens (human)
OGDHL hsa:55753 path:hsa01200 Carbon metabolism - Homo sapiens (human)
OGDHL hsa:55753 path:hsa01210 2-Oxocarboxylic acid metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
OGDHL STAT3 21988832 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 OGDHL 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 OGDHL 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF OGDHL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 OGDHL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 OGDHL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 OGDHL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS OGDHL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A OGDHL 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 OGDHL 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00002C0FCB OGDHL 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
DLST OGDHL 25361965 interaction type N/A PTMCode2
OGDHL DLST 25361965 interaction type N/A PTMCode2
DLD OGDHL 25361965 interaction type N/A PTMCode2
OGDHL DLD 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SMYD1 OGDHL 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SIAH2 OGDHL 24234451 25348397 25438054 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DLD OGDHL 25348397 N/A physical interaction ComPPI
NFKBIA OGDHL 25348397 N/A physical interaction ComPPI
MDM2 OGDHL 25348397 N/A physical interaction ComPPI
CDK4 OGDHL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STAT3 OGDHL 21988832 24234451 25348397 physical association two hybrid,pull down,physical interaction ComPPI,IntAct
HSCB OGDHL 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
OGDHL ACBD7 25348397 N/A physical interaction ComPPI
OGDHL STAT3 21988832 27898060 N/A N/A OmniPath

Visualization










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