GENE:OSBPL9
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | OSBPL9 |
| FullNmae | oxysterol binding protein like 9 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:16386 |
| EnsembleID | ENSG00000117859 |
| Uniprot | Q96SU4 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| OSBPL9 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| OSBPL9 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| OSBPL9 | cuproptosis | 36010978 | Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. | Cuproptosis-related genes |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| OSBPL9 | GO:0005515,GO:0005794,GO:0005829,GO:0005829,GO:0005829,GO:0006699,GO:0015248,GO:0015248,GO:0015918,GO:0016020,GO:0031902,GO:0032934,GO:0043231,GO:0043231 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | OSBPL9 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | OSBPL9 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | OSBPL9 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | OSBPL9 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | OSBPL9 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | OSBPL9 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | OSBPL9 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | OSBPL9 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | OSBPL9 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | OSBPL9 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | OSBPL9 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | OSBPL9 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | OSBPL9 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | OSBPL9 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | OSBPL9 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | OSBPL9 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | OSBPL9 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | OSBPL9 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | OSBPL9 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000338542 | OSBPL9 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS00001C3AC1 | OSBPL9 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001F0C23 | OSBPL9 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00004719AB | OSBPL9 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B7E30 | OSBPL9 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000028DE3F | OSBPL9 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CF056 | OSBPL9 | 21572407 25416803 | mrna cleavage,inhibition | clip,clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| VAPA | OSBPL9 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NTRK1 | OSBPL9 | 25348397 | N/A | physical interaction | ComPPI |
| CANX | OSBPL9 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| POLD2 | OSBPL9 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | OSBPL9 | 25348397 | N/A | physical interaction | ComPPI |
| RAB5A | OSBPL9 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| CYP1A1 | OSBPL9 | 25348397 | N/A | physical interaction | ComPPI |
| VAPB | OSBPL9 | 19615732 23736259 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct |
| RAB11A | OSBPL9 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| HSPB1 | OSBPL9 | 24234451 25277244 25348397 | physical association | reverse ras recruitment system,physical interaction | ComPPI,IntAct |
| USP11 | OSBPL9 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| GCH1 | OSBPL9 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| COPE | OSBPL9 | 25348397 | N/A | physical interaction | ComPPI |
| DTNBP1 | OSBPL9 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| BLOC1S2 | OSBPL9 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TERF2 | OSBPL9 | 25348397 | N/A | physical interaction | ComPPI |
| TGOLN2 | OSBPL9 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| DNAJA1 | OSBPL9 | 25348397 | N/A | physical interaction | ComPPI |
| HAUS1 | OSBPL9 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CHMP4B | OSBPL9 | 25348397 | N/A | physical interaction | ComPPI |
| FUZ | OSBPL9 | 25348397 | N/A | physical interaction | ComPPI |
| LAMP1 | OSBPL9 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| WRAP73 | OSBPL9 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| OSBPL10 | OSBPL9 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| OSBPL9 | H2BC13 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| OSBPL9 | KBTBD6 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| OSBPL9 | OSBPL11 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| OSBPL9 | CFAP36 | 25348397 | N/A | physical interaction | ComPPI |
| OSBPL9 | OSBPL9 | 19615732 24234451 | physical association | anti tag coimmunoprecipitation | IntAct |
| H2BC14 | OSBPL9 | 24234451 30021884 | physical association | cross-linking study | IntAct |
