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GENE：OXA1L

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol OXA1L
FullNmae OXA1L mitochondrial inner membrane protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8526
EnsembleID ENSG00000155463
Uniprot Q15070

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
OXA1L cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes
OXA1L cuproptosis 36685880 A total of 43 CRGs were manually identified and used to investigate the effects of cuproptosis in HNSC in current study. cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
OXA1L GO:0005515,GO:0005739,GO:0005743,GO:0005759,GO:0009060,GO:0031966,GO:0032780,GO:0032977,GO:0032979,GO:0032981,GO:0032991,GO:0033615,GO:0042803,GO:0051262,GO:0051354,GO:0097177

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
OXA1L hsa:5018 path:hsa03060 Protein export - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 OXA1L 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 OXA1L 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 OXA1L 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 OXA1L 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F4 OXA1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A OXA1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF OXA1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 OXA1L 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 OXA1L 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 OXA1L 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000251D0B OXA1L 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 OXA1L 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002B7450 OXA1L 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A405B OXA1L 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000753AD OXA1L 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F373E OXA1L 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E OXA1L 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000048D44E OXA1L 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 OXA1L 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005CE28 OXA1L 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEF5F OXA1L 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA OXA1L 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF OXA1L 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
OXA1L MRPL48 25361965 interaction type N/A PTMCode2
MRPL48 OXA1L 25361965 interaction type N/A PTMCode2
OXA1L CYC1 25361965 interaction type N/A PTMCode2
CYC1 OXA1L 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CHCHD2 OXA1L 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
ATP5F1B OXA1L 25348397 N/A physical interaction ComPPI
MRPL28 OXA1L 25348397 N/A physical interaction ComPPI
MRPL23 OXA1L 25348397 N/A physical interaction ComPPI
NDUFAF4 OXA1L 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
CBLC OXA1L 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RHOT2 OXA1L 25348397 N/A physical interaction ComPPI
ILK OXA1L 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ABCC2 OXA1L 25348397 N/A physical interaction ComPPI
TRIM25 OXA1L 25348397 N/A physical interaction ComPPI
FAF2 OXA1L 25348397 N/A physical interaction ComPPI
AGO2 OXA1L 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
EYA2 OXA1L 25348397 N/A physical interaction ComPPI
TOMM40 OXA1L 25348397 N/A physical interaction ComPPI
MTM1 OXA1L 25348397 N/A physical interaction ComPPI
MRPL20 OXA1L 25348397 N/A physical interaction ComPPI
COQ9 OXA1L 25348397 N/A physical interaction ComPPI
SDHB OXA1L 25348397 N/A physical interaction ComPPI
NXF1 OXA1L 25348397 N/A physical interaction ComPPI
MOV10 OXA1L 25348397 N/A physical interaction ComPPI
COX6B1 OXA1L 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
GAN OXA1L 25348397 N/A physical interaction ComPPI
OXA1L MRPL13 25348397 N/A physical interaction ComPPI
OXA1L MRPL48 25348397 N/A physical interaction ComPPI
OXA1L MRPL49 25348397 N/A physical interaction ComPPI
OXA1L MRPL51 25348397 N/A physical interaction ComPPI
OXA1L MRPL58 25348397 N/A physical interaction ComPPI
OXA1L IKBIP 25348397 N/A physical interaction ComPPI
OXA1L FRMD3 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
OXA1L MRPL50 25348397 N/A physical interaction ComPPI
OXA1L NDUFA4 25348397 N/A physical interaction ComPPI
OXA1L PTPMT1 25348397 N/A physical interaction ComPPI
OXA1L CHCHD10 25348397 N/A physical interaction ComPPI
OXA1L TTC30B 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
OXA1L MICOS13 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
HSCB OXA1L 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct

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