Gene Information gene info

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GENE：PCGF6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PCGF6
FullNmae polycomb group ring finger 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21156
EnsembleID ENSG00000156374
Uniprot Q9BYE7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PCGF6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PCGF6 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
PCGF6 GO:0000122,GO:0005515,GO:0005634,GO:0005654,GO:0006338,GO:0006357,GO:0031519,GO:0035102,GO:0035102,GO:0036353,GO:0045892,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PCGF6 hsa:84108 path:hsa03083 Polycomb repressive complex - Homo sapiens (human)
PCGF6 hsa:84108 path:hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 PCGF6 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 PCGF6 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PCGF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PCGF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PCGF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PCGF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PCGF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004DA9DB PCGF6 22291592 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK7 PCGF6 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
CBX8 PCGF6 21282530 24234451 25348397 27705803 association pull down,physical interaction,tandem affinity purification ComPPI,IntAct
ZKSCAN1 PCGF6 25348397 N/A physical interaction ComPPI
CDC42 PCGF6 25348397 N/A two hybrid ComPPI
MAGEA1 PCGF6 25348397 N/A physical interaction ComPPI
EIF2B2 PCGF6 25348397 N/A physical interaction ComPPI
E2F6 PCGF6 24234451 25348397 27705803 association physical interaction,in vitro,tandem affinity purification ComPPI,IntAct
BMI1 PCGF6 25348397 N/A physical interaction ComPPI
RING1 PCGF6 22493164 24234451 25348397 27705803 association,physical association two hybrid,physical interaction,two hybrid array,tandem affinity purification ComPPI,IntAct
RYBP PCGF6 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
HSP90AB1 PCGF6 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
PNMA1 PCGF6 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MAGEC2 PCGF6 25348397 N/A physical interaction ComPPI
CBX1 PCGF6 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
USP7 PCGF6 25348397 N/A physical interaction ComPPI
PEX10 PCGF6 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HSP90AA1 PCGF6 25348397 N/A physical interaction ComPPI
APBB1 PCGF6 25348397 N/A physical interaction ComPPI
CSNK2A1 PCGF6 25348397 N/A physical interaction ComPPI
RAD18 PCGF6 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ARG1 PCGF6 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
CBX4 PCGF6 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
CSNK2A2 PCGF6 25348397 N/A physical interaction ComPPI
CBX5 PCGF6 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
H3-4 PCGF6 25348397 N/A physical interaction ComPPI
HDAC2 PCGF6 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
TCP1 PCGF6 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
CCT5 PCGF6 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
CCT7 PCGF6 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
MXD1 PCGF6 25348397 N/A physical interaction ComPPI
RNF2 PCGF6 12183370 14525934 22493164 24234451 25348397 26496610 27705803 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,tandem affinity purification,two hybrid ComPPI,HPRD,IntAct
TFDP1 PCGF6 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
TRIM28 PCGF6 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TFDP2 PCGF6 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
CDK7 PCGF6 12167161 14525934 24234451 25348397 29568061 association experimental interaction detection,in vitro,in vivo,proximity-dependent biotin identification ComPPI,HPRD,IntAct
EED PCGF6 25348397 N/A physical interaction ComPPI
USP33 PCGF6 25348397 N/A physical interaction ComPPI
H3C1 PCGF6 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ZBTB33 PCGF6 25348397 N/A physical interaction ComPPI
TIMM8A PCGF6 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TIMM13 PCGF6 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
UBE2D3 PCGF6 25348397 N/A physical interaction ComPPI
YAF2 PCGF6 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
SS18L1 PCGF6 25348397 N/A physical interaction ComPPI
TRIM25 PCGF6 25348397 N/A physical interaction ComPPI
PSME3 PCGF6 25348397 N/A physical interaction ComPPI
ELAVL1 PCGF6 25348397 N/A physical interaction ComPPI
CBX7 PCGF6 21282530 24234451 25348397 27705803 association pull down,physical interaction,tandem affinity purification ComPPI,IntAct
CARD8 PCGF6 25348397 N/A physical interaction ComPPI
RPP38 PCGF6 25348397 N/A physical interaction ComPPI
PRKAB1 PCGF6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PCGF6 KDM5D 14525934 17320162 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PCGF6 CBX3 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
PCGF6 UBE2U 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PCGF6 MAX 24234451 25348397 25609649 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
PCGF6 L3MBTL2 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
PCGF6 MGA 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
PCGF6 HDAC1 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
PCGF6 USP2 25348397 N/A physical interaction ComPPI
PCGF6 USP21 25348397 N/A physical interaction ComPPI
PCGF6 HSP90AA2P 25348397 N/A physical interaction ComPPI
PCGF6 CBX6 21282530 24234451 25348397 N/A pull down,physical interaction ComPPI,IntAct
PCGF6 WBP2NL 25348397 N/A physical interaction ComPPI
PCGF6 CEP170B 25348397 N/A physical interaction ComPPI
PCGF6 WDR76 25348397 N/A physical interaction ComPPI
PCGF6 CEP78 25348397 N/A physical interaction ComPPI
PCGF6 RICTOR 25348397 N/A physical interaction ComPPI
PCGF6 EFL1 25348397 N/A physical interaction ComPPI
PCGF6 MSANTD2 25348397 N/A physical interaction ComPPI
PCGF6 ELP3 25348397 N/A physical interaction ComPPI
PCGF6 DDX51 25348397 N/A physical interaction ComPPI
PCGF6 MIER2 25348397 N/A physical interaction ComPPI
PCGF6 AUTS2 24234451 25348397 25519132 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
PCGF6 MAGEE2 25348397 N/A physical interaction ComPPI
PCGF6 MAGEL2 25348397 N/A physical interaction ComPPI
PCGF6 ZNF526 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PCGF6 BCORL1 25348397 N/A physical interaction ComPPI
PCGF6 FBRS 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
PCGF6 ZNF644 25348397 N/A physical interaction ComPPI
PCGF6 CORO6 25348397 N/A physical interaction ComPPI
PCGF6 CSNK2B 25348397 N/A physical interaction ComPPI
PCGF6 TULP3 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
PCGF6 FBRSL1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PCGF6 CCT3 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PCGF6 CCT2 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PCGF6 CCT8 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PCGF6 CCT4 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PCGF6 CCT6A 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PCGF6 DCAF7 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
WDR5 PCGF6 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
CDK7 PCGF6 12167161 27898060 N/A N/A OmniPath

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