Gene Information gene info

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GENE：PCMT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PCMT1
FullNmae protein-L-isoaspartate (D-aspartate) O-methyltransferase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8728
EnsembleID ENSG00000120265
Uniprot P22061

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PCMT1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PCMT1 cuproptosis 36550822 Next, 11 hub CAGs(cuproptosis-associated genes), including COPB2, MRPL39, PGK1, PRDX1, PCMT1, MPZL3, LACTB2, HSPH1, DIP2B, DLG3, and NFKBIA, were applied to construct a novel prognostic risk signature for BR. cuproptosis-associated gene

Go Annotation:

GeneSymbol Go id
PCMT1 GO:0004719,GO:0004719,GO:0004719,GO:0005515,GO:0005737,GO:0005829,GO:0005829,GO:0006479,GO:0030091,GO:0045296,GO:0070062,GO:1903561

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PCMT1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PCMT1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PCMT1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PCMT1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PCMT1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PCMT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PCMT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PCMT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PCMT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 PCMT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PCMT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PCMT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PCMT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC PCMT1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070B1D PCMT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000600E6 PCMT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000171CD1 PCMT1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C PCMT1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D PCMT1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000007A060 PCMT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F PCMT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000250A40 PCMT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000411672 PCMT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000031D186 PCMT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075BEA7 PCMT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000572E11 PCMT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000028D811 PCMT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED PCMT1 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
KLHL42 PCMT1 25348397 N/A physical interaction ComPPI
AIMP2 PCMT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EIF1B PCMT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PAK2 PCMT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
LDHB PCMT1 25348397 N/A physical interaction ComPPI
TP53BP1 PCMT1 25348397 N/A physical interaction ComPPI
TRAF6 PCMT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
LMNA PCMT1 24234451 25348397 29568061 association pull down,physical interaction ComPPI,IntAct
GABARAPL2 PCMT1 17353931 20562859 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
KEAP1 PCMT1 25348397 N/A physical interaction ComPPI
MCM2 PCMT1 25348397 N/A physical interaction ComPPI
MAP1LC3B PCMT1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
KBTBD7 PCMT1 25348397 N/A physical interaction ComPPI
COX17 PCMT1 25348397 N/A physical interaction ComPPI
GRB2 PCMT1 12577067 24234451 25348397 association pull down ComPPI,IntAct
JUN PCMT1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
CREBBP PCMT1 11912212 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
COPS5 PCMT1 25348397 N/A physical interaction ComPPI
CUL3 PCMT1 25348397 N/A physical interaction ComPPI
SCYL2 PCMT1 25348397 N/A physical interaction ComPPI
UBC PCMT1 25348397 N/A physical interaction ComPPI
DLD PCMT1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
APOA1 PCMT1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NTRK1 PCMT1 25348397 N/A physical interaction ComPPI
ENO1 PCMT1 25348397 N/A physical interaction ComPPI
CDH1 PCMT1 25348397 N/A physical interaction ComPPI
PTPN1 PCMT1 25348397 N/A physical interaction ComPPI
CSNK1E PCMT1 25348397 N/A physical interaction ComPPI
APOE PCMT1 25348397 N/A physical interaction ComPPI
PTPRB PCMT1 24234451 25348397 28330616 association pull down ComPPI,IntAct
CFTR PCMT1 17110338 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
AKR1B1 PCMT1 25348397 N/A physical interaction ComPPI
RAB3IP PCMT1 25348397 N/A physical interaction ComPPI
RAB5A PCMT1 24234451 25348397 29568061 association pull down ComPPI,IntAct
EEA1 PCMT1 24234451 25348397 29568061 association pull down ComPPI,IntAct
GDI1 PCMT1 25348397 N/A physical interaction ComPPI
TNIK PCMT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TRAP1 PCMT1 25348397 N/A physical interaction ComPPI
RRM2 PCMT1 25348397 N/A physical interaction ComPPI
HUWE1 PCMT1 25348397 N/A physical interaction ComPPI
RAD23A PCMT1 25348397 N/A physical interaction ComPPI
ZRANB2 PCMT1 25348397 N/A physical interaction ComPPI
CUL2 PCMT1 25348397 N/A physical interaction ComPPI
SPR PCMT1 25348397 N/A physical interaction ComPPI
ABI1 PCMT1 25348397 N/A physical interaction ComPPI
CDK2 PCMT1 25348397 N/A physical interaction ComPPI
CUL1 PCMT1 25348397 N/A physical interaction ComPPI
VHL PCMT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMP2 PCMT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ABI2 PCMT1 25348397 N/A physical interaction ComPPI
HDAC6 PCMT1 25348397 N/A physical interaction ComPPI
MAP1LC3A PCMT1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
AURKA PCMT1 25348397 N/A physical interaction ComPPI
RIPK2 PCMT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
VCAM1 PCMT1 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
ITGA4 PCMT1 25348397 N/A physical interaction ComPPI
DNM1L PCMT1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CUL7 PCMT1 25348397 N/A physical interaction ComPPI
HDAC5 PCMT1 25348397 N/A physical interaction ComPPI
BCOR PCMT1 25348397 N/A physical interaction ComPPI
CAND1 PCMT1 25348397 N/A physical interaction ComPPI
SVIL PCMT1 25348397 N/A physical interaction ComPPI
CD40 PCMT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NFKB1 PCMT1 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
PCMT1 CHD3 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PCMT1 TERF1 25348397 N/A physical interaction ComPPI
PCMT1 TERF2 25348397 N/A physical interaction ComPPI
PCMT1 POT1 25348397 N/A physical interaction ComPPI
PCMT1 DYRK2 25348397 N/A physical interaction ComPPI
PCMT1 PPIH 25348397 N/A physical interaction ComPPI
PCMT1 TPM4 25348397 N/A physical interaction ComPPI
PCMT1 PSMB7 25348397 N/A physical interaction ComPPI
PCMT1 PFDN2 25348397 N/A physical interaction ComPPI
PCMT1 SEC24A 25348397 N/A physical interaction ComPPI
PCMT1 NOTCH2 25348397 N/A physical interaction ComPPI
PCMT1 UCHL3 25348397 N/A physical interaction ComPPI
PCMT1 SDHAF2 25348397 N/A physical interaction ComPPI
PCMT1 UBE2C 25348397 N/A physical interaction ComPPI
PCMT1 FN1 25348397 N/A physical interaction ComPPI
PCMT1 SH3RF2 25348397 N/A physical interaction ComPPI
PCMT1 TP53 25348397 N/A physical interaction ComPPI
PCMT1 OBSL1 25348397 N/A physical interaction ComPPI
PCMT1 PDPR 25348397 N/A physical interaction ComPPI
PCMT1 DTYMK 25348397 N/A physical interaction ComPPI
PCMT1 KLHL24 25348397 N/A physical interaction ComPPI
PCMT1 KBTBD6 25348397 N/A physical interaction ComPPI
PCMT1 KLHL26 25348397 N/A physical interaction ComPPI
PCMT1 KLHL18 25348397 N/A physical interaction ComPPI
PCMT1 RPS6KB2 25348397 N/A physical interaction ComPPI
PCMT1 CSTB 25348397 N/A physical interaction ComPPI
PCMT1 ENO2 25348397 N/A physical interaction ComPPI
PCMT1 MTAP 25348397 N/A physical interaction ComPPI
PCMT1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PCMT1 TKT 25348397 N/A physical interaction ComPPI
PCMT1 PRDX2 25348397 N/A physical interaction ComPPI
PCMT1 UFC1 25348397 N/A physical interaction ComPPI
PCMT1 YKT6 25348397 N/A physical interaction ComPPI
PCMT1 KLC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PCMT1 PCGF1 25348397 N/A physical interaction ComPPI
PCMT1 NANOG 25348397 N/A physical interaction ComPPI
PCMT1 POU5F1 25348397 N/A physical interaction ComPPI
PCMT1 COPS7B 25348397 N/A physical interaction ComPPI
PCMT1 SSH3 25348397 N/A physical interaction ComPPI
PCMT1 DLST 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PCMT1 TRIM25 25348397 N/A physical interaction ComPPI
PCMT1 BRCA1 25348397 N/A physical interaction ComPPI
PCMT1 MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PCMT1 ATG5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PCMT1 DEGS1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PCMT1 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PCMT1 IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PCMT1 EPB41 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PCMT1 PPP2R2B 25348397 N/A pull down ComPPI
MIF PCMT1 25348397 N/A physical interaction ComPPI
ATP6V1B2 PCMT1 25348397 N/A physical interaction ComPPI
SMARCB1 PCMT1 24234451 30108113 association pull down,proximity-dependent biotin identification IntAct
AGTR1 PCMT1 24234451 28298427 physical association ubiquitin reconstruction IntAct
CCR2 PCMT1 24234451 28298427 physical association ubiquitin reconstruction IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B4F4B PCMT1 27087310 direct interaction,inhibition N/A NPInter

Visualization










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