GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
PDZD4
FullNmae
PDZ domain containing 4
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:21167
EnsembleID
ENSG00000067840
Uniprot
Q76G19
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
PDZD4
cuproptosis
36010978
Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1.
Cuproptosis-related genes
Go Annotation:
GeneSymbol
Go id
PDZD4
GO:0005938,GO:0006508
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
APP
PDZD4
21832049
23180781
physical association
protein array
InnateDB
Source
Target
Pmid
Interactiontype
Methods
Database
ETS1
PDZD4
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
EGR1
PDZD4
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS0000237AF9
PDZD4
18185580
25416803
mrna cleavage,inhibition
array technology
TarBase
URS00002394F5
PDZD4
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS00004929F1
PDZD4
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS00002373FD
PDZD4
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000077DDE
PDZD4
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000C403E
PDZD4
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS000076B539
PDZD4
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000046CDA6
PDZD4
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00002367FA
PDZD4
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00000B989F
PDZD4
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00006097A6
PDZD4
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
GFI1B
PDZD4
14525934
16713569
24234451
25348397
physical association
two hybrid,physical interaction,two hybrid
ComPPI,HPRD,IntAct
APIP
PDZD4
25348397
N/A
physical interaction
ComPPI
PDZD4
APP
25348397
N/A
physical interaction
ComPPI
Visualization