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GENE：PHF5A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PHF5A
FullNmae PHD finger protein 5A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18000
EnsembleID ENSG00000100410
Uniprot Q7RTV0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PHF5A cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
PHF5A GO:0000398,GO:0000398,GO:0000398,GO:0003677,GO:0003723,GO:0003723,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005681,GO:0005684,GO:0005686,GO:0005686,GO:0005686,GO:0005689,GO:0005689,GO:0008270,GO:0016363,GO:0016607,GO:0045893,GO:0048863,GO:0071005,GO:0071011,GO:1903241

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PHF5A hsa:84844 path:hsa03040 Spliceosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EZH2 PHF5A 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
SUZ12 PHF5A 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 PHF5A 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
BMI1 PHF5A 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
FOXP3 PHF5A 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PHF5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PHF5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PHF5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PHF5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PHF5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000239117 PHF5A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AD002 PHF5A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 PHF5A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 PHF5A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F PHF5A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 PHF5A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 PHF5A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB0E PHF5A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 PHF5A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000AB32B PHF5A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001A6D0C PHF5A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 PHF5A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B PHF5A 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003D8730 PHF5A 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075A513 PHF5A 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000010F787 PHF5A 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 PHF5A 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PHF5A SF3A2 25361965 interaction type N/A PTMCode2
SF3A2 PHF5A 25361965 interaction type N/A PTMCode2
PHF5A SF3B3 25361965 interaction type N/A PTMCode2
SF3B3 PHF5A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNRPB2 PHF5A 25348397 N/A physical interaction ComPPI
CD2BP2 PHF5A 25348397 N/A physical interaction ComPPI
SNRPA1 PHF5A 25348397 N/A physical interaction ComPPI
FOXB1 PHF5A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BMI1 PHF5A 25348397 N/A physical interaction ComPPI
MCM2 PHF5A 25348397 N/A physical interaction ComPPI
SF3B4 PHF5A 25348397 N/A physical interaction ComPPI
EMC2 PHF5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EZH2 PHF5A 25348397 N/A physical interaction ComPPI
SF3A2 PHF5A 17332742 24234451 25348397 physical association affinity chromatography technology,physical interaction ComPPI,IntAct
CHST15 PHF5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SF3B1 PHF5A 25348397 N/A physical interaction ComPPI
SFPQ PHF5A 25348397 N/A physical interaction ComPPI
YBX1 PHF5A 25348397 N/A physical interaction ComPPI
PDHA1 PHF5A 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SUMO2 PHF5A 25348397 N/A physical interaction ComPPI
ZDHHC17 PHF5A 24234451 24705354 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RNF2 PHF5A 25348397 N/A physical interaction ComPPI
VCAM1 PHF5A 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
H3C1 PHF5A 25348397 N/A physical interaction ComPPI
PPP4R2 PHF5A 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
S100A10 PHF5A 25348397 N/A physical interaction ComPPI
PPP3CB PHF5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SF3B3 PHF5A 25348397 N/A physical interaction ComPPI
AGO1 PHF5A 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SRPK3 PHF5A 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SUZ12 PHF5A 25348397 N/A physical interaction ComPPI
SF3B6 PHF5A 25348397 N/A physical interaction ComPPI
SF3B2 PHF5A 25348397 N/A physical interaction ComPPI
HNRNPA1 PHF5A 25348397 N/A physical interaction ComPPI
PPP2R2D PHF5A 24234451 25348397 28330616 association pull down ComPPI,IntAct
DDX23 PHF5A 25348397 N/A physical interaction ComPPI
RBM25 PHF5A 25348397 N/A physical interaction ComPPI
NCL PHF5A 25348397 N/A physical interaction ComPPI
PRPF31 PHF5A 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PHF5A SF3B5 25348397 N/A physical interaction ComPPI
PHF5A DHX8 25348397 N/A physical interaction ComPPI
PHF5A PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PHF5A ZC3H18 24234451 25348397 29298432 association anti tag coimmunoprecipitation ComPPI,IntAct

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