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GENE：PITRM1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PITRM1
FullNmae pitrilysin metallopeptidase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17663
EnsembleID ENSG00000107959
Uniprot Q5JRX3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PITRM1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
PITRM1 GO:0004222,GO:0004222,GO:0004222,GO:0005739,GO:0005759,GO:0005759,GO:0005759,GO:0006508,GO:0006508,GO:0006626,GO:0008047,GO:0008237,GO:0008270,GO:0016485

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 PITRM1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PITRM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PITRM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PITRM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PITRM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PITRM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PITRM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PITRM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 PITRM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PITRM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PITRM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PITRM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000032FC1A PITRM1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000544FF1 PITRM1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 PITRM1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 PITRM1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
ARPC3 PITRM1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CHCHD2 PITRM1 25348397 N/A physical interaction ComPPI
VASP PITRM1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PAK5 PITRM1 25348397 N/A physical interaction ComPPI
VAPB PITRM1 25348397 N/A physical interaction ComPPI
CCL22 PITRM1 25348397 N/A physical interaction ComPPI
PRDX6 PITRM1 25348397 N/A physical interaction ComPPI
RIF1 PITRM1 25348397 N/A physical interaction ComPPI
PRKCSH PITRM1 25348397 N/A physical interaction ComPPI
TERF2 PITRM1 25348397 N/A physical interaction ComPPI
NDUFV2 PITRM1 25348397 N/A physical interaction ComPPI
SLC25A10 PITRM1 25348397 N/A physical interaction ComPPI
MRPL12 PITRM1 25348397 N/A physical interaction ComPPI
UFM1 PITRM1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DDX41 PITRM1 25348397 N/A physical interaction ComPPI
PITRM1 NDUFS3 25348397 N/A physical interaction ComPPI
PITRM1 PPM1K 25348397 N/A physical interaction ComPPI
PITRM1 SIRT4 24234451 25348397 25525879 association anti tag coimmunoprecipitation ComPPI,IntAct

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