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GENE：PLOD1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PLOD1
FullNmae procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9081
EnsembleID ENSG00000083444
Uniprot Q02809

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PLOD1 cuproptosis 36505872 A total of 44 cuproptosis-related genes were extracted from known literature. cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
PLOD1 GO:0001666,GO:0005506,GO:0005515,GO:0005783,GO:0005789,GO:0008475,GO:0008475,GO:0008475,GO:0008475,GO:0008544,GO:0017185,GO:0017185,GO:0017185,GO:0030867,GO:0031418,GO:0070062,GO:1902494

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PLOD1 hsa:5351 path:hsa00310 Lysine degradation - Homo sapiens (human)
PLOD1 hsa:5351 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ISG15 PLOD1 16009940 23180781 physical association unspecified method InnateDB

Source Target Pmid Interactiontype Methods Database
AR PLOD1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 PLOD1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A PLOD1 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PLOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PLOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PLOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PLOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PLOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PLOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PLOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PLOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PITX2 PLOD1 21837767 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 PLOD1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 PLOD1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00005651EE PLOD1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D PLOD1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000183BED PLOD1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CUL5 PLOD1 25348397 N/A physical interaction ComPPI
CDCA3 PLOD1 25348397 N/A physical interaction ComPPI
ISG15 PLOD1 25348397 N/A physical interaction ComPPI
GABARAPL2 PLOD1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DCUN1D1 PLOD1 25348397 N/A physical interaction ComPPI
HNRNPH2 PLOD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLOD3 PLOD1 20955792 25348397 27898060 N/A anti tag coimmunoprecipitation ComPPI,OmniPath
NFATC1 PLOD1 25348397 N/A physical interaction ComPPI
COL4A5 PLOD1 25348397 N/A physical interaction ComPPI
COL4A6 PLOD1 25348397 N/A physical interaction ComPPI
COPS5 PLOD1 25348397 N/A physical interaction ComPPI
CUL3 PLOD1 25348397 N/A physical interaction ComPPI
PDIA3 PLOD1 17170699 24234451 25348397 disulfide bond anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COL6A2 PLOD1 25348397 N/A physical interaction ComPPI
P3H4 PLOD1 25348397 N/A physical interaction ComPPI
NTRK1 PLOD1 25348397 N/A physical interaction ComPPI
COL4A2 PLOD1 25348397 N/A physical interaction ComPPI
HNRNPL PLOD1 25348397 N/A physical interaction ComPPI
COLQ PLOD1 25348397 N/A physical interaction ComPPI
ALG13 PLOD1 25348397 N/A physical interaction ComPPI
USP4 PLOD1 25348397 N/A physical interaction ComPPI
NAE1 PLOD1 25348397 N/A physical interaction ComPPI
CUL2 PLOD1 25348397 N/A physical interaction ComPPI
CUL4B PLOD1 25348397 N/A physical interaction ComPPI
GEMIN5 PLOD1 25348397 N/A physical interaction ComPPI
ODF2 PLOD1 25348397 N/A physical interaction ComPPI
CUL1 PLOD1 25348397 N/A physical interaction ComPPI
COL4A1 PLOD1 25348397 N/A physical interaction ComPPI
GABARAP PLOD1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MAP1LC3A PLOD1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CAND1 PLOD1 25348397 N/A physical interaction ComPPI
TJP2 PLOD1 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
FOXA1 PLOD1 25348397 N/A physical interaction ComPPI
PTPRN PLOD1 25348397 N/A physical interaction ComPPI
COL2A1 PLOD1 25348397 N/A physical interaction ComPPI
DDX1 PLOD1 25348397 N/A physical interaction ComPPI
HNRNPH1 PLOD1 25348397 N/A physical interaction ComPPI
PLK4 PLOD1 25348397 N/A physical interaction ComPPI
H2AX PLOD1 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COL1A1 PLOD1 25348397 N/A physical interaction ComPPI
TERF1 PLOD1 25348397 N/A physical interaction ComPPI
KIF1B PLOD1 25348397 N/A physical interaction ComPPI
MAP3K3 PLOD1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TERF2 PLOD1 25348397 N/A physical interaction ComPPI
DUSP11 PLOD1 25348397 N/A physical interaction ComPPI
RBM7 PLOD1 25348397 N/A physical interaction ComPPI
NCDN PLOD1 25348397 N/A physical interaction ComPPI
COL18A1 PLOD1 25348397 N/A physical interaction ComPPI
LATS2 PLOD1 25348397 N/A physical interaction ComPPI
COL6A1 PLOD1 25348397 N/A physical interaction ComPPI
POR PLOD1 25348397 N/A physical interaction ComPPI
HNRNPA1 PLOD1 25348397 N/A physical interaction ComPPI
GABARAPL1 PLOD1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
COL14A1 PLOD1 25348397 N/A physical interaction ComPPI
OFD1 PLOD1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SIRT7 PLOD1 25348397 N/A physical interaction ComPPI
MEX3D PLOD1 25348397 N/A physical interaction ComPPI
FBXO6 PLOD1 25348397 N/A physical interaction ComPPI
ZNF106 PLOD1 25348397 N/A physical interaction ComPPI
PLOD1 OBSL1 25348397 N/A physical interaction ComPPI
PLOD1 COLGALT1 25348397 N/A physical interaction ComPPI
PLOD1 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLOD1 RPGRIP1L 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLOD1 TCTN1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLOD1 COL5A1 25348397 N/A physical interaction ComPPI
PLOD1 PABIR2 25348397 N/A physical interaction ComPPI
PLOD1 C9ORF40 25348397 N/A physical interaction ComPPI
PLOD1 CHERP 25348397 N/A physical interaction ComPPI
PLOD1 KIF18B 25348397 N/A physical interaction ComPPI
PLOD1 PRRC2B 25348397 N/A physical interaction ComPPI
PLOD1 P3H3 25348397 N/A physical interaction ComPPI
PLOD1 U2SURP 25348397 N/A physical interaction ComPPI
PLOD1 KDM3B 25348397 N/A physical interaction ComPPI
PLOD1 RNF169 21252943 24234451 25348397 association pull down ComPPI,IntAct
PLOD2 PLOD1 25348397 N/A physical interaction ComPPI
BIRC2 PLOD1 24234451 30561431 association virotrap IntAct
TRADD PLOD1 24234451 30561431 association virotrap IntAct
PLOD1 WDFY4 24234451 30021884 physical association cross-linking study IntAct
PLOD1 LRRC47 24234451 30021884 physical association cross-linking study IntAct
ISG15 PLOD1 16009940 27898060 N/A N/A OmniPath

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