Gene Information gene info

  1. Home

GENE：PMVK

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PMVK
FullNmae phosphomevalonate kinase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9141
EnsembleID ENSG00000163344
Uniprot Q15126

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PMVK immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PMVK cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
PMVK GO:0004631,GO:0004631,GO:0004631,GO:0005515,GO:0005524,GO:0005777,GO:0005829,GO:0005829,GO:0006695,GO:0006695,GO:0006695,GO:0016020,GO:0016126,GO:0016310,GO:0019287,GO:0019287,GO:0070062,GO:0070723

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PMVK hsa:10654 path:hsa00900 Terpenoid backbone biosynthesis - Homo sapiens (human)
PMVK hsa:10654 path:hsa01100 Metabolic pathways - Homo sapiens (human)
PMVK hsa:10654 path:hsa04146 Peroxisome - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 PMVK 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PMVK 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP73 PMVK 21245298 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PMVK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PMVK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PMVK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PMVK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PMVK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PMVK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PMVK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PMVK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PMVK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC PMVK N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
PITPNA PMVK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GTF2E2 PMVK 25348397 N/A physical interaction ComPPI
VCAM1 PMVK 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
NPPA PMVK 25348397 N/A physical interaction ComPPI
SSB PMVK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
FGB PMVK 25348397 N/A physical interaction ComPPI
TBPL1 PMVK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RGS20 PMVK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
FYTTD1 PMVK 25348397 N/A physical interaction ComPPI
SCNM1 PMVK 25348397 N/A physical interaction ComPPI
NKD2 PMVK 25348397 N/A physical interaction ComPPI
MLF2 PMVK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PMVK SETD3 25348397 N/A physical interaction ComPPI
PMVK SDHA 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PMVK MCPH1 25348397 N/A physical interaction ComPPI
SNRNP27 PMVK 25348397 N/A physical interaction ComPPI
MKI67 PMVK 24234451 26949251 association anti tag coimmunoprecipitation IntAct

Visualization










  Return