Gene Information gene info

  1. Home

GENE：POLR2K

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol POLR2K
FullNmae RNA polymerase II, I and III subunit K
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9198
EnsembleID ENSG00000147669
Uniprot P53803

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
POLR2K cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
POLR2K GO:0001054,GO:0001055,GO:0001056,GO:0003677,GO:0005515,GO:0005634,GO:0005654,GO:0005665,GO:0005665,GO:0005666,GO:0005736,GO:0005829,GO:0006356,GO:0006360,GO:0006366,GO:0006383,GO:0008270

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
POLR2K hsa:5440 path:hsa03020 RNA polymerase - Homo sapiens (human)
POLR2K hsa:5440 path:hsa03420 Nucleotide excision repair - Homo sapiens (human)
POLR2K hsa:5440 path:hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human)
POLR2K hsa:5440 path:hsa05016 Huntington disease - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP POLR2K 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 POLR2K 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink

Source Target Pmid Interactiontype Methods Database
SH3KBP1 POLR2K 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SRC POLR2K 25348397 N/A physical interaction ComPPI
PSMB9 POLR2K 25348397 N/A physical interaction ComPPI
XPO1 POLR2K 25348397 N/A physical interaction ComPPI
POLR3E POLR2K 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR2E POLR2K 14525934 24234451 25348397 27193682 9201987 physical association experimental interaction detection,physical interaction,electron tomography,in vitro ComPPI,HPRD,IntAct
POLR2A POLR2K 25348397 N/A physical interaction ComPPI
MED26 POLR2K 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELOA POLR2K 25348397 N/A physical interaction ComPPI
ESR1 POLR2K 25348397 N/A physical interaction ComPPI
BRCA1 POLR2K 10725406 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
POLR2K SMYD3 14525934 15235609 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
POLR2K POLR2C 14525934 25348397 9201987 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
POLR2K POLR2H 14525934 25348397 9201987 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
POLR2K POLR2D 10567706 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
POLR2K MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR2K POLR2B 25348397 N/A physical interaction ComPPI
POLR2K POLR2F 25348397 N/A physical interaction ComPPI
POLR2K POLR2G 25348397 N/A physical interaction ComPPI
POLR2K APP 25348397 N/A physical interaction ComPPI
POLR2K MED19 25348397 N/A physical interaction ComPPI
POLR2K MOV10 25348397 N/A physical interaction ComPPI
POLR2K POLR1C 25348397 N/A physical interaction ComPPI
POLR2K POLR2I 25348397 N/A physical interaction ComPPI
POLR2K ERCC2 24234451 25348397 27193682 physical association electron tomography ComPPI,IntAct
POLR2J POLR2K 25348397 N/A physical interaction ComPPI
POLR1A POLR2K 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR2K POLR2K 14525934 9201987 N/A experimental interaction detection HPRD
APP POLR2K 21832049 27898060 N/A N/A OmniPath
POLR2K APP 21832049 27898060 N/A N/A OmniPath

Visualization










  Return