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GENE：PPAT

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PPAT
FullNmae phosphoribosyl pyrophosphate amidotransferase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9238
EnsembleID ENSG00000128059
Uniprot Q06203

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PPAT mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PPAT immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PPAT cuproptosis 36685880 A total of 43 CRGs were manually identified and used to investigate the effects of cuproptosis in HNSC in current study. cuproptosis-related genes
PPAT cuproptosis 36505872 A total of 44 cuproptosis-related genes were extracted from known literature. cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
PPAT GO:0004044,GO:0005829,GO:0006164,GO:0006177,GO:0006189,GO:0006541,GO:0009113,GO:0044208,GO:0046872,GO:0051539,GO:0097294

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PPAT hsa:5471 path:hsa00230 Purine metabolism - Homo sapiens (human)
PPAT hsa:5471 path:hsa00250 Alanine, aspartate and glutamate metabolism - Homo sapiens (human)
PPAT hsa:5471 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MYC PPAT 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PPAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PPAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PPAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PPAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PPAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PPAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PPAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PPAT N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 PPAT 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 PPAT 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS0000122ED0 PPAT 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 PPAT 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000048BA36 PPAT 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CIAO1 PPAT 25348397 N/A physical interaction ComPPI
IMPDH2 PPAT 25348397 N/A physical interaction ComPPI
ATXN1 PPAT 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
PAK1 PPAT 25348397 N/A physical interaction ComPPI
HDAC3 PPAT 25348397 N/A physical interaction ComPPI
ARHGAP1 PPAT 25348397 N/A physical interaction ComPPI
NTRK1 PPAT 25348397 N/A physical interaction ComPPI
SNX2 PPAT 25348397 N/A physical interaction ComPPI
ILK PPAT 25348397 N/A physical interaction ComPPI
PPP2CA PPAT 25348397 N/A physical interaction ComPPI
HSPA4 PPAT 25348397 N/A physical interaction ComPPI
MMS19 PPAT 24234451 25348397 28178521 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
B2M PPAT 25348397 N/A physical interaction ComPPI
PRPS1 PPAT 25348397 N/A physical interaction ComPPI
PRPS2 PPAT 25348397 N/A physical interaction ComPPI
CARM1 PPAT 25348397 N/A physical interaction ComPPI
SMURF1 PPAT 25348397 N/A physical interaction ComPPI
MCM3 PPAT 25348397 N/A physical interaction ComPPI
CRY1 PPAT 25348397 N/A physical interaction ComPPI
FBXW11 PPAT 25348397 N/A physical interaction ComPPI
RSU1 PPAT 25348397 N/A physical interaction ComPPI
MEA1 PPAT 25348397 N/A physical interaction ComPPI
G6PD PPAT 25348397 N/A physical interaction ComPPI
RANBP3 PPAT 25348397 N/A physical interaction ComPPI
OTUB1 PPAT 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
TYMS PPAT 25348397 N/A physical interaction ComPPI

Visualization










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