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GENE：PPIE

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PPIE
FullNmae peptidylprolyl isomerase E
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9258
EnsembleID ENSG00000084072
Uniprot Q9UNP9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PPIE cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
PPIE GO:0000398,GO:0000398,GO:0000413,GO:0000413,GO:0003723,GO:0003723,GO:0003729,GO:0003755,GO:0003755,GO:0003755,GO:0005515,GO:0005576,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006355,GO:0006457,GO:0008143,GO:0016018,GO:0016018,GO:0016607,GO:0034774,GO:0043231,GO:0045070,GO:0071007,GO:0071013,GO:1904813

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PPIE hsa:10450 path:hsa03040 Spliceosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 PPIE 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PPIE 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PPIE 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PPIE 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PPIE 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PPIE 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PPIE 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 PPIE 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001012BC PPIE 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D PPIE 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000148B91 PPIE 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016FD1A PPIE 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF PPIE 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 PPIE 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BCAS2 PPIE 25348397 N/A physical interaction ComPPI
SNW1 PPIE 25348397 N/A physical interaction ComPPI
CDC5L PPIE 25348397 N/A physical interaction ComPPI
YJU2 PPIE 25348397 N/A physical interaction ComPPI
SNRPA1 PPIE 25348397 N/A physical interaction ComPPI
SNRPF PPIE 25348397 N/A physical interaction ComPPI
BMI1 PPIE 25348397 N/A physical interaction ComPPI
WDR83 PPIE 25348397 N/A physical interaction ComPPI
SNIP1 PPIE 25348397 N/A physical interaction ComPPI
ACBD3 PPIE 25348397 N/A physical interaction ComPPI
SF3A2 PPIE 24234451 25348397 25599396 N/A cross-linking study,physical interaction ComPPI,IntAct
U2AF2 PPIE 25348397 N/A physical interaction ComPPI
CHTF8 PPIE 25348397 N/A physical interaction ComPPI
HNRNPL PPIE 25348397 N/A physical interaction ComPPI
XAB2 PPIE 14525934 16189514 22365833 24234451 25348397 25416956 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
SF3A1 PPIE 24234451 25348397 25599396 N/A cross-linking study,physical interaction ComPPI,IntAct
H3C1 PPIE 20541251 24234451 25348397 physical association isothermal titration calorimetry,nuclear magnetic resonance ComPPI,IntAct
DVL3 PPIE 25348397 N/A physical interaction ComPPI
PHYHIP PPIE 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MAGOH PPIE 23084401 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PNN PPIE 25348397 N/A physical interaction ComPPI
PLRG1 PPIE 25348397 N/A physical interaction ComPPI
EIF4A3 PPIE 23084401 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRPF19 PPIE 25348397 N/A physical interaction ComPPI
SNRPE PPIE 25348397 N/A physical interaction ComPPI
KMT2A PPIE 11313484 12829790 14525934 17145710 18676843 20541251 24234451 25348397 27898060 physical association two hybrid,experimental interaction detection,molecular sieving,nuclear magnetic resonance,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
RALYL PPIE 25348397 N/A physical interaction ComPPI
PPIE ISY1 25348397 N/A physical interaction ComPPI
PPIE BUD31 25348397 N/A physical interaction ComPPI
PPIE RBM22 25348397 N/A physical interaction ComPPI
PPIE AQR 24234451 25348397 25599396 association,physical association cross-linking study,light scattering,molecular sieving,pull down,physical interaction,ion exchange chromatography ComPPI,IntAct
PPIE CRNKL1 25348397 N/A physical interaction ComPPI
PPIE CWF19L2 25348397 N/A physical interaction ComPPI
PPIE NKAPD1 25348397 N/A physical interaction ComPPI
PPIE TSSC4 25348397 N/A physical interaction ComPPI
PPIE ELAVL2 25348397 N/A physical interaction ComPPI
PPIE DHX8 25348397 N/A physical interaction ComPPI
PPIE ZC3H18 25348397 N/A physical interaction ComPPI
SNRNP40 PPIE 25348397 N/A physical interaction ComPPI
TRMT61B PPIE 25348397 N/A physical interaction ComPPI

Visualization










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