Gene Information gene info

  1. Home

GENE：PSMD6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PSMD6
FullNmae proteasome 26S subunit, non-ATPase 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9564
EnsembleID ENSG00000163636
Uniprot Q15008

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PSMD6 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMD6 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMD6 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
PSMD6 GO:0000502,GO:0000502,GO:0005515,GO:0005576,GO:0005654,GO:0005829,GO:0005838,GO:0022624,GO:0034774,GO:0043161,GO:0043161,GO:1904813

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PSMD6 hsa:9861 path:hsa03050 Proteasome - Homo sapiens (human)
PSMD6 hsa:9861 path:hsa05010 Alzheimer disease - Homo sapiens (human)
PSMD6 hsa:9861 path:hsa05012 Parkinson disease - Homo sapiens (human)
PSMD6 hsa:9861 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
PSMD6 hsa:9861 path:hsa05016 Huntington disease - Homo sapiens (human)
PSMD6 hsa:9861 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
PSMD6 hsa:9861 path:hsa05020 Prion disease - Homo sapiens (human)
PSMD6 hsa:9861 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
PSMD6 hsa:9861 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PSMD6 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PSMD6 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PSMD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PSMD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PSMD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PSMD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 PSMD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PSMD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
BRCA2 PSMD6 17563742 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 PSMD6 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 PSMD6 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000BE495 PSMD6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC PSMD6 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PSMA4 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 PSMA4 25361965 interaction type N/A PTMCode2
PSMD6 PSMC3 25361965 interaction type N/A PTMCode2
PSMC3 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 RPS27A 25361965 interaction type N/A PTMCode2
RPS27A PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 CDC20 25361965 interaction type N/A PTMCode2
CDC20 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 PSMA1 25361965 interaction type N/A PTMCode2
PSMA1 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 PSMB10 25361965 interaction type N/A PTMCode2
PSMB10 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 CDC23 25361965 interaction type N/A PTMCode2
CDC23 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 FZR1 25361965 interaction type N/A PTMCode2
FZR1 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 PSMC6 25361965 interaction type N/A PTMCode2
PSMC6 PSMD6 25361965 interaction type N/A PTMCode2
USP14 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 USP14 25361965 interaction type N/A PTMCode2
PSMC1 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 PSMC1 25361965 interaction type N/A PTMCode2
PSMA5 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 PSMA5 25361965 interaction type N/A PTMCode2
PSMD11 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 PSMD11 25361965 interaction type N/A PTMCode2
PSMD5 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 PSMD5 25361965 interaction type N/A PTMCode2
PSMD7 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 PSMD7 25361965 interaction type N/A PTMCode2
PSMA3 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 PSMA3 25361965 interaction type N/A PTMCode2
PSMD10 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 PSMD10 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
USP20 PSMD6 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF1B PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HSPA8 PSMD6 24234451 25348397 29568061 association pull down ComPPI,IntAct
PSMB10 PSMD6 25348397 N/A physical interaction ComPPI
PSMC3 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMC6 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD14 PSMD6 17353931 19615732 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TP53BP1 PSMD6 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
TRAF6 PSMD6 14525934 14743216 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
PSMD7 PSMD6 17353931 19615732 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DKK1 PSMD6 25348397 N/A physical interaction ComPPI
LMNA PSMD6 24234451 25348397 29568061 association pull down ComPPI,IntAct
NUBP2 PSMD6 25348397 N/A physical interaction ComPPI
KEAP1 PSMD6 25348397 N/A physical interaction ComPPI
PSMB2 PSMD6 25348397 N/A physical interaction ComPPI
ABRAXAS2 PSMD6 19214193 24234451 25348397 association biochemical ComPPI,IntAct
JUN PSMD6 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
PSMA3 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD11 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PEX19 PSMD6 25348397 N/A physical interaction ComPPI
UBC PSMD6 25348397 N/A physical interaction ComPPI
DLD PSMD6 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NTRK1 PSMD6 25348397 N/A physical interaction ComPPI
AXIN1 PSMD6 22682247 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PTPN2 PSMD6 25348397 N/A physical interaction ComPPI
RPS3A PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMA1 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA6 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA5 PSMD6 25348397 N/A physical interaction ComPPI
PSMB9 PSMD6 25348397 N/A physical interaction ComPPI
HNRNPU PSMD6 25348397 N/A physical interaction ComPPI
RMND5B PSMD6 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
GORASP2 PSMD6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK6 PSMD6 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
PSMD8 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB8 PSMD6 25348397 N/A physical interaction ComPPI
PSMD1 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TNIK PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
UBAC1 PSMD6 25348397 N/A physical interaction ComPPI
BRCA2 PSMD6 25348397 N/A physical interaction ComPPI
CCNA1 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMC5 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HUWE1 PSMD6 25348397 N/A physical interaction ComPPI
RAD23A PSMD6 25348397 N/A physical interaction ComPPI
ATP1B1 PSMD6 25348397 N/A physical interaction ComPPI
PSMC4 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MED23 PSMD6 25348397 N/A physical interaction ComPPI
YAP1 PSMD6 25348397 N/A physical interaction ComPPI
HSPB1 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NOS2 PSMD6 25348397 N/A physical interaction ComPPI
PSMD2 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RAD23B PSMD6 16424905 24234451 25348397 physical association pull down ComPPI,IntAct
PRKN PSMD6 25348397 N/A physical interaction ComPPI
PSMD10 PSMD6 17353931 19490896 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL7 PSMD6 25348397 N/A physical interaction ComPPI
HDAC5 PSMD6 25348397 N/A physical interaction ComPPI
PSMD4 PSMD6 16990800 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMM13 PSMD6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP8 PSMD6 25348397 N/A physical interaction ComPPI
SGK1 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
BUB1B PSMD6 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SEM1 PSMD6 25348397 N/A physical interaction ComPPI
PSMB5 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SSRP1 PSMD6 25348397 N/A physical interaction ComPPI
CASP4 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSME1 PSMD6 25348397 N/A physical interaction ComPPI
PSME2 PSMD6 25348397 N/A physical interaction ComPPI
UBQLN1 PSMD6 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PSMC1 PSMD6 17353931 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AMFR PSMD6 25348397 N/A physical interaction ComPPI
BRCA1 PSMD6 25348397 N/A physical interaction ComPPI
MLH1 PSMD6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MCFD2 PSMD6 25348397 N/A physical interaction ComPPI
PSMB4 PSMD6 25348397 N/A physical interaction ComPPI
PSMB1 PSMD6 25348397 N/A physical interaction ComPPI
PSMB3 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB7 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA7 PSMD6 25348397 N/A physical interaction ComPPI
PSMA4 PSMD6 25348397 N/A physical interaction ComPPI
ELF3 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RNF11 PSMD6 25348397 N/A physical interaction ComPPI
PSMD5 PSMD6 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAB1 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PPM1D PSMD6 24234451 25348397 28330616 association pull down ComPPI,IntAct
BAG2 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
IKBKE PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CEP250 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
UBE3C PSMD6 25348397 N/A physical interaction ComPPI
VPS29 PSMD6 25348397 N/A physical interaction ComPPI
UCHL5 PSMD6 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
L3MBTL1 PSMD6 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
ZFAND5 PSMD6 14525934 16424905 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
HSD17B10 PSMD6 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MCC PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ADRM1 PSMD6 24234451 24811749 25348397 association physical interaction,blue native page ComPPI,IntAct
PSMD13 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD12 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PCID2 PSMD6 25348397 N/A physical interaction ComPPI
PSMD9 PSMD6 25348397 N/A physical interaction ComPPI
UBLCP1 PSMD6 25348397 N/A physical interaction ComPPI
ZFAND2B PSMD6 25348397 N/A physical interaction ComPPI
PSMC2 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD6 PSMD3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD6 PAAF1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD6 PSMA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD6 TELO2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD6 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD6 SLX1A 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD6 PCK1 25348397 N/A physical interaction ComPPI
PSMD6 SEM1 25348397 N/A physical interaction ComPPI
PSMD6 FBXO25 25348397 N/A physical interaction ComPPI
PSMD6 PSMB6 25348397 N/A physical interaction ComPPI
PSMD6 PSMA8 25348397 N/A physical interaction ComPPI
PSMD6 PLS3 25348397 N/A physical interaction ComPPI
PSMD6 TP53 25348397 N/A physical interaction ComPPI
PSMD6 CCDC74B 25348397 N/A physical interaction ComPPI
PSMD6 CCDC92 25348397 N/A physical interaction ComPPI
PSMD6 AMBRA1 25348397 N/A physical interaction ComPPI
PSMD6 AHCYL1 25348397 N/A physical interaction ComPPI
PSMD6 ATP1B3 25348397 N/A physical interaction ComPPI
PSMD6 SYAP1 25348397 N/A physical interaction ComPPI
PSMD6 KDELR1 25348397 N/A physical interaction ComPPI
PSMD6 CCDC102B 25348397 N/A physical interaction ComPPI
PSMD6 ATG9A 25348397 N/A physical interaction ComPPI
PSMD6 FAM107A 25348397 N/A physical interaction ComPPI
PSMD6 TMEM33 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD6 MTHFD1L 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD6 TAGLN2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD6 ATAD3A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD6 HLA-C 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD6 ARMC6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD6 TXNL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD6 ATP5F1D 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD6 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD6 LRRK2 24234451 24725412 25348397 association tandem affinity purification ComPPI,IntAct
PSMD6 CMTM7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PSMD6 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct

Visualization










  Return