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GENE：PTCD3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTCD3
FullNmae pentatricopeptide repeat domain 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24717
EnsembleID ENSG00000132300
Uniprot Q96EY7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTCD3 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
PTCD3 GO:0003723,GO:0005515,GO:0005654,GO:0005739,GO:0005739,GO:0005743,GO:0005743,GO:0005763,GO:0005829,GO:0005886,GO:0006417,GO:0019843,GO:0019843,GO:0032543,GO:0032543,GO:0032543,GO:0043024,GO:0043024

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SUZ12 PTCD3 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 PTCD3 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 PTCD3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PTCD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PTCD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PTCD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PTCD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 PTCD3 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000CF1D2 PTCD3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EED18 PTCD3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001067D1 PTCD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 PTCD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 PTCD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC PTCD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 PTCD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E PTCD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 PTCD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD PTCD3 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000023F8DA PTCD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 PTCD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EC1BE PTCD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 PTCD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA PTCD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 PTCD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 PTCD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC PTCD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C PTCD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000048D44E PTCD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 PTCD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001123BD PTCD3 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000007F792 PTCD3 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000B0E50 PTCD3 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00005E1A16 PTCD3 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ATF4 PTCD3 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
LCA5 PTCD3 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ZBTB48 PTCD3 25348397 N/A physical interaction ComPPI
ZNF707 PTCD3 25348397 N/A physical interaction ComPPI
NOL12 PTCD3 25348397 N/A physical interaction ComPPI
BMI1 PTCD3 25348397 N/A physical interaction ComPPI
NIFK PTCD3 25348397 N/A physical interaction ComPPI
RRS1 PTCD3 25348397 N/A physical interaction ComPPI
SNRNP70 PTCD3 25348397 N/A physical interaction ComPPI
JUN PTCD3 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
CUL3 PTCD3 25348397 N/A physical interaction ComPPI
DAP3 PTCD3 25348397 N/A physical interaction ComPPI
HGS PTCD3 25348397 N/A physical interaction ComPPI
NTRK1 PTCD3 25348397 N/A physical interaction ComPPI
YBX1 PTCD3 22118625 23986595 24234451 25348397 25497084 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,tandem affinity purification ComPPI,IntAct
PDGFB PTCD3 25348397 N/A physical interaction ComPPI
E4F1 PTCD3 25348397 N/A physical interaction ComPPI
C1QBP PTCD3 25348397 N/A physical interaction ComPPI
CFTR PTCD3 25348397 N/A physical interaction ComPPI
RPS6 PTCD3 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
SYNCRIP PTCD3 25348397 N/A physical interaction ComPPI
RNF2 PTCD3 25348397 N/A physical interaction ComPPI
MED23 PTCD3 25348397 N/A physical interaction ComPPI
SSX2IP PTCD3 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLP2 PTCD3 25348397 N/A physical interaction ComPPI
PRKN PTCD3 25348397 N/A physical interaction ComPPI
H3C1 PTCD3 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
CAND1 PTCD3 25348397 N/A physical interaction ComPPI
PDK1 PTCD3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RFXANK PTCD3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TBPL1 PTCD3 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ACIN1 PTCD3 25348397 N/A physical interaction ComPPI
BIRC7 PTCD3 25348397 N/A physical interaction ComPPI
H2AX PTCD3 25348397 N/A physical interaction ComPPI
ESR1 PTCD3 21182203 24234451 25348397 association pull down ComPPI,IntAct
ESR2 PTCD3 21182203 24234451 25348397 25604459 association affinity chromatography technology,cosedimentation through density gradient,physical interaction,tandem affinity purification ComPPI,IntAct
RPL6 PTCD3 25348397 N/A physical interaction ComPPI
RPL13 PTCD3 25348397 N/A physical interaction ComPPI
RBM42 PTCD3 25348397 N/A physical interaction ComPPI
AURKAIP1 PTCD3 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TRA2A PTCD3 25348397 N/A physical interaction ComPPI
FBXW11 PTCD3 25348397 N/A physical interaction ComPPI
LNX2 PTCD3 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CEP250 PTCD3 25348397 N/A physical interaction ComPPI
LUC7L PTCD3 25348397 N/A physical interaction ComPPI
LUC7L2 PTCD3 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
IFITM2 PTCD3 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
AGO2 PTCD3 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
AGO1 PTCD3 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SUZ12 PTCD3 25348397 N/A physical interaction ComPPI
HSPD1 PTCD3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPS34 PTCD3 25348397 N/A physical interaction ComPPI
HNRNPA1 PTCD3 25348397 N/A physical interaction ComPPI
PTCD3 MRPL58 20186120 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTCD3 SIRT7 25348397 N/A physical interaction ComPPI
PTCD3 MRPS15 19427859 24234451 25348397 27898060 physical association physical interaction,tandem affinity purification ComPPI,IntAct,OmniPath
PTCD3 MPV17 25348397 N/A physical interaction ComPPI
PTCD3 GRSF1 25348397 N/A physical interaction ComPPI
PTCD3 STAU1 25348397 N/A physical interaction ComPPI
PTCD3 TP53 25348397 N/A physical interaction ComPPI
PTCD3 NSA2 25348397 N/A physical interaction ComPPI
PTCD3 MRPS2 25348397 N/A physical interaction ComPPI
PTCD3 ZC3H3 25348397 N/A physical interaction ComPPI
PTCD3 RPS8 25348397 N/A physical interaction ComPPI
PTCD3 TRMT10B 25348397 N/A physical interaction ComPPI
PTCD3 ZBTB38 25348397 N/A physical interaction ComPPI
PTCD3 MRPS31 25348397 N/A physical interaction ComPPI
PTCD3 MRPS5 25348397 N/A physical interaction ComPPI
PTCD3 MRPS11 25348397 N/A physical interaction ComPPI
PTCD3 MRPS18B 25348397 N/A physical interaction ComPPI
PTCD3 MRPS28 25348397 N/A physical interaction ComPPI
PTCD3 MRPS35 25348397 N/A physical interaction ComPPI
PTCD3 MRPS9 25348397 N/A physical interaction ComPPI
PTCD3 MRPS22 25348397 N/A physical interaction ComPPI
PTCD3 SPICE1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTCD3 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PTCD3 NANOGP8 25348397 N/A physical interaction ComPPI
PTCD3 NANOG 25348397 N/A physical interaction ComPPI
PTCD3 POU5F1 25348397 N/A physical interaction ComPPI
PTCD3 ZNF746 25348397 N/A physical interaction ComPPI
PTCD3 TBC1D2B 25348397 N/A physical interaction ComPPI
PTCD3 MRPS27 25348397 N/A physical interaction ComPPI
PTCD3 ZFC3H1 25348397 N/A physical interaction ComPPI
PTCD3 CCDC59 25348397 N/A physical interaction ComPPI
PTCD3 FGF8 25348397 N/A physical interaction ComPPI
PTCD3 ZNF2 25348397 N/A physical interaction ComPPI
PTCD3 ZNF331 25348397 N/A physical interaction ComPPI
PTCD3 RBM38 25348397 N/A physical interaction ComPPI
PTCD3 LRRK2 24234451 24725412 25348397 association tandem affinity purification ComPPI,IntAct
PTCD3 SIRT4 24234451 25348397 25525879 association anti tag coimmunoprecipitation ComPPI,IntAct
PTCD3 AIFM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PTCD3 COX14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PTCD3 FBL 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
PTCD3 SCO1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CD55 PTCD3 25348397 N/A physical interaction ComPPI
COX4I1 PTCD3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MGST3 PTCD3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRMT61B PTCD3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPS23 PTCD3 25348397 N/A physical interaction ComPPI
FAM3C PTCD3 25348397 N/A physical interaction ComPPI
MKI67 PTCD3 24234451 26949251 association anti tag coimmunoprecipitation IntAct
L1TD1 PTCD3 24234451 25702638 association anti bait coimmunoprecipitation IntAct

Source Target Pmid Interactiontype Methods Database
URS00009BF711 PTCD3 27087310 direct interaction,inhibition N/A NPInter

Visualization










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