GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
QRSL1
FullNmae
glutaminyl-tRNA amidotransferase subunit QRSL1
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:21020
EnsembleID
ENSG00000130348
Uniprot
Q9H0R6
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
QRSL1
immunogenic
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
QRSL1
cuproptosis
36010978
Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1.
Cuproptosis-related genes
Go Annotation:
GeneSymbol
Go id
QRSL1
GO:0005515,GO:0005524,GO:0005739,GO:0005739,GO:0030956,GO:0030956,GO:0030956,GO:0031647,GO:0032543,GO:0032543,GO:0050567,GO:0050567,GO:0070681,GO:0070681
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
ETS1
QRSL1
20019798
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
YBX1
QRSL1
19151767
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
FOXP3
QRSL1
20554955
trascriptional regulation,stimulation
chromatin immunoprecipitation array
TFlink
PRDM14
QRSL1
18971253
20953172
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
SMARCA4
QRSL1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
EGR1
QRSL1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOXA1
QRSL1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
GATA2
QRSL1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
RUNX1
QRSL1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
SPI1
QRSL1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS0000324096
QRSL1
18668040
25416803
mrna cleavage,inhibition
experimental interaction detection
TarBase
URS00004E008F
QRSL1
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS000012A1DD
QRSL1
22499991
25416803
mrna cleavage,inhibition
western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay
TarBase
URS0000170D8B
QRSL1
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000044FD7
QRSL1
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS00003AA845
QRSL1
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00002C0FCB
QRSL1
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000016D2D4
QRSL1
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00001FC26E
QRSL1
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000411752
QRSL1
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000005CE28
QRSL1
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000EEF5F
QRSL1
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000753AD
QRSL1
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000041E780
QRSL1
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
XRCC6
QRSL1
21900206
24234451
25348397
physical association
two hybrid,physical interaction
ComPPI,IntAct
MICAL1
QRSL1
21900206
24234451
25348397
physical association
two hybrid
ComPPI,IntAct
PDK1
QRSL1
24234451
25348397
29568061
association
proximity-dependent biotin identification
ComPPI,IntAct
CLPP
QRSL1
24234451
25348397
26058080
association
proximity-dependent biotin identification
ComPPI,IntAct
PPBP
QRSL1
21900206
24234451
25348397
physical association
two hybrid
ComPPI,IntAct
HSPD1
QRSL1
24234451
25348397
29568061
association
proximity-dependent biotin identification
ComPPI,IntAct
KRT8
QRSL1
21900206
24234451
25348397
physical association
two hybrid,physical interaction
ComPPI,IntAct
TRMT61B
QRSL1
24234451
25348397
29568061
association
proximity-dependent biotin identification
ComPPI,IntAct
Visualization