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GENE：RAD23B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RAD23B
FullNmae RAD23 homolog B, nucleotide excision repair protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9813
EnsembleID ENSG00000119318
Uniprot P54727

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RAD23B cuproptosis 36341328 Further, differentially expressed genes with prognostic significance were used to construct a cuproptosis-related gene signature (PGK1, SLC52A2, SEC14L2, RAD23B, SLC16A6, CCL5, and MAL2) and scoring system. cuproptosis-related gene signature

Go Annotation:

GeneSymbol Go id
RAD23B GO:0000502,GO:0000978,GO:0003684,GO:0003697,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005654,GO:0005829,GO:0005829,GO:0005829,GO:0006289,GO:0007283,GO:0031593,GO:0031593,GO:0032434,GO:0043130,GO:0043161,GO:0061629,GO:0070628,GO:0071942,GO:0098761,GO:0140612

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RAD23B hsa:5887 path:hsa03420 Nucleotide excision repair - Homo sapiens (human)
RAD23B hsa:5887 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR RAD23B 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 RAD23B 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RAD23B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 RAD23B 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A RAD23B 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
YBX1 RAD23B 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 RAD23B 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RAD23B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RAD23B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RAD23B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RAD23B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RAD23B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RAD23B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 RAD23B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RAD23B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RAD23B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RAD23B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR RAD23B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 RAD23B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000508C13 RAD23B 19141645 \N rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000508C13 RAD23B 18927107 19141645 22012620 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS0000065D58 RAD23B 18668040 22473208 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS0000338542 RAD23B 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000FC8EB RAD23B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000600E6 RAD23B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000F4AC3 RAD23B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000039E1E1 RAD23B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000535FDD RAD23B 21572407 24823364 25416803 mrna cleavage,inhibition western blot,clip,miRNA interference luciferase reporter assay TarBase
URS0000171CD1 RAD23B 20371350 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C RAD23B 20371350 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D RAD23B 20371350 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 RAD23B 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A RAD23B 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F RAD23B 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 RAD23B 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 RAD23B 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000157F5 RAD23B 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000016FF9C RAD23B 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D RAD23B 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D RAD23B 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000519450 RAD23B 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000058BB84 RAD23B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002AB575 RAD23B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075D1FC RAD23B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000CF1D2 RAD23B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000166778 RAD23B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002A79D1 RAD23B 21572407 25416803 mrna cleavage,inhibition clip,clip TarBase
URS000006372A RAD23B 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS0000077AED RAD23B 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 RAD23B 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000002569A RAD23B 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF RAD23B 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 RAD23B 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC4BD RAD23B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 RAD23B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000007340 RAD23B 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PSMD1 RAD23B 25361965 interaction type N/A PTMCode2
RAD23B PSMD1 25361965 interaction type N/A PTMCode2
UBA2 RAD23B 25361965 interaction type N/A PTMCode2
RAD23B UBA2 25361965 interaction type N/A PTMCode2
XPC RAD23B 25361965 interaction type N/A PTMCode2
RAD23B XPC 25361965 interaction type N/A PTMCode2
RAD23B RAD52 25361965 interaction type N/A PTMCode2
RAD52 RAD23B 25361965 interaction type N/A PTMCode2
RAD23B XPA 25361965 interaction type N/A PTMCode2
XPA RAD23B 25361965 interaction type N/A PTMCode2
RAD23B TDG 25361965 interaction type N/A PTMCode2
TDG RAD23B 25361965 interaction type N/A PTMCode2
USP5 RAD23B 25361965 interaction type N/A PTMCode2
RAD23B USP5 25361965 interaction type N/A PTMCode2
NGLY1 RAD23B 25361965 interaction type N/A PTMCode2
RAD23B NGLY1 25361965 interaction type N/A PTMCode2
RPS27A RAD23B 25361965 interaction type N/A PTMCode2
RAD23B RPS27A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CBSL RAD23B 25348397 N/A physical interaction ComPPI
MAD2L2 RAD23B 25348397 N/A physical interaction ComPPI
VIM RAD23B 16712842 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
PNMA5 RAD23B 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PSMC6 RAD23B 20890303 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
SNRPF RAD23B 25348397 N/A physical interaction ComPPI
PSMD14 RAD23B 25348397 N/A physical interaction ComPPI
NUBP2 RAD23B 25348397 N/A physical interaction ComPPI
CALM1 RAD23B 25348397 N/A physical interaction ComPPI
ERCC3 RAD23B 10734143 24234451 25348397 physical association pull down ComPPI,IntAct
H2BC4 RAD23B 25348397 N/A physical interaction ComPPI
PSMB2 RAD23B 25348397 N/A physical interaction ComPPI
CETN2 RAD23B 21962512 24234451 25348397 26638075 association affinity chromatography technology,chromatography technology,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
UBL7 RAD23B 25348397 N/A physical interaction ComPPI
RBM8A RAD23B 25348397 N/A physical interaction ComPPI
TACC3 RAD23B 25348397 N/A physical interaction ComPPI
ZYX RAD23B 25348397 N/A physical interaction ComPPI
TDG RAD23B 12505994 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
HIF1A RAD23B 25348397 N/A physical interaction ComPPI
PSMA3 RAD23B 25348397 N/A physical interaction ComPPI
GTF2I RAD23B 25348397 N/A physical interaction ComPPI
SPART RAD23B 25348397 N/A physical interaction ComPPI
PDIA3 RAD23B 25348397 N/A physical interaction ComPPI
GTF2H1 RAD23B 25348397 N/A physical interaction ComPPI
UBB RAD23B 14525934 16712842 17662948 24234451 25348397 association,physical association experimental interaction detection,pull down,two hybrid array,two hybrid prey pooling approach ComPPI,HPRD,IntAct
UBC RAD23B 12832454 16196087 16712842 19182904 20059542 22871113 23314748 23649778 24234451 25348397 25752573 27898060 physical association pull down,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct,OmniPath
UBE2N RAD23B 25348397 N/A physical interaction ComPPI
NTRK1 RAD23B 25348397 N/A physical interaction ComPPI
RPA1 RAD23B 25348397 N/A physical interaction ComPPI
PLK1 RAD23B 21887822 24234451 25348397 phosphorylation reaction,colocalization protein kinase assay,confocal microscopy ComPPI,IntAct
EEF1A1 RAD23B 16712842 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
HMGB1 RAD23B 25348397 N/A physical interaction ComPPI
MAPK6 RAD23B 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
PDLIM5 RAD23B 25348397 N/A physical interaction ComPPI
EWSR1 RAD23B 25348397 N/A physical interaction ComPPI
PSMD1 RAD23B 16712842 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
PKM RAD23B 25348397 N/A physical interaction ComPPI
UBA6 RAD23B 25348397 N/A physical interaction ComPPI
PSMC5 RAD23B 10488153 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
UBQLN2 RAD23B 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RAD23A RAD23B 16105547 25348397 27898060 8692695 N/A physical interaction ComPPI,OmniPath
UBA2 RAD23B 14525934 17662948 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SUMO3 RAD23B 25348397 N/A physical interaction ComPPI
SPR RAD23B 25348397 N/A physical interaction ComPPI
SPTA1 RAD23B 25348397 N/A physical interaction ComPPI
SOX2 RAD23B 25348397 N/A physical interaction ComPPI
PSMC4 RAD23B 25348397 N/A physical interaction ComPPI
DRAP1 RAD23B 25348397 N/A physical interaction ComPPI
STAT6 RAD23B 25348397 N/A physical interaction ComPPI
XPC RAD23B 10488153 11259578 11279143 14525934 21962512 24234451 25348397 association,physical association affinity chromatography technology,two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
HDAC6 RAD23B 25348397 N/A physical interaction ComPPI
UBQLN4 RAD23B 25348397 N/A physical interaction ComPPI
TAX1BP1 RAD23B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PSMD2 RAD23B 25348397 N/A physical interaction ComPPI
ATXN3 RAD23B 10915768 14525934 16713569 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid ComPPI,HPRD,IntAct
RAD23B PSMD4 10488153 14525934 16990800 20059542 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,cosedimentation through density gradient,experimental interaction detection,pull down,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
RAD23B MPG 10854423 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RAD23B NGLY1 11259433 11562482 14525934 15351714 15358861 15964983 16249333 16401726 22119785 22575648 24234451 25348397 25416956 26344197 27898060 physical association experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct,OmniPath
RAD23B ZFAND5 14525934 16424905 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,in vitro,two hybrid ComPPI,HPRD,IntAct
RAD23B PAX3 25348397 N/A physical interaction ComPPI
RAD23B OTUD1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAD23B UCHL5 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAD23B UBE3A 25348397 N/A physical interaction ComPPI
RAD23B RNF185 25348397 N/A physical interaction ComPPI
RAD23B DEAF1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RAD23B DBI 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RAD23B ELAVL1 25348397 N/A physical interaction ComPPI
RAD23B PSMA2 25348397 N/A physical interaction ComPPI
RAD23B UBA1 25348397 N/A physical interaction ComPPI
RAD23B USP5 16712842 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
RAD23B EEF1A1P5 25348397 N/A physical interaction ComPPI
RAD23B BRCA1 16712842 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
RAD23B PSMC2 16712842 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
RAD23B PSMD13 25348397 N/A physical interaction ComPPI
RAD23B PSMB7 25348397 N/A physical interaction ComPPI
RAD23B UBE2V2 25348397 N/A physical interaction ComPPI
RAD23B STUB1 25348397 N/A physical interaction ComPPI
RAD23B UBQLN1 25348397 N/A physical interaction ComPPI
RAD23B LCP1 25348397 N/A physical interaction ComPPI
RAD23B PPIL3 25348397 N/A physical interaction ComPPI
RAD23B IGBP1 25348397 N/A physical interaction ComPPI
RAD23B RPS21 25348397 N/A physical interaction ComPPI
RAD23B UFM1 25348397 N/A physical interaction ComPPI
RAD23B PRDX5 25348397 N/A physical interaction ComPPI
RAD23B UBXN7 25348397 N/A physical interaction ComPPI
RAD23B PPIA 25348397 N/A physical interaction ComPPI
RAD23B NANS 25348397 N/A physical interaction ComPPI
RAD23B POU5F1 25348397 N/A physical interaction ComPPI
RAD23B MLH1 20706999 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RAD23B PRKN 25348397 N/A physical interaction ComPPI
RAD23B ADSL 25348397 N/A physical interaction ComPPI
RAD23B PDE12 25348397 N/A physical interaction ComPPI
RAD23B CBS 25348397 N/A physical interaction ComPPI
RAD23B NPLOC4 25348397 N/A physical interaction ComPPI
RAD23B PLIN3 25348397 N/A physical interaction ComPPI
RAD23B XPNPEP1 25348397 N/A physical interaction ComPPI
RAD23B SEM1 25348397 N/A physical interaction ComPPI
RAD23B PUF60 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RAD23B COMMD4 25348397 N/A physical interaction ComPPI
RAD23B CORO1B 25348397 N/A physical interaction ComPPI
RAD23B CORO1C 25348397 N/A physical interaction ComPPI
RAD23B DNAAF5 25348397 N/A physical interaction ComPPI
RAD23B G6PD 25348397 N/A physical interaction ComPPI
RAD23B MYO6 25348397 N/A physical interaction ComPPI
RAD23B ABAT 25348397 N/A physical interaction ComPPI
RAD23B AHSA1 25348397 N/A physical interaction ComPPI
RAD23B HMGCS1 25348397 N/A physical interaction ComPPI
RAD23B NMD3 25348397 N/A physical interaction ComPPI
RAD23B PHGDH 25348397 N/A physical interaction ComPPI
RAD23B PSMC1 25348397 N/A physical interaction ComPPI
RAD23B SEC24B 25348397 N/A physical interaction ComPPI
RAD23B H2BC11 25348397 N/A physical interaction ComPPI
RAD23B MED20 25348397 N/A physical interaction ComPPI
RAD23B NANOGP8 25348397 N/A physical interaction ComPPI
RAD23B NANOG 25348397 N/A physical interaction ComPPI
RAD23B CDKN3 25348397 N/A physical interaction ComPPI
RAD23B USP25 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RAD23B UBE4B 15121879 15652483 16401726 16427015 19898607 20427284 21807993 25348397 27898060 N/A physical interaction ComPPI,OmniPath
RAD23B KCTD10 25348397 N/A physical interaction ComPPI
RAD23B KCTD3 25348397 N/A physical interaction ComPPI
RAD23B BTBD9 25348397 N/A physical interaction ComPPI
RAD23B DDI2 25348397 N/A physical interaction ComPPI
RAD23B TRIM25 25348397 N/A physical interaction ComPPI
RAD23B PAQR3 25348397 N/A physical interaction ComPPI
RAD23B PSMD6 16424905 24234451 25348397 physical association pull down ComPPI,IntAct
RAD23B UBA3 16712842 24234451 25348397 physical association pull down ComPPI,IntAct
RAD23B ETS1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RAD23B PSMD12 20890303 24234451 25348397 physical association pull down ComPPI,IntAct
RAD23B HIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RAD23B MKRN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RAD23B RSC1A1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RAD23B POU6F2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
H3C1 RAD23B 25348397 N/A physical interaction ComPPI
SEM1 RAD23B 24234451 24811749 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUCB1 RAD23B 25348397 N/A physical interaction ComPPI
EIF4A3 RAD23B 25348397 N/A physical interaction ComPPI
ADRM1 RAD23B 14525934 18497817 20059542 24234451 25348397 N/A experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
ECPAS RAD23B 25348397 N/A physical interaction ComPPI
HSCB RAD23B 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
RPN1 RAD23B 11595789 12198498 15121879 16401726 17082762 18511945 20059542 21627799 22318722 27898060 N/A N/A OmniPath
RAD23B DDI1 11700052 11805121 16405905 27898060 N/A N/A OmniPath

Visualization










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