Gene Information gene info

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GENE：RPAIN

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RPAIN
FullNmae RPA interacting protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28641
EnsembleID ENSG00000129197
Uniprot Q86UA6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RPAIN immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RPAIN cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
RPAIN GO:0001650,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0006606,GO:0006606,GO:0016605,GO:0046872

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F1 RPAIN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RPAIN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 RPAIN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 RPAIN 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000041FA2C RPAIN 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D RPAIN 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000008F0CF RPAIN 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
RPA1 RPAIN 25348397 N/A physical interaction ComPPI
HNRNPL RPAIN 25348397 N/A physical interaction ComPPI
RPA2 RPAIN 25348397 N/A physical interaction ComPPI
CYP17A1 RPAIN 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CLNK RPAIN 25348397 N/A physical interaction ComPPI
CDCA5 RPAIN 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TNS4 RPAIN 25348397 N/A physical interaction ComPPI
RPAIN ADH6 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct

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