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GENE：RPL27

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RPL27
FullNmae ribosomal protein L27
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10328
EnsembleID ENSG00000131469
Uniprot P61353

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RPL27 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
RPL27 GO:0002181,GO:0002181,GO:0003723,GO:0003735,GO:0003735,GO:0003735,GO:0003735,GO:0005515,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0005840,GO:0005925,GO:0006364,GO:0006412,GO:0016020,GO:0022625,GO:0022625,GO:0022625,GO:0022625,GO:0022626,GO:0045202,GO:0070062,GO:0098556,GO:1904044,GO:1990904

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RPL27 hsa:6155 path:hsa03010 Ribosome - Homo sapiens (human)
RPL27 hsa:6155 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 RPL27 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 RPL27 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RPL27 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC RPL27 12747840 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 RPL27 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 RPL27 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RPL27 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RPL27 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR RPL27 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000008F0CF RPL27 20489155 25416803 mrna cleavage,inhibition array technology TarBase
URS00001012BC RPL27 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000013DD8 RPL27 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D RPL27 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD RPL27 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 RPL27 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 RPL27 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
RPS16 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPS16 25361965 interaction type N/A PTMCode2
RPL27 RPL35 25361965 interaction type N/A PTMCode2
RPL35 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL8 25361965 interaction type N/A PTMCode2
RPL8 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL3L 25361965 interaction type N/A PTMCode2
RPL3L RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPS11 25361965 interaction type N/A PTMCode2
RPS11 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL37 25361965 interaction type N/A PTMCode2
RPL37 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL30 25361965 interaction type N/A PTMCode2
RPL30 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPS9 25361965 interaction type N/A PTMCode2
RPS9 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL13 25361965 interaction type N/A PTMCode2
RPL13 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL15 25361965 interaction type N/A PTMCode2
RPL15 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL38 25361965 interaction type N/A PTMCode2
RPL38 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPS14 25361965 interaction type N/A PTMCode2
RPS14 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL4 25361965 interaction type N/A PTMCode2
RPL4 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPS15A 25361965 interaction type N/A PTMCode2
RPS15A RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPLP2 25361965 interaction type N/A PTMCode2
RPLP2 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPLP0 25361965 interaction type N/A PTMCode2
RPLP0 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPS7 25361965 interaction type N/A PTMCode2
RPS7 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL7 25361965 interaction type N/A PTMCode2
RPL7 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL14 25361965 interaction type N/A PTMCode2
RPL14 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL3 25361965 interaction type N/A PTMCode2
RPL3 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL9 25361965 interaction type N/A PTMCode2
RPL9 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPLP1 25361965 interaction type N/A PTMCode2
RPLP1 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPS3A 25361965 interaction type N/A PTMCode2
RPS3A RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL22 25361965 interaction type N/A PTMCode2
RPL22 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL12 25361965 interaction type N/A PTMCode2
RPL12 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL5 25361965 interaction type N/A PTMCode2
RPL5 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPS4X 25361965 interaction type N/A PTMCode2
RPS4X RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL10A 25361965 interaction type N/A PTMCode2
RPL10A RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL11 25361965 interaction type N/A PTMCode2
RPL11 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPS6 25361965 interaction type N/A PTMCode2
RPS6 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL24 25361965 interaction type N/A PTMCode2
RPL24 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL23 25361965 interaction type N/A PTMCode2
RPL23 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL34 25361965 interaction type N/A PTMCode2
RPL34 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPS8 25361965 interaction type N/A PTMCode2
RPS8 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL32 25361965 interaction type N/A PTMCode2
RPL32 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL31 25361965 interaction type N/A PTMCode2
RPL31 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL35A 25361965 interaction type N/A PTMCode2
RPL35A RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL36A 25361965 interaction type N/A PTMCode2
RPL36A RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL37A 25361965 interaction type N/A PTMCode2
RPL37A RPL27 25361965 interaction type N/A PTMCode2
RPS5 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPS5 25361965 interaction type N/A PTMCode2
RPL19 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL19 25361965 interaction type N/A PTMCode2
RPL6 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL6 25361965 interaction type N/A PTMCode2
RPL36 RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL36 25361965 interaction type N/A PTMCode2
RPL18A RPL27 25361965 interaction type N/A PTMCode2
RPL27 RPL18A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CUL5 RPL27 25348397 N/A physical interaction ComPPI
RPL9 RPL27 25348397 N/A physical interaction ComPPI
RPS7 RPL27 25348397 N/A physical interaction ComPPI
PPP1CC RPL27 20926688 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down ComPPI,IntAct
NPM1 RPL27 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL37A RPL27 25348397 N/A physical interaction ComPPI
UBL4A RPL27 25348397 N/A physical interaction ComPPI
GABARAPL2 RPL27 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL11 RPL27 25348397 N/A physical interaction ComPPI
RPS15 RPL27 25348397 N/A physical interaction ComPPI
RPS26 RPL27 25348397 N/A physical interaction ComPPI
KEAP1 RPL27 25348397 N/A physical interaction ComPPI
MCM2 RPL27 25348397 N/A physical interaction ComPPI
INO80B RPL27 25348397 N/A physical interaction ComPPI
RRS1 RPL27 25348397 N/A physical interaction ComPPI
RPL10A RPL27 25348397 N/A physical interaction ComPPI
RPL10 RPL27 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CD81 RPL27 25348397 N/A physical interaction ComPPI
GRB2 RPL27 12577067 24234451 25348397 association pull down ComPPI,IntAct
JUN RPL27 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
EP300 RPL27 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DHX9 RPL27 25348397 N/A physical interaction ComPPI
COPS5 RPL27 25348397 N/A physical interaction ComPPI
RPL18A RPL27 25348397 N/A physical interaction ComPPI
CUL3 RPL27 25348397 N/A physical interaction ComPPI
DLD RPL27 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RPS3A RPL27 25348397 N/A physical interaction ComPPI
HNRNPU RPL27 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PABPC4 RPL27 25348397 N/A physical interaction ComPPI
RPL28 RPL27 25348397 N/A physical interaction ComPPI
PA2G4 RPL27 15064750 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VDAC1 RPL27 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PABPC1 RPL27 25348397 N/A physical interaction ComPPI
RELA RPL27 25348397 N/A tandem affinity purification ComPPI
QARS1 RPL27 25348397 N/A physical interaction ComPPI
RPS6 RPL27 25348397 N/A physical interaction ComPPI
RPS25 RPL27 25348397 N/A physical interaction ComPPI
HUWE1 RPL27 25348397 N/A physical interaction ComPPI
RPS18 RPL27 25348397 N/A physical interaction ComPPI
RPL12 RPL27 25348397 N/A physical interaction ComPPI
RPS13 RPL27 25348397 N/A physical interaction ComPPI
RPL4 RPL27 25348397 N/A physical interaction ComPPI
RPLP0 RPL27 25348397 N/A physical interaction ComPPI
RPLP2 RPL27 25348397 N/A physical interaction ComPPI
RPLP1 RPL27 25348397 N/A physical interaction ComPPI
NEDD8 RPL27 18274552 24234451 25348397 association tandem affinity purification ComPPI,IntAct
CUL2 RPL27 25348397 N/A physical interaction ComPPI
CUL4B RPL27 25348397 N/A physical interaction ComPPI
EVPL RPL27 25348397 N/A physical interaction ComPPI
CDK2 RPL27 25348397 N/A physical interaction ComPPI
CUL1 RPL27 25348397 N/A physical interaction ComPPI
RPL7A RPL27 25348397 N/A physical interaction ComPPI
RNF2 RPL27 25348397 N/A physical interaction ComPPI
GABARAP RPL27 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CHUK RPL27 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PTEN RPL27 25348397 N/A physical interaction ComPPI
AURKA RPL27 25348397 N/A physical interaction ComPPI
MAP3K14 RPL27 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
DNM1L RPL27 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
HIF1AN RPL27 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL7 RPL27 25348397 N/A physical interaction ComPPI
MECP2 RPL27 25348397 N/A physical interaction ComPPI
H3C1 RPL27 25348397 N/A physical interaction ComPPI
CAND1 RPL27 25348397 N/A physical interaction ComPPI
SART3 RPL27 25348397 N/A physical interaction ComPPI
RPL5 RPL27 25348397 N/A physical interaction ComPPI
GAR1 RPL27 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLII RPL27 25348397 N/A physical interaction ComPPI
DDX1 RPL27 25348397 N/A physical interaction ComPPI
TRIM25 RPL27 25348397 N/A physical interaction ComPPI
MRE11 RPL27 25348397 N/A physical interaction ComPPI
BRCA1 RPL27 25348397 N/A physical interaction ComPPI
RPL6 RPL27 25348397 N/A physical interaction ComPPI
RPL23A RPL27 25348397 N/A physical interaction ComPPI
RPL13 RPL27 25348397 N/A physical interaction ComPPI
RPL23 RPL27 25348397 N/A physical interaction ComPPI
RPS9 RPL27 25348397 N/A physical interaction ComPPI
RPS10 RPL27 25348397 N/A physical interaction ComPPI
RPS20 RPL27 25348397 N/A physical interaction ComPPI
CEP250 RPL27 25348397 N/A physical interaction ComPPI
HNRNPM RPL27 25348397 N/A physical interaction ComPPI
PAN2 RPL27 25348397 N/A physical interaction ComPPI
RPL14 RPL27 25348397 N/A physical interaction ComPPI
PES1 RPL27 25348397 N/A physical interaction ComPPI
AGO2 RPL27 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RRP1B RPL27 20926688 24234451 25348397 association,physical association anti tag coimmunoprecipitation ComPPI,IntAct
IGSF8 RPL27 25348397 N/A physical interaction ComPPI
TUBGCP4 RPL27 25348397 N/A physical interaction ComPPI
DDX56 RPL27 25348397 N/A physical interaction ComPPI
RPSA RPL27 25348397 N/A physical interaction ComPPI
RPL24 RPL27 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
ICAM1 RPL27 25348397 N/A physical interaction ComPPI
ILF3 RPL27 25348397 N/A physical interaction ComPPI
RPS2 RPL27 25348397 N/A physical interaction ComPPI
CYLD RPL27 25348397 N/A physical interaction ComPPI
RPS14 RPL27 25348397 N/A physical interaction ComPPI
RPS15A RPL27 25348397 N/A physical interaction ComPPI
RPL31 RPL27 25348397 N/A physical interaction ComPPI
RPL8 RPL27 25348397 N/A physical interaction ComPPI
MTF1 RPL27 25348397 N/A physical interaction ComPPI
GABARAPL1 RPL27 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL36 RPL27 25348397 N/A physical interaction ComPPI
NOC2L RPL27 25348397 N/A physical interaction ComPPI
RPL30 RPL27 25348397 N/A physical interaction ComPPI
RPS11 RPL27 25348397 N/A physical interaction ComPPI
GTPBP4 RPL27 25348397 N/A physical interaction ComPPI
SLC25A3 RPL27 25348397 N/A physical interaction ComPPI
NEDD1 RPL27 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BRIX1 RPL27 25348397 N/A physical interaction ComPPI
RPS4X RPL27 25348397 N/A physical interaction ComPPI
RPL21 RPL27 25348397 N/A physical interaction ComPPI
RPL35A RPL27 25348397 N/A physical interaction ComPPI
RPL22 RPL27 25348397 N/A physical interaction ComPPI
DDX18 RPL27 25348397 N/A physical interaction ComPPI
RPS3 RPL27 25348397 N/A physical interaction ComPPI
RPS27 RPL27 25348397 N/A physical interaction ComPPI
RPL26 RPL27 25348397 N/A physical interaction ComPPI
PUM3 RPL27 25348397 N/A physical interaction ComPPI
RPL13A RPL27 25348397 N/A physical interaction ComPPI
RPL15 RPL27 25348397 N/A physical interaction ComPPI
RPL3 RPL27 25348397 N/A physical interaction ComPPI
RPS16 RPL27 25348397 N/A physical interaction ComPPI
CNBP RPL27 25348397 N/A physical interaction ComPPI
RPL38 RPL27 25348397 N/A physical interaction ComPPI
NDUFS1 RPL27 25348397 N/A physical interaction ComPPI
TP53 RPL27 25348397 N/A physical interaction ComPPI
BCAR1 RPL27 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
RPS19 RPL27 25348397 N/A physical interaction ComPPI
RPL32 RPL27 25348397 N/A physical interaction ComPPI
RPL34 RPL27 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
RPL35 RPL27 25348397 N/A physical interaction ComPPI
RPS29 RPL27 25348397 N/A physical interaction ComPPI
RPL37 RPL27 25348397 N/A physical interaction ComPPI
EBNA1BP2 RPL27 25348397 N/A physical interaction ComPPI
NCL RPL27 25348397 N/A physical interaction ComPPI
RPL18 RPL27 25348397 N/A physical interaction ComPPI
AGO4 RPL27 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPLP0P6 RPL27 25348397 N/A physical interaction ComPPI
RPS21 RPL27 25348397 N/A physical interaction ComPPI
NRP1 RPL27 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RPL3L RPL27 25348397 N/A physical interaction ComPPI
RPS12 RPL27 25348397 N/A physical interaction ComPPI
CRBN RPL27 25348397 N/A physical interaction ComPPI
ZC3H18 RPL27 24234451 25348397 29298432 association anti tag coimmunoprecipitation ComPPI,IntAct
RTCB RPL27 25348397 N/A physical interaction ComPPI
COX15 RPL27 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
ZBTB1 RPL27 25348397 N/A physical interaction ComPPI
MRTO4 RPL27 25348397 N/A physical interaction ComPPI
RPS5 RPL27 25348397 N/A physical interaction ComPPI
RPS8 RPL27 25348397 N/A physical interaction ComPPI
RPS23 RPL27 25348397 N/A physical interaction ComPPI
RPL27A RPL27 25348397 N/A physical interaction ComPPI
RPL27 RPS17 25348397 N/A physical interaction ComPPI
RPL27 RPS24 25348397 N/A physical interaction ComPPI
RPL27 RPL19 25348397 N/A physical interaction ComPPI
RPL27 RPL10L 25348397 N/A physical interaction ComPPI
RPL27 FUT8 25348397 N/A physical interaction ComPPI
RPL27 RPL26L1 25348397 N/A physical interaction ComPPI
RPL27 NSA2 25348397 N/A physical interaction ComPPI
RPL27 NCBP3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL27 KNOP1 25348397 N/A physical interaction ComPPI
RPL27 SOAT1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RPL27 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
METTL14 RPL27 24234451 29507755 association anti tag coimmunoprecipitation IntAct
TRPM7 RPL27 24234451 30021884 physical association cross-linking study IntAct
RPL27 ERAP2 24234451 30021884 physical association cross-linking study IntAct
RPL27 SEPTIN11 24234451 30021884 physical association cross-linking study IntAct

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