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GENE：RPL7A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RPL7A
FullNmae ribosomal protein L7a
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10364
EnsembleID ENSG00000148303
Uniprot P62424

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RPL7A pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RPL7A autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RPL7A cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
RPL7A GO:0000470,GO:0002181,GO:0002181,GO:0003723,GO:0003723,GO:0003735,GO:0003735,GO:0005515,GO:0005634,GO:0005730,GO:0005730,GO:0005737,GO:0005737,GO:0005829,GO:0005925,GO:0006412,GO:0016020,GO:0022625,GO:0022625,GO:0022625,GO:0022625,GO:0022626,GO:0042788,GO:0045202,GO:0045296

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RPL7A hsa:6130 path:hsa03010 Ribosome - Homo sapiens (human)
RPL7A hsa:6130 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
UPF1 RPL7A 19417104 23180781 physical association anti tag coimmunoprecipitation InnateDB
EED RPL7A 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 RPL7A 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 RPL7A 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink

Source Target Pmid Interactiontype Methods Database
URS000032FC1A RPL7A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000041FA2C RPL7A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE RPL7A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 RPL7A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC RPL7A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD RPL7A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000F4AC3 RPL7A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A405B RPL7A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 RPL7A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000C85B2 RPL7A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E RPL7A 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
LGALS3 RPL7A 25348397 N/A physical interaction ComPPI
SNW1 RPL7A 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SOCS3 RPL7A 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RPL9 RPL7A 25348397 N/A physical interaction ComPPI
RPS7 RPL7A 25348397 N/A physical interaction ComPPI
NPM1 RPL7A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPS28 RPL7A 25348397 N/A physical interaction ComPPI
RPL37A RPL7A 25348397 N/A physical interaction ComPPI
UBL4A RPL7A 25348397 N/A physical interaction ComPPI
GABARAPL2 RPL7A 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL11 RPL7A 25348397 N/A physical interaction ComPPI
ACTB RPL7A 15047060 24234451 25348397 physical association molecular sieving ComPPI,IntAct
RPS15 RPL7A 25348397 N/A physical interaction ComPPI
RPS26 RPL7A 25348397 N/A physical interaction ComPPI
KEAP1 RPL7A 25348397 N/A physical interaction ComPPI
MCM2 RPL7A 25348397 N/A physical interaction ComPPI
SLC25A6 RPL7A 25348397 N/A physical interaction ComPPI
HSP90AB1 RPL7A 25348397 N/A physical interaction ComPPI
INO80B RPL7A 25348397 N/A physical interaction ComPPI
RACK1 RPL7A 25348397 N/A physical interaction ComPPI
RRS1 RPL7A 25348397 N/A physical interaction ComPPI
RPL10A RPL7A 25348397 N/A physical interaction ComPPI
PAK1 RPL7A 25348397 N/A two hybrid,physical interaction ComPPI
RPL10 RPL7A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JUN RPL7A 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
RPL18A RPL7A 25348397 N/A physical interaction ComPPI
CTBP2 RPL7A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CUL3 RPL7A 25348397 N/A physical interaction ComPPI
RPS27A RPL7A 25348397 N/A physical interaction ComPPI
NTRK1 RPL7A 25348397 N/A physical interaction ComPPI
CDH1 RPL7A 25348397 N/A physical interaction ComPPI
RPS3A RPL7A 25348397 N/A physical interaction ComPPI
HNRNPU RPL7A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL28 RPL7A 25348397 N/A physical interaction ComPPI
EEF1A1 RPL7A 25348397 N/A physical interaction ComPPI
CD247 RPL7A 24234451 24502978 25348397 association pull down ComPPI,IntAct
MKNK2 RPL7A 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EIF2S1 RPL7A 25348397 N/A physical interaction ComPPI
PABPC1 RPL7A 25348397 N/A physical interaction ComPPI
EWSR1 RPL7A 25348397 N/A physical interaction ComPPI
XPO1 RPL7A 25348397 N/A physical interaction ComPPI
QARS1 RPL7A 25348397 N/A physical interaction ComPPI
TRAP1 RPL7A 25348397 N/A physical interaction ComPPI
ARRB1 RPL7A 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPS6 RPL7A 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
RPS25 RPL7A 25348397 N/A physical interaction ComPPI
HUWE1 RPL7A 25348397 N/A physical interaction ComPPI
RPS18 RPL7A 25348397 N/A physical interaction ComPPI
RPL12 RPL7A 25348397 N/A physical interaction ComPPI
RPS13 RPL7A 25348397 N/A physical interaction ComPPI
RPL4 RPL7A 25348397 N/A physical interaction ComPPI
RPLP0 RPL7A 25348397 N/A physical interaction ComPPI
RPLP2 RPL7A 25348397 N/A physical interaction ComPPI
RPLP1 RPL7A 25348397 N/A physical interaction ComPPI
NEDD8 RPL7A 18274552 24234451 25348397 association tandem affinity purification ComPPI,IntAct
ARRB2 RPL7A 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL4A RPL7A 25348397 N/A physical interaction ComPPI
RPL7A CCDC47 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RPL7A MYZAP 25348397 N/A physical interaction,two hybrid fragment pooling approach ComPPI
RPL7A POLR2M 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
RPL7A SRRM2 25348397 N/A physical interaction ComPPI
RPL7A ESR1 21182205 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient,physical interaction ComPPI,IntAct
RPL7A HDAC5 25348397 N/A physical interaction ComPPI
RPL7A DYRK2 25348397 N/A physical interaction ComPPI
RPL7A STAU1 14525934 15303970 24234451 25348397 association,physical association affinity chromatography technology,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
RPL7A VHL 25348397 N/A physical interaction ComPPI
RPL7A SIRT7 25348397 N/A physical interaction ComPPI
RPL7A ERG 25348397 N/A physical interaction ComPPI
RPL7A NFX1 25348397 N/A physical interaction ComPPI
RPL7A RPL21 25348397 N/A physical interaction ComPPI
RPL7A RPL6 25348397 N/A physical interaction ComPPI
RPL7A RPL7 25348397 N/A physical interaction ComPPI
RPL7A RPS3 25348397 N/A physical interaction ComPPI
RPL7A RPS9 25348397 N/A physical interaction ComPPI
RPL7A RPLP0P6 25348397 N/A physical interaction ComPPI
RPL7A RPL13 25348397 N/A physical interaction ComPPI
RPL7A RPL15 25348397 N/A physical interaction ComPPI
RPL7A RPL17 25348397 N/A physical interaction ComPPI
RPL7A RPL18 25348397 N/A physical interaction ComPPI
RPL7A RPL19 25348397 N/A physical interaction ComPPI
RPL7A RPL27A 25348397 N/A physical interaction ComPPI
RPL7A RPL30 25348397 N/A physical interaction ComPPI
RPL7A RPL31 25348397 N/A physical interaction ComPPI
RPL7A RPL5 25348397 N/A physical interaction ComPPI
RPL7A RPL8 25348397 N/A physical interaction ComPPI
RPL7A RPS15A 25348397 N/A physical interaction ComPPI
RPL7A RPS16 25348397 N/A physical interaction ComPPI
RPL7A RPS19 25348397 N/A physical interaction ComPPI
RPL7A RPS20 25348397 N/A physical interaction ComPPI
RPL7A RPS23 25348397 N/A physical interaction ComPPI
RPL7A RPS2 25348397 N/A physical interaction ComPPI
RPL7A RPS4X 25348397 N/A physical interaction ComPPI
RPL7A RPS5 25348397 N/A physical interaction ComPPI
RPL7A RPS8 25348397 N/A physical interaction ComPPI
RPL7A RPSA 25348397 N/A physical interaction ComPPI
RPL7A RPL3 25348397 N/A physical interaction ComPPI
RPL7A RPS24 25348397 N/A physical interaction ComPPI
RPL7A RPS12 25348397 N/A physical interaction ComPPI
RPL7A RPL23A 25348397 N/A physical interaction ComPPI
RPL7A RPL24 25348397 N/A physical interaction ComPPI
RPL7A RPS11 25348397 N/A physical interaction ComPPI
RPL7A RPL22 25348397 N/A physical interaction ComPPI
RPL7A RPL36 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
RPL7A RPL35 25348397 N/A physical interaction ComPPI
RPL7A RPL38 25348397 N/A physical interaction ComPPI
RPL7A RPS21 25348397 N/A physical interaction ComPPI
RPL7A RPL32 25348397 N/A physical interaction ComPPI
RPL7A EEF2 25348397 N/A physical interaction ComPPI
RPL7A EEF1A1P5 25348397 N/A physical interaction ComPPI
RPL7A RPL29 25348397 N/A physical interaction ComPPI
RPL7A NCL 25348397 N/A physical interaction ComPPI
RPL7A ILF3 25348397 N/A physical interaction ComPPI
RPL7A SLC25A5 25348397 N/A physical interaction ComPPI
RPL7A HNRNPM 25348397 N/A physical interaction ComPPI
RPL7A ACTA2 25348397 N/A physical interaction ComPPI
RPL7A LUC7L2 25348397 N/A physical interaction ComPPI
RPL7A RPS27L 25348397 N/A physical interaction ComPPI
RPL7A RPL10L 25348397 N/A physical interaction ComPPI
RPL7A MRPL12 25348397 N/A physical interaction ComPPI
RPL7A SLC25A10 25348397 N/A physical interaction ComPPI
RPL7A UPF1 19417104 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL7A MAGOH 23084401 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL7A FN1 25348397 N/A physical interaction ComPPI
RPL7A VCAM1 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
RPL7A ITGA4 25348397 N/A physical interaction ComPPI
RPL7A PAN2 25348397 N/A physical interaction ComPPI
RPL7A IGSF8 25348397 N/A physical interaction ComPPI
RPL7A ICAM1 25348397 N/A physical interaction ComPPI
RPL7A FBXO6 25348397 N/A physical interaction ComPPI
RPL7A TARDBP 25348397 N/A physical interaction ComPPI
RPL7A PRKN 25348397 N/A physical interaction ComPPI
RPL7A AIMP1 25348397 N/A physical interaction ComPPI
RPL7A DARS1 25348397 N/A physical interaction ComPPI
RPL7A EEF1E1 25348397 N/A physical interaction ComPPI
RPL7A RPL26 25348397 N/A physical interaction ComPPI
RPL7A CEP250 25348397 N/A physical interaction ComPPI
RPL7A TP53 25348397 N/A physical interaction ComPPI
RPL7A CUL7 25348397 N/A physical interaction ComPPI
RPL7A OBSL1 25348397 N/A physical interaction ComPPI
RPL7A CCDC8 25348397 N/A physical interaction ComPPI
RPL7A EED 25348397 N/A physical interaction ComPPI
RPL7A RNF2 25348397 N/A physical interaction ComPPI
RPL7A DDX18 25348397 N/A physical interaction ComPPI
RPL7A PES1 25348397 N/A physical interaction ComPPI
RPL7A RPL26L1 25348397 N/A physical interaction ComPPI
RPL7A RPL35A 25348397 N/A physical interaction ComPPI
RPL7A RPL3L 25348397 N/A physical interaction ComPPI
RPL7A BRIX1 25348397 N/A physical interaction ComPPI
RPL7A RPL13A 25348397 N/A physical interaction ComPPI
RPL7A RPL27 25348397 N/A physical interaction ComPPI
RPL7A RPL34 25348397 N/A physical interaction ComPPI
RPL7A RPS10 25348397 N/A physical interaction ComPPI
RPL7A RPS27 25348397 N/A physical interaction ComPPI
RPL7A SFN 25348397 N/A physical interaction ComPPI
RPL7A TTK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL7A NOP56 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL7A ZNF746 25348397 N/A physical interaction ComPPI
RPL7A PUM3 25348397 N/A physical interaction ComPPI
RPL7A MECP2 25348397 N/A physical interaction ComPPI
RPL7A KNOP1 25348397 N/A physical interaction ComPPI
RPL7A SART3 25348397 N/A physical interaction ComPPI
RPL7A ZC3HAV1 25348397 N/A physical interaction ComPPI
RPL7A MAK16 25348397 N/A physical interaction ComPPI
RPL7A RBM34 25348397 N/A physical interaction ComPPI
RPL7A BHLHA15 25348397 N/A physical interaction ComPPI
RPL7A DGCR8 25348397 N/A physical interaction ComPPI
RPL7A RRP8 25348397 N/A physical interaction ComPPI
RPL7A ZNF2 25348397 N/A physical interaction ComPPI
RPL7A CNBP 25348397 N/A physical interaction ComPPI
RPL7A MACROH2A2 25348397 N/A physical interaction ComPPI
RPL7A NOP53 25348397 N/A physical interaction ComPPI
RPL7A CYLD 25348397 N/A physical interaction ComPPI
RPL7A TRIM25 25348397 N/A physical interaction ComPPI
RPL7A BRCA1 25348397 N/A physical interaction ComPPI
RPL7A YAP1 25348397 N/A physical interaction ComPPI
RPL7A MTF1 25348397 N/A physical interaction ComPPI
RPL7A NFKB2 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RPL7A AGO1 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL7A AGO2 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL7A PPP2R2B 19156129 24234451 25348397 association pull down ComPPI,IntAct
RPL7A ESR2 21182203 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient ComPPI,IntAct
RPL7A GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL7A GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL7A NXF1 18596238 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL7A NOM1 21576267 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL7A DUX4 24234451 25348397 26816005 association pull down ComPPI,IntAct
RPL7A RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL7A ZC3H18 24234451 25348397 29298432 association anti tag coimmunoprecipitation ComPPI,IntAct
MAP3K14 RPL7A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
H3C1 RPL7A 25348397 N/A physical interaction ComPPI
ILF2 RPL7A 25348397 N/A physical interaction ComPPI
RPL23 RPL7A 25348397 N/A physical interaction ComPPI
PSMB1 RPL7A 25348397 N/A physical interaction ComPPI
RPL14 RPL7A 25348397 N/A physical interaction ComPPI
EEF1B2 RPL7A 25348397 N/A physical interaction ComPPI
EIF4A3 RPL7A 23084401 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPS14 RPL7A 25348397 N/A physical interaction ComPPI
EBNA1BP2 RPL7A 25348397 N/A physical interaction ComPPI
FOXO RPL7A 25348397 N/A physical interaction ComPPI
RPL7A AGO 15710747 24234451 25348397 physical association physical interaction,two hybrid fragment pooling approach ComPPI,IntAct
RPL7A TAK1 25348397 N/A physical interaction ComPPI
RPL7A MYC 25348397 N/A physical interaction ComPPI
RPL7A CHICO 25348397 N/A physical interaction ComPPI
RPL7A POLR2M 14525934 16169070 N/A two hybrid HPRD
SGO1 RPL7A 14525934 16541025 N/A experimental interaction detection HPRD
METTL14 RPL7A 24234451 29507755 association anti tag coimmunoprecipitation IntAct
RPL7A SLC23A2 24234451 30021884 physical association cross-linking study IntAct
RPL7A TMEM35A 24234451 30021884 physical association cross-linking study IntAct
RPL7A CACYBP 24234451 30021884 physical association cross-linking study IntAct
RPL7A ZHX3 24234451 30021884 physical association cross-linking study IntAct
RPL7A NOLC1 24234451 30021884 physical association cross-linking study IntAct
RPL7A ULK4 24234451 30021884 physical association cross-linking study IntAct
RPL7A ASNS 24234451 30021884 physical association cross-linking study IntAct
RSL1D1 RPL7A 24234451 30021884 physical association cross-linking study IntAct
RPL7A MYH14 24234451 30021884 physical association cross-linking study IntAct
RPL7A CFAP77 24234451 30021884 physical association cross-linking study IntAct
RPL7A RPL7L1 24234451 30021884 physical association cross-linking study IntAct
H2BC9 RPL7A 24234451 30021884 physical association cross-linking study IntAct
RPL7A FHIP1B 24234451 30021884 physical association cross-linking study IntAct
RPL7A ANXA6 24234451 30021884 physical association cross-linking study IntAct
RPL7A SYNE2 24234451 30021884 physical association cross-linking study IntAct
L1TD1 RPL7A 24234451 25702638 association anti bait coimmunoprecipitation IntAct
TPT1 RPL7A 24234451 27607350 association anti bait coimmunoprecipitation IntAct

Visualization










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