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GENE：RPS19

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RPS19
FullNmae ribosomal protein S19
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10402
EnsembleID ENSG00000105372
Uniprot P39019

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RPS19 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
RPS19 GO:0000028,GO:0000028,GO:0000462,GO:0002181,GO:0002181,GO:0002548,GO:0003723,GO:0003723,GO:0003735,GO:0003735,GO:0003735,GO:0003735,GO:0005515,GO:0005654,GO:0005654,GO:0005730,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0005840,GO:0005925,GO:0006364,GO:0006412,GO:0007000,GO:0009991,GO:0014069,GO:0014069,GO:0016020,GO:0017134,GO:0019901,GO:0022626,GO:0022627,GO:0022627,GO:0022627,GO:0022627,GO:0030218,GO:0030490,GO:0031640,GO:0032040,GO:0042274,GO:0042274,GO:0042802,GO:0050829,GO:0060265,GO:0060266,GO:0061844,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RPS19 hsa:6223 path:hsa03010 Ribosome - Homo sapiens (human)
RPS19 hsa:6223 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 RPS19 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
APP RPS19 21832049 23180781 physical association protein array InnateDB
MECOM RPS19 23180781 23858473 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 RPS19 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 RPS19 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 RPS19 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC RPS19 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 RPS19 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RPS19 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 RPS19 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RPS19 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RPS19 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR RPS19 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 RPS19 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 RPS19 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EEE35 RPS19 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001E0AEA RPS19 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000036AFF1 RPS19 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002198F3 RPS19 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000027352D RPS19 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 RPS19 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C RPS19 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 RPS19 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 RPS19 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 RPS19 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 RPS19 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB0E RPS19 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000122F23 RPS19 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 RPS19 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC RPS19 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA RPS19 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000013DD8 RPS19 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F RPS19 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CAMK1 RPS19 22135298 phosphorylation N/A PhosphoSite
PRKACA RPS19 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
SNW1 RPS19 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CUL5 RPS19 25348397 N/A physical interaction ComPPI
EIF1B RPS19 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RPL9 RPS19 25348397 N/A physical interaction ComPPI
RPS7 RPS19 25348397 N/A physical interaction ComPPI
NPM1 RPS19 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPS28 RPS19 25348397 N/A physical interaction ComPPI
PPP2R1A RPS19 25348397 N/A physical interaction ComPPI
RPL37A RPS19 25348397 N/A physical interaction ComPPI
UBL4A RPS19 25348397 N/A physical interaction ComPPI
KPNA1 RPS19 25348397 N/A physical interaction ComPPI
GABARAPL2 RPS19 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL11 RPS19 25348397 N/A physical interaction ComPPI
ACTB RPS19 15047060 24234451 25348397 physical association molecular sieving ComPPI,IntAct
RPS15 RPS19 25348397 N/A physical interaction ComPPI
RPS26 RPS19 25348397 N/A physical interaction ComPPI
RAD21 RPS19 25348397 N/A physical interaction ComPPI
KEAP1 RPS19 25348397 N/A physical interaction ComPPI
MCM2 RPS19 25348397 N/A physical interaction ComPPI
EIF3E RPS19 25348397 N/A physical interaction ComPPI
CRK RPS19 25348397 N/A physical interaction ComPPI
CPSF7 RPS19 25348397 N/A physical interaction ComPPI
RRS1 RPS19 25348397 N/A physical interaction ComPPI
RPL10A RPS19 25348397 N/A physical interaction ComPPI
CD4 RPS19 25348397 N/A physical interaction ComPPI
CBL RPS19 25348397 N/A physical interaction ComPPI
RPL10 RPS19 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CD81 RPS19 25348397 N/A physical interaction ComPPI
PIM1 RPS19 16266891 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,two hybrid,pull down,in-gel kinase assay ComPPI,IntAct
SHC1 RPS19 25348397 N/A physical interaction ComPPI
GRB2 RPS19 25348397 N/A physical interaction ComPPI
JUN RPS19 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 RPS19 25348397 N/A physical interaction ComPPI
RPL18A RPS19 25348397 N/A physical interaction ComPPI
INPPL1 RPS19 25348397 N/A physical interaction ComPPI
CUL3 RPS19 25348397 N/A physical interaction ComPPI
RPS27A RPS19 25348397 N/A physical interaction ComPPI
UBA52 RPS19 25348397 N/A physical interaction ComPPI
RPS3A RPS19 25348397 N/A physical interaction ComPPI
RRBP1 RPS19 25348397 N/A physical interaction ComPPI
HEY1 RPS19 25348397 N/A physical interaction ComPPI
HNRNPU RPS19 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL28 RPS19 25348397 N/A physical interaction ComPPI
EEF1A1 RPS19 25348397 N/A physical interaction ComPPI
TRIM29 RPS19 25348397 N/A physical interaction ComPPI
EWSR1 RPS19 25348397 N/A physical interaction ComPPI
TRAP1 RPS19 25348397 N/A physical interaction ComPPI
RPS6 RPS19 25348397 N/A physical interaction ComPPI
RPS25 RPS19 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
HUWE1 RPS19 25348397 N/A physical interaction ComPPI
RPS18 RPS19 25348397 N/A physical interaction ComPPI
RPL12 RPS19 25348397 N/A physical interaction ComPPI
RPS13 RPS19 20951136 24234451 25348397 colocalization cosedimentation through density gradient,physical interaction ComPPI,IntAct
RPL4 RPS19 25348397 N/A physical interaction ComPPI
RPLP0 RPS19 25348397 N/A physical interaction ComPPI
RPLP2 RPS19 25348397 N/A physical interaction ComPPI
RPLP1 RPS19 25348397 N/A physical interaction ComPPI
HNRNPA2B1 RPS19 25348397 N/A physical interaction ComPPI
ARRB2 RPS19 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATP1B1 RPS19 25348397 N/A physical interaction ComPPI
CDK2 RPS19 25348397 N/A physical interaction ComPPI
CUL1 RPS19 25348397 N/A physical interaction ComPPI
H1-4 RPS19 25348397 N/A physical interaction ComPPI
RPL7A RPS19 25348397 N/A physical interaction ComPPI
SFN RPS19 25348397 N/A physical interaction ComPPI
VHL RPS19 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SPG21 RPS19 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PINX1 RPS19 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF2 RPS19 25348397 N/A physical interaction ComPPI
AURKA RPS19 25348397 N/A physical interaction ComPPI
VCAM1 RPS19 19738201 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
ITGA4 RPS19 25348397 N/A physical interaction ComPPI
RPL7 RPS19 25348397 N/A physical interaction ComPPI
STX7 RPS19 25348397 N/A physical interaction ComPPI
PRKN RPS19 25348397 N/A physical interaction ComPPI
CAND1 RPS19 25348397 N/A physical interaction ComPPI
RBMS1 RPS19 25348397 N/A physical interaction ComPPI
RFX5 RPS19 25348397 N/A physical interaction ComPPI
NFKB2 RPS19 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RPL5 RPS19 25348397 N/A physical interaction ComPPI
SMURF1 RPS19 25348397 N/A physical interaction ComPPI
TRIM25 RPS19 25348397 N/A physical interaction ComPPI
EIF2S2 RPS19 25348397 N/A physical interaction ComPPI
PRPF4 RPS19 25348397 N/A physical interaction ComPPI
POT1 RPS19 25348397 N/A physical interaction ComPPI
RPS6KB2 RPS19 25348397 N/A physical interaction ComPPI
BRCA1 RPS19 25348397 N/A physical interaction ComPPI
RPL6 RPS19 25348397 N/A physical interaction ComPPI
RPL23A RPS19 25348397 N/A physical interaction ComPPI
RPL13 RPS19 25348397 N/A physical interaction ComPPI
RPL23 RPS19 25348397 N/A physical interaction ComPPI
EEF2 RPS19 25348397 N/A physical interaction ComPPI
SRRM2 RPS19 25348397 N/A physical interaction ComPPI
RPS9 RPS19 25348397 N/A physical interaction ComPPI
RPS10 RPS19 25348397 N/A physical interaction ComPPI
RPS20 RPS19 25348397 N/A physical interaction ComPPI
IKBKE RPS19 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CEP250 RPS19 25348397 N/A physical interaction ComPPI
ASCC2 RPS19 25348397 N/A physical interaction ComPPI
PAN2 RPS19 25348397 N/A physical interaction ComPPI
FGF2 RPS19 11716516 14525934 24234451 25348397 27898060 physical association coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct,OmniPath
RPL14 RPS19 25348397 N/A physical interaction ComPPI
PIN4 RPS19 25348397 N/A physical interaction ComPPI
THRAP3 RPS19 25348397 N/A physical interaction ComPPI
SRRM1 RPS19 25348397 N/A physical interaction ComPPI
TUBGCP2 RPS19 25348397 N/A physical interaction ComPPI
IGSF8 RPS19 25348397 N/A physical interaction ComPPI
TUBGCP4 RPS19 25348397 N/A physical interaction ComPPI
RPSA RPS19 25348397 N/A physical interaction ComPPI
RPL24 RPS19 25348397 N/A physical interaction ComPPI
ICAM1 RPS19 25348397 N/A physical interaction ComPPI
RPS2 RPS19 25348397 N/A physical interaction ComPPI
NME2 RPS19 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SLC25A5 RPS19 25348397 N/A physical interaction ComPPI
CYLD RPS19 25348397 N/A physical interaction ComPPI
RPS14 RPS19 20951136 24234451 25348397 colocalization cosedimentation through density gradient,physical interaction ComPPI,IntAct
RPS15A RPS19 25348397 N/A physical interaction ComPPI
RPL31 RPS19 25348397 N/A physical interaction ComPPI
RPL8 RPS19 25348397 N/A physical interaction ComPPI
TXNDC11 RPS19 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MTF1 RPS19 25348397 N/A physical interaction ComPPI
GABARAPL1 RPS19 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL36 RPS19 25348397 N/A physical interaction ComPPI
RPL30 RPS19 25348397 N/A physical interaction ComPPI
POU5F1 RPS19 25348397 N/A physical interaction ComPPI
RPS11 RPS19 20951136 24234451 25348397 colocalization cosedimentation through density gradient,physical interaction ComPPI,IntAct
NQO1 RPS19 25348397 N/A physical interaction ComPPI
NEDD1 RPS19 25348397 N/A physical interaction ComPPI
FAU RPS19 25348397 N/A physical interaction ComPPI
RPS4X RPS19 25348397 N/A physical interaction ComPPI
RPL21 RPS19 25348397 N/A physical interaction ComPPI
RPL35A RPS19 25348397 N/A physical interaction ComPPI
RPL22 RPS19 25348397 N/A physical interaction ComPPI
SIRT7 RPS19 25348397 N/A physical interaction ComPPI
RPL17 RPS19 25348397 N/A physical interaction ComPPI
RPS3 RPS19 25348397 N/A physical interaction ComPPI
RPS27 RPS19 25348397 N/A physical interaction ComPPI
RPL26 RPS19 25348397 N/A physical interaction ComPPI
RPL13A RPS19 25348397 N/A physical interaction ComPPI
RPL15 RPS19 25348397 N/A physical interaction ComPPI
RPL3 RPS19 25348397 N/A physical interaction ComPPI
RPS16 RPS19 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
CNBP RPS19 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GH1 RPS19 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RPL38 RPS19 25348397 N/A physical interaction ComPPI
FN1 RPS19 25348397 N/A physical interaction ComPPI
APP RPS19 25348397 N/A physical interaction ComPPI
EEF1A1P5 RPS19 25348397 N/A physical interaction ComPPI
TP53 RPS19 25348397 N/A physical interaction ComPPI
SERBP1 RPS19 25348397 N/A physical interaction ComPPI
MAGEB2 RPS19 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TSR1 RPS19 25348397 N/A physical interaction ComPPI
RPS19 NFX1 25348397 N/A physical interaction ComPPI
RPS19 RPL18 25348397 N/A physical interaction ComPPI
RPS19 RPL19 25348397 N/A physical interaction ComPPI
RPS19 RPS23 25348397 N/A physical interaction ComPPI
RPS19 RPS5 25348397 N/A physical interaction ComPPI
RPS19 RPS8 20951136 24234451 25348397 colocalization cosedimentation through density gradient,physical interaction ComPPI,IntAct
RPS19 RPS12 25348397 N/A physical interaction ComPPI
RPS19 RPS24 25348397 N/A physical interaction ComPPI
RPS19 RPL35 25348397 N/A physical interaction ComPPI
RPS19 RPS21 25348397 N/A physical interaction ComPPI
RPS19 RPL10L 25348397 N/A physical interaction ComPPI
RPS19 STT3B 25348397 N/A physical interaction ComPPI
RPS19 MRRF 25348397 N/A physical interaction ComPPI
RPS19 ACAA1 25348397 N/A physical interaction ComPPI
RPS19 TBL2 25348397 N/A physical interaction ComPPI
RPS19 SUGP1 25348397 N/A physical interaction ComPPI
RPS19 MRPS28 25348397 N/A physical interaction ComPPI
RPS19 RAD52 19338310 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPS19 RPS17 25348397 N/A physical interaction ComPPI
RPS19 EIF2A 25348397 N/A physical interaction ComPPI
RPS19 FAU 25348397 N/A physical interaction ComPPI
RPS19 RPS29 25348397 N/A physical interaction ComPPI
RPS19 PYM1 25348397 N/A physical interaction ComPPI
RPS19 CCDC8 25348397 N/A physical interaction ComPPI
RPS19 RPL27 25348397 N/A physical interaction ComPPI
RPS19 RPL27A 25348397 N/A physical interaction ComPPI
RPS19 ATP1B3 25348397 N/A physical interaction ComPPI
RPS19 KLHDC4 25348397 N/A physical interaction ComPPI
RPS19 RPLP0P6 25348397 N/A physical interaction ComPPI
RPS19 RC3H1 25348397 N/A physical interaction ComPPI
RPS19 PRPF31 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
RPS19 MEX3C 22863774 24234451 25348397 association pull down ComPPI,IntAct
RPS19 LRRK2 24234451 24725412 25348397 association tandem affinity purification ComPPI,IntAct
RPS19 ZC3H18 24234451 25348397 29298432 association anti tag coimmunoprecipitation ComPPI,IntAct
NCL RPS19 25348397 N/A physical interaction ComPPI
MRPL53 RPS19 25348397 N/A physical interaction ComPPI
RPS19 C5AR1 11733378 14525934 N/A experimental interaction detection HPRD
RPS19 RPS19 11226885 14525934 24234451 physical association coimmunoprecipitation,experimental interaction detection HPRD,IntAct
RPS19BP1 RPS19 14525934 16289379 27898060 N/A experimental interaction detection,two hybrid HPRD,OmniPath
RPS19 VDAC2 24234451 30021884 physical association cross-linking study IntAct
H1-5 RPS19 24234451 30021884 physical association cross-linking study IntAct
PRKACA RPS19 19200342 27898060 N/A N/A OmniPath
PIM1 RPS19 16266891 27898060 stimulant N/A OmniPath
RPS19 C5AR1 11107061 11733378 27898060 N/A N/A OmniPath

Visualization










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